Gene Information

Name : actP (EcSMS35_4529)
Accession : YP_001746457.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 4629297 - 4630946 bp
Length : 1650 bp
Strand : -
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGAAAAGAGTTCTGACGGCGCTTGCCGCCACACTCCCTTTCGCAGCTAACGCCGCGGATGCTATTAGCGGGGCCGTAGA
GCGCCAGCCAACAAACTGGCAGGCGATTATTATGTTCCTGATTTTCGTCGTGTTTACGCTCGGCATTACCTACTGGGCGT
CAAAACGCGTACGTTCGCGTAATGACTACTACACCGCAGGCGGCAATATCACCGGTTTTCAGAACGGGCTGGCGATTGCC
GGGGACTATATGTCCGCCGCCTCATTCTTGGGGATCTCCGCGCTGGTGTTTACCTCCGGCTATGACGGGCTGATCTACTC
GTTGGGCTTCCTGGTGGGCTGGCCAATCATTCTGTTCCTGATTGCCGAACGTCTGCGTAACCTCGGTCGCTACACCTTTG
CCGATGTGGCCTCTTACCGTCTGAAACAAGGGCCGATTCGTATTCTTTCGGCCTGTGGTTCTCTGGTGGTGGTGGCGCTT
TACCTTATCGCCCAGATGGTAGGTGCAGGTAAACTCATCGAGCTGCTGTTTGGCCTTAACTATCACATTGCGGTGGTGCT
GGTCGGCGTGCTGATGATGATGTACGTCCTGTTCGGCGGCATGCTGGCGACCACCTGGGTACAGATTATCAAAGCCGTTC
TGTTGCTGTTCGGTGCCAGCTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAACAATCTGTTCAGCGAA
GCGATGGCGGTACACCCGAAAGGTGTCGACATCATGAAGCCGGGCGGGCTGGTGAAAGATCCTATCTCCGCGCTCTCTTT
GGGGCTAGGACTGATGTTTGGTACGGCTGGCTTGCCGCATATTCTGATGCGCTTCTTTACGGTCAGCGATGCCCGCGAAG
CACGTAAGAGCGTGTTCTACGCCACCGGATTTATGGGCTACTTCTACATCCTGACCTTTATTATCGGCTTCGGCGCAATC
ATGCTGGTTGGTGCGAATCCGGAATATAAAGACGCGGCGGGCCATCTGATTGGTGGTAACAACATGGCAGCAGTTCACCT
GGCGAATGCAGTGGGTGGCAACCTGTTCCTCGGCTTTATTTCAGCGGTTGCTTTCGCCACCATTCTTGCGGTGGTTGCGG
GTCTGACGCTGGCGGGCGCATCGGCGGTGTCTCACGACCTGTACGCTAACGTCTTCAAAAAAGGTGCGACCGAACGTGAA
GAGCTGCGGGTATCGAAAATCACCGTACTGATCCTCGGTGTGATTGCCATTATCCTCGGCGTGCTGTTTGAGAATCAGAA
CATCGCCTTTATGGTGGGGCTGGCGTTTGCCATCGCGGCGAGCTGTAACTTCCCGATCATTCTGCTTTCCATGTACTGGT
CGAAACTGACTACCCGTGGCGCGATGCTGGGCGGCTGGTTAGGACTGATTACTGCGGTGGTGCTGATGATCCTCGGCCCG
ACGATTTGGGTACAGATCCTCGGTCACGAAAAAGCCATCTTCCCGTATGAATACCCGGCGCTGTTCTCTATCAGCGTGGC
ATTCCTCGGCATCTGGTTCTTCTCGGCAACCGATAACTCAGCGGAAGGCGCGCGTGAGCGTGAACTGTTCCGTGCGCAGT
TTATCCGTTCCCAGACCGGCTTTGGCGTTGAGCAAGGCCGCGCGCATTAA

Protein sequence :
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 1e-122 58
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 1e-66 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP YP_001746457.1 acetate permease BAC0564 Protein 0.0 99
actP YP_001746457.1 acetate permease BAC0570 Protein 9e-135 65