Gene Information

Name : sitA_2 (EcSMS35_3170)
Accession : YP_001745164.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Virulence
Product : iron/manganese transport system periplasmic binding protein SitA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 3251173 - 3252087 bp
Length : 915 bp
Strand : +
Note : identified by similarity to GB:AAT11264.1; match to protein family HMM PF01297

DNA sequence : 
ATGCACTCAATAAAAAAATTAACCATGCTCTTGGGGTTCCTCGCCCTCACCTGCTCGATAGCATTTCAGGCGAGTGCAAC
TGAAAAATTCAAGGTCATTACAACATTTACCATCATCGCAGATATGGCCAAAAACGTGGCTGGAGATGTTGCAGAAGTCT
CATCCATAACCAAGCCCGGTGCGGAAATTCATGAGTATCAGCCTACCCCTGGCGATATTAAACGTGCGCAGGGGGCACAA
CTGATTCTCGCCAATGGAATGAATCTGGAATTGTGGTTCCAGCGCTTTTACCAGCATCTCAATGGTGTTCCAGAAGTGAT
TGTCTCTTCGGGTGTGACGCCAGTAGGGATCACCGAAGGACCCTACGAGGGAAAACCTAACCCTCATGCCTGGATGTCGC
CAGATAATGCTTTGATTTACGTCGATAATATTCGTGATGCGTTGATAAAATACGATCCGGCAAATGCAAAAACATACCAA
CGTAATGCCGATACTTATAAAGCCAAGATTACCCAAACCCTTGCCCCCCTGCGTAAGCAGATTGCTGAACTCCCTGAGAA
TAAAAGATGGATGGTCACCAGTGAAGGGGCTTTTTCTTATCTCGCACGCGATTTGGGGCTAAAAGAGCTTTATCTGTGGC
CGATAAATGCCGATCAACAAGGAACACCCCAGCAGGTACGTAAAGTGGTTGATATAGTGAAGAAAAATAATATCCCAGCG
GTATTTAGTGAGAGTACGGTTTCCGATAAACCAGCGCGTCAGGTTGCGCGTGAAACCGGCGCACACTACGGCGGTGTGCT
CTATGTCGATTCCCTGAGCACAGAAAACGGCCCGGTACCTACGTATATCGACCTTCTGAAGGTTACTACCAGTACGCTGG
TGCAGGGAATTAAAGCCGGGAAAAGGGAGAAGTAA

Protein sequence : 
MHSIKKLTMLLGFLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDVAEVSSITKPGAEIHEYQPTPGDIKRAQGAQ
LILANGMNLELWFQRFYQHLNGVPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAKTYQ
RNADTYKAKITQTLAPLRKQIAELPENKRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNNIPA
VFSESTVSDKPARQVARETGAHYGGVLYVDSLSTENGPVPTYIDLLKVTTSTLVQGIKAGKREK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 5e-110 74
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 5e-110 74
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-110 74
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 3e-110 74
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 5e-110 74

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA_2 YP_001745164.1 iron/manganese transport system periplasmic binding protein SitA BAC0349 Protein 2e-110 74
sitA_2 YP_001745164.1 iron/manganese transport system periplasmic binding protein SitA BAC0439 Protein 5e-91 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA_2 YP_001745164.1 iron/manganese transport system periplasmic binding protein SitA VFG0525 Protein 2e-110 74