Gene Information

Name : EcSMS35_4002 (EcSMS35_4002)
Accession : YP_001745965.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : phage integrase family site specific recombinase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4081597 - 4082760 bp
Length : 1164 bp
Strand : +
Note : identified by match to protein family HMM PF00589

DNA sequence :
ATGGCTCTCACCGATATACAGATCAAACGTGCAAAACCACAAGACAAGCCATACACATTGAACGATGGACAAGGTCTGTC
ATTGCTTATCAATCCCGATGGCTCGAAAGGCTGGCGTTTCCGTTTCCGGTTTGCAGGGAAAGCGCGGTTAATGTCATTTG
GCAGCTACGATTTAGTAAGCCTCGCAGAAGCACGTGAGAAGCGTGATATCGCCCGTAAGCAGGTTGCTAATGGCATTGAC
CCGGTAGAGGAACGCAAAGCTTTAAGACTCGCCCAAAAGCTATCAACAGAAAATTCTTTCGAAGCAATATGTCGAGAATG
GCATACCAACAAAGCTGACCGCTGGACTGTGGCCTATCGAGAAGAAATCATTAAGACATTCGAGCAAGATGTCTTCCCGT
TCATTGGTAAACGTCCTATCAGTGAAATCAAACCATTAGAACTGCTTGAAGTATTACGACGAATCGAAAAACGTGGAGCA
CTAGAGAAAACACGCAAGGTGCGTCAAAGATGCGGTGAGGTTTATCGCTATGCAATCATAACTGGCCGTGCTGAGTACAA
TCCTGCACCTGATTTAGCTATCGCTCTGGCCGTTCCCAAGCAAAAACACCATCCATTTTTATCCGCTGAAGAGTTGCCTC
ATTTTATTCGAGATCTTGAAGCGTATACCGGTAGCATCATCACCAAAAATGCTACGAAGATAGTCATGCTGACTGGTGTA
AGAACGCAGGAGATGCGCTTTGCTACGTGGGAAGAAGTAGACCTCGAAAAAGGTATATGGGAGATACCAGCGGAACGTAT
GAAAATGCGTAGACCTCACATTGTTCCTTTATCTACTCAGGTAGTTGACCTTTTCAAACAGCTCAAACCTATTACCGGCC
ATTACCCTTACATCTTTATTGGCAGGAACAACCGCAGCAAGCCAATCTCAAAAGAAAGTGTTTCACAAGTGATTGAGTTA
ATTGGCTACAAAGGCCGTGCTACAGGTCACGGTTTTCGGCATACCATGTCGACAATATTGCACGAACAAGGGTTTGATAG
CGCATGGATTGAAATACAATTGGCACATGTTGATAAAAACAGAATCCGAGGGACTTACAATCATGCTCAATATCTTGAAC
ATAGAAAAAAAATGATGCAATGGTATTCAGATAAATTATATTGA

Protein sequence :
MALTDIQIKRAKPQDKPYTLNDGQGLSLLINPDGSKGWRFRFRFAGKARLMSFGSYDLVSLAEAREKRDIARKQVANGID
PVEERKALRLAQKLSTENSFEAICREWHTNKADRWTVAYREEIIKTFEQDVFPFIGKRPISEIKPLELLEVLRRIEKRGA
LEKTRKVRQRCGEVYRYAIITGRAEYNPAPDLAIALAVPKQKHHPFLSAEELPHFIRDLEAYTGSIITKNATKIVMLTGV
RTQEMRFATWEEVDLEKGIWEIPAERMKMRRPHIVPLSTQVVDLFKQLKPITGHYPYIFIGRNNRSKPISKESVSQVIEL
IGYKGRATGHGFRHTMSTILHEQGFDSAWIEIQLAHVDKNRIRGTYNHAQYLEHRKKMMQWYSDKLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int AAD44730.1 Int Not tested SHI-2 Protein 3e-138 71
int CAC39282.1 integrase Not tested LPA Protein 5e-140 71
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-140 71
int AAC31482.1 CP4-like integrase Not tested LEE Protein 5e-139 70
int ACU09430.1 integrase Not tested LEE Protein 5e-139 70
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 7e-139 70
ECs4534 NP_312561.1 integrase Not tested LEE Protein 7e-139 70
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 2e-137 70
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 2e-137 70
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-137 70
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 3e-111 58
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 9e-112 55
intA AAB00935.1 integrase A Not tested vap locus Protein 2e-59 42
int AAN62223.1 putative integrase Not tested PAGI-3(SG) Protein 2e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcSMS35_4002 YP_001745965.1 phage integrase family site specific recombinase VFG0783 Protein 3e-139 70
EcSMS35_4002 YP_001745965.1 phage integrase family site specific recombinase VFG0598 Protein 7e-138 70