Gene Information

Name : EcSMS35_4018 (EcSMS35_4018)
Accession : YP_001745981.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Virulence
Product : putative type III secretion chaperone SicA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4097155 - 4097652 bp
Length : 498 bp
Strand : +
Note : identified by match to protein family HMM PF07720; match to protein family HMM TIGR02552

DNA sequence :
ATGGAAAGCGCAAATCTGGATTTAGAAGAAAATAAAGAAATTGCCAGTAAGTTCGAACGTGCATTAGGTATGGGAGCAAC
GCTTGCAGAGCTGCATGGCATAACCCCGGATACCCTTGAAGGCGTTTATGCTTACGCTTATAACTTTTATGAAAAAGGAA
GACTTGACGAAGCTGAACTTTTTTTTAAATTTCTCTGTATTTATGATTTCCAAAATTATAACTACTTAAAAGGATATGCC
GCCGTCTGTCAATTGAAGAAAGATTATCAAAAGGCATTCGACATGTATCATATCTGTTTAATGCTATCTCCCGATAACGA
TTTCTCTTTGGTTTATTATATGGGTCAATGCCAGATGGGCTTAAAAAACATTAAAATGGCCACGGAGTTATTTAATACAG
TCGTAACCTATAGTCAAAATGAAAAAATTAAAGAGATGGCTACAACTTATCTTGAACTTTTGACAGCCAATTCCGAAGAG
GAAGTTCAAACAGAGTGA

Protein sequence :
MESANLDLEENKEIASKFERALGMGATLAELHGITPDTLEGVYAYAYNFYEKGRLDEAELFFKFLCIYDFQNYNYLKGYA
AVCQLKKDYQKAFDMYHICLMLSPDNDFSLVYYMGQCQMGLKNIKMATELFNTVVTYSQNEKIKEMATTYLELLTANSEE
EVQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sicA YP_217805.1 surface presentation of antigens; secretory proteins Virulence SPI-1 Protein 2e-27 47
spaT NP_457280.1 unknown function Virulence SPI-1 Protein 2e-27 47
spaT NP_806489.1 hypothetical protein Virulence SPI-1 Protein 2e-27 47
sicA NP_461807.1 secretion chaperone Virulence SPI-1 Protein 2e-27 47
ECs3708 NP_311735.1 hypothetical protein Not tested LIM Protein 6e-34 45
sycB AAS66850.1 SycB Not tested SSR-1 Protein 1e-19 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcSMS35_4018 YP_001745981.1 putative type III secretion chaperone SicA VFG0547 Protein 4e-28 47
EcSMS35_4018 YP_001745981.1 putative type III secretion chaperone SicA VFG0988 Protein 1e-28 42
EcSMS35_4018 YP_001745981.1 putative type III secretion chaperone SicA VFG2451 Protein 1e-28 41
EcSMS35_4018 YP_001745981.1 putative type III secretion chaperone SicA VFG1769 Protein 5e-22 41