Gene Information

Name : pepA (EcSMS35_4740)
Accession : YP_001746663.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 4839389 - 4840900 bp
Length : 1512 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTTAGTGTAAAAAGCGGTAGCCCGGAGAAACAGCGGAGTGCCTGCATCGTCGTGGGCGTCTTCGAACCACGTCG
CCTTTCTCCGATTGCAGAACAGCTCGATAAAATCAGCGATGGGTACATCAGCGCCCTGCTACGTCGGGGCGAACTGGAAG
GAAAACCGGGGCAGACACTGTTGCTGCACCATGTTCCGAATGTACTTTCCGAGCGAATTCTCCTTATTGGTTGCGGCAAA
GAACGTGAGCTGGATGAACGTCAGTACAAGCAGGTTATTCAGAAAACCATTAATACGCTGAATGATACTGGCTCAATGGA
AGCGGTCTGCTTTCTGACTGAACTGCACGTTAAAGGCCGTAACAACTACTGGAAAGTGCGTCAGGCTGTCGAGACTGCAA
AAGAGACGCTCTACAGTTTCGATCAGCTGAAAACGAACAAGAGCGAACCGCGTCGTCCGCTGCGTAAAATGGTGTTCAAC
GTGCCGACCCGCCGTGAACTGACCAGCGGTGAGCGCGCGATCCAGCACGGTCTGGCGATTGCCGCCGGGATTAAAGCAGC
AAAAGATCTCGGCAATATGCCGCCGAATATCTGTAACGCCGCTTACCTCGCTTCACAAGCGCGCCAGCTGGCTGACAGCT
ACAGCAAGAATGTCATCACCCGCGTTATCGGCGAACAGCAGATGAAAGAGCTGGGGATGCATTCTTATCTGGCGGTCGGT
CAGGGTTCGCAGAACGAATCGCTGATGTCGGTGATTGAGTACAAAGGCAACGCGTCGGAAGATGCTCGCCCAATCGTGCT
GGTGGGTAAAGGTTTAACCTTCGACTCCGGCGGTATCTCCATCAAGCCTTCAGAAGGCATGGATGAGATGAAGTACGATA
TGTGCGGCGCGGCGGCGGTTTACGGCGTGATGCGTATGGTCGCGGAGCTGCAACTGCCGATTAACGTTATCGGCGTGCTG
GCAGGCTGCGAAAACATGCCTGGCGGGCGTGCCTATCGTCCGGGCGATGTGTTAACCACCATGTCCGGTCAAACCGTTGA
AGTGCTGAACACCGATGCCGAAGGCCGCCTGGTACTGTGCGACGTGTTAACTTACGTTGAACGTTTTGAGCCGGAAGCGG
TGATTGATGTGGCGACGCTGACCGGTGCCTGCGTGATCGCGCTGGGTCATCATATTACTGGTCTGATGGCGAACCATAAT
CCGCTGGCCCATGAACTGATTGCCGCGTCTGAACAATCCGGTGACCGCGCATGGCGCTTACCGCTGGGTGACGAGTATCA
GGAACAACTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGTCGTCCTGGTGGGGCGATTACCGCAGGTTGCTTCC
TGTCACGCTTTACCCGTAAGTACAACTGGGCGCACCTGGATATTGCAGGAACCGCCTGGCGTTCTGGTAAAGCAAAAGGC
GCAACCGGTCGTCCGGTAGCGTTGCTGGCACAGTTCCTGCTGAATCGCGCTGGGTTTAACGGCGAAGAGTAA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-90 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-90 55