Gene Information

Name : EcSMS35_3517 (EcSMS35_3517)
Accession : YP_001745493.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : -
Position : 3596400 - 3597275 bp
Length : 876 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGACCACACTGGCGATTGATATCGGCGGTACTAAACTTGCCGCCGCGCTGATTGGCGCTGATGGGCAGATCCGCGATCG
TCGTGAACTTCCTACGCCAGCCAGCCAGACACCAGAAGCCTTGCGTGATGCCTTATCCGCATTAGTCTCTCCGTTGCAAG
TTCATGCGCAGCGGGTTGCTATCGCTTCAACCGGAATTATTCGCGACGGCAGCCTGCTGGCGCTGAATCCGCATAATCTC
GGTGGATTGCTACACTTTCCGTTAGTCAAAACTTTGGAACAACTTACCGATTTGCCGACCATTGCCATTAACGACGCGCA
GGCCGCAGCATGGGCGGAGTATCAGGCGCTGGAAGGCGATATAACCGAGATGGTGTTTATCACCGTTTCCACTGGCGTCG
GCGGCGGTGTAGTGAGCGGCGGCAAACTGCTTACCGGCCCTGGCGGTCTGGCGGGGCACATCGGGCATACGCTTGCCGAT
CCGCATGGTCCAGTCTGCGGCTGTGGACGCACAGGTTGCGTGGAGGCGATTGCTTCTGGTCGCGGCATTGCAGCGGCAGC
GCAGGGGGAGTTGGCTGGTGCGAATGCGAAAACTATTTTCACGCACGCTGGGCAGGGCGATGAGCAGGCGCAGCAACTGA
TTCACCGTTCCGCACGTACGCTTGCAAGGCTGATCGCTGATATTAAAGCCACAACTGATTGCCAGTGCGTAGTGGTCGGT
GGCAGCGTTGGTCTGGCAGAAGGGTATCTGGCGCTGGTGGAAACGTATCTGGCGCAGGAGCCAGCGGCATTTCATGTTGA
TTTACTGGCGGCGCACTACCGTCATGATGCAGGTTTACTTGGGGCTGCGCTGTTGGCCCAGGGAGAAAAATTATGA

Protein sequence : 
MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQVHAQRVAIASTGIIRDGSLLALNPHNL
GGLLHFPLVKTLEQLTDLPTIAINDAQAAAWAEYQALEGDITEMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGANAKTIFTHAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVG
GSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 2e-38 54
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-26 41
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 2e-26 41
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcSMS35_3517 YP_001745493.1 N-acetylmannosamine kinase VFG1115 Protein 1e-26 41