Gene Information

Name : sitC_2 (EcSMS35_3172)
Accession : YP_001745166.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Virulence
Product : iron/manganese transport system inner membrane protein SitC
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 3252911 - 3253768 bp
Length : 858 bp
Strand : +
Note : identified by similarity to GB:AAT11266.1; match to protein family HMM PF00950; match to protein family HMM PF01032

DNA sequence : 
ATGAACGTGCTACTGGAACCCTTCAGCTATGAATATATGCTCAATGCGATGTGGGTCGCGGCGATGGTCGGCGGTCTCTG
CGCTTTCCTGTCATGCTATCTGATGCTAAAAGGCTGGTCGCTGATTGGCGATGCGCTGTCGCACTCTATCGTCCCGGGTG
TTGCGGGGGCATATATGCTGGGGCTTCCGTTTTCTCTGGGGGCCTTCTTTTCCGGTGGACTGGCTGCGGGCAGCATGCTG
TTTCTTAACCAACGCACTCGCTTAAAAGAAGATGCCATCATCGGCCTGATCTTCTCGTCCTTTTTTGGCCTGGGGCTGTT
TATGGTGTCATTAAACCCGACATCCGTAAATATTCAGACCATCGTCCTGGGCAATATTCTGGCAATCGCTCCGGCGGATA
TCCTGCAACTCACTATCATTGGCATTGTCTCAGTCATCGTGCTGTTTTTCAAATGGAAAGATCTTATGGTGACCTTTTTC
GACGAGAATCACGCCCGTGCTATTGGATTATATCCAGGAAGATTAAAAATCCTCTTCTTCACACTGCTGGCGGTATCGAC
CGTTGCAGCATTGCAAACGGTTGGGGCTTTTCTGGTGATCTGTCTGGTAGTGACCCCTGGCGCAACAGCATGGTTGTTAA
CCGATCGTTTTCCCCGCCTGCTCGTGATTGCTGTAACTATTGGCAGTGTAACCAGTTTCCTCGGCGCGTGGGTCAGTTAC
TTTCTGGACGGAGCGACAGGTGGAATCATCGTGGTGGCGCAGACACTGCTGTTTCTTTTAGCATTTGTCTTTGCACCCAC
CCATGGGCTTTTGGCAAATCGTCAGCGTGCGCATAAGGCGCTGGAGGATCGCTCATGA

Protein sequence : 
MNVLLEPFSYEYMLNAMWVAAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSML
FLNQRTRLKEDAIIGLIFSSFFGLGLFMVSLNPTSVNIQTIVLGNILAIAPADILQLTIIGIVSVIVLFFKWKDLMVTFF
DENHARAIGLYPGRLKILFFTLLAVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLVIAVTIGSVTSFLGAWVSY
FLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRQRAHKALEDRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC NP_461784.1 permease Virulence SPI-1 Protein 6e-90 87
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 5e-90 87
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 5e-90 87
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 4e-90 87
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 6e-90 87

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC_2 YP_001745166.1 iron/manganese transport system inner membrane protein SitC BAC0351 Protein 3e-90 87
sitC_2 YP_001745166.1 iron/manganese transport system inner membrane protein SitC BAC0441 Protein 4e-66 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC_2 YP_001745166.1 iron/manganese transport system inner membrane protein SitC VFG0527 Protein 2e-90 87