Gene Information

Name : arsB (EcSMS35_3794)
Accession : YP_001745760.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 3860362 - 3861651 bp
Length : 1290 bp
Strand : +
Note : identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935

DNA sequence :
ATGTTACTGGCGGGCGCTATCTTTGTCCTGACCATCGTATTGGTTATCTGGCAGCCGAAAGGTTTAGGCATCGGCTGGAG
TGCGACACTGGGCGCCGTACTGGCGTTAGTTACTGGCGTGGTCCATCCGGGCGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCGGCGTTTATAGCCGTCATTATCATCAGCTTGCTGCTGGATGAGTCCGGCTTTTTTGAATGGGCGGCG
CTGCACGTCTCACGCTGGGGCAATGGGCGCGGTCGCTTGCTGTTTACCTGGATTGTCCTGCTCGGTGCTGCCGTTGCAGC
TCTGTTTGCCAATGATGGCGCGGCGCTTATTTTGACACCGATTGTCATCGCCATGCTGCTGGCTTTAGGGTTCAACAAAG
GCACTACGCTGGCGTTTGTTATGGCGGCCGGATTCATTGCCGATACCGCCAGCCTGCCGCTTATTGTCTCTAACCTGGTG
AATATCGTTTCGGCAGATTTCTTTAGCCTCGACTTTCGCGAATACGCCTCGGTGATGGTGCCGGTGGATATCGCTGCAAT
ACTGGCTACCCTGGTGATGTTGCATCTCTATTTCCGCAAAGATATTCCGCAGAACTACGACATGGCGCTGCTAAAATCTC
CCGCAGAAGCGGTTAAAGATCCTGCCACCTTCAAAACTGGCGGGGTTGTTTTACTGCTTCTGCTGGTGGGATTTTTCGTC
CTGGAACCGCTCGGCATTCCGGTAAGCGCCATTGCGGCAGTGGGCGCGCTGATATTATTTGTCGTCGCTAAACGCGGTCA
TGCGATTAATACGGGTAAGGTGCTGCGCGGTGCGCCCTGGCAGATTGTCATCTTCTCGCTCGGCATGTATCTGGTGGTTT
ATGGCCTGCGCAATGCCGGATTAACGGAATATCTTTCTGGCGTACTCAACGTGCTGGCGGATAACGGCCTGTGGGCGGCG
ACGCTCGGCACCGGATTCCTCACCGCCTTCCTCTCTTCTATTATGAACAATATGCCGACGGTACTGGTTGGCGCGTTGTC
CATTGATGGCAGCACGGCATCTGGTGTCATCAAAGAAGCGATGGTTTATGCCAACGTAATTGGCTGCGATTTGGGGCCGA
AAATTACACCGATTGGTAGCCTGGCAACGCTGCTCTGGCTGCACGTACTTTCGCAGAAGAATATGACTATCAGCTGGGGA
TATTACTTCCGTACAGGGATTATCATGACCCTGCCGGTGCTGTTTGTGACGCTCGCCGCGCTGGCGCTTCGTCTCTCTTT
CACTTTGTAA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFNKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFSLDFREYASVMVPVDIAAILATLVMLHLYFRKDIPQNYDMALLKSPAEAVKDPATFKTGGVVLLLLLVGFFV
LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTLPVLFVTLAALALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 1e-153 91
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 5e-93 59
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 8e-92 59
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-95 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_001745760.1 arsenical pump membrane protein BAC0578 Protein 2e-157 93
arsB YP_001745760.1 arsenical pump membrane protein BAC0576 Protein 3e-156 93
arsB YP_001745760.1 arsenical pump membrane protein BAC0031 Protein 4e-153 90
arsB YP_001745760.1 arsenical pump membrane protein BAC0577 Protein 7e-152 89
arsB YP_001745760.1 arsenical pump membrane protein BAC0575 Protein 8e-97 59
arsB YP_001745760.1 arsenical pump membrane protein BAC0574 Protein 2e-93 59