Gene Information

Name : EcSMS35_3112 (EcSMS35_3112)
Accession : YP_001745129.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : site-specific recombinase, phage integrase family protein
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 3197411 - 3198595 bp
Length : 1185 bp
Strand : +
Note : identified by match to protein family HMM PF00589

DNA sequence : 
ATGGCACTTACAGCCAGACAGGTCGAAACAGCCAGACCTAAAGAAAAAGACTATAAACTCTCTGACGAACGTGGTTTATA
TCTGCTGGTAAAAACCACGGGTGCCCGCTACTGGCGGCTTAAATACCGGATAGCAGGAAAAGAGAAAAAACTGGCCCTCG
GCGTCTATCCCGACGTCTCCCTTGCTGAGGCCAGAATCAAACGCGACGATGCCCGAAAAATCATCTCCGAAGGTGGTGAC
CCGGGCGAAAAGAAGCGAAAGGAAAAACTCACTCAGAAAATCTCTGCCACCAATACGTTCCATGCCCTCGCTACGGAATG
GCACCAGCATAAATCTTTGTCATGGTCTGAAAGTTACGCCAGAAGCGTACTGGAAGCGCTGGATAAAGATATTTTCCCGT
ATCTGGGCAAACGAAGCGTTACGGATATCCTCCCGCTGGAAATGCTGGAAATTCTGCGCCGCATAGAAAAACGTGGCTCG
CTGGAAAAACTTCGTAAGGTGCGTCAATACTGTAATCAGATTTTTCGTTATGCCATCGCCACCGGACGAGCCACTGTCAA
TCCGGCATCTGAACTGACCAGTACGCTGGCGGCGCCAAAAGCTGCACATTTCCCCCACCTGAGAGCAGATGAGCTCCCTG
TTTTTCTCCGGAAGCTCGCTGAGTATCATGGCAGTCCTGTTACCCGCATGGCGACAAATCTGCTGCTTCTGACAGGTCTC
AGAACCATTGAGCTACGGTCCGCTGAATGGTCAGAAATTGATTTTGATAATGCACTGTGGACAATCCCTGAAAGCCGCAT
GAAAATGCGACGTAAACATGTCGTACCACTGTCACGACAGGCCACTGACATTCTGCTGCAGCTCAAAACTTTCTCCGGGC
AATACCGGCTGGTTTTTCCGGGACGTTGTGATATCAACAAGCCAATGAGCGAAGCCAGCATCAATATGGTGCTCAAACGT
ATCGGTTACGATGGCAGGGCAACCGGTCATGGTTTTCGTCACACCATGAGTACCATTCTGCACGAACAGGGCTTTAATTC
TGCCTGGATTGAAATGCAGTTAGCTCATGTGGATAAAAATTCCATCAGGGGTACCTATAATCATGCCCTGTATCTCGATG
GTCGCCGTGAAATGATGCAATGGTACGCTGACTACATTGATTCACTTTCCATCCAGGAGAGTTAA

Protein sequence : 
MALTARQVETARPKEKDYKLSDERGLYLLVKTTGARYWRLKYRIAGKEKKLALGVYPDVSLAEARIKRDDARKIISEGGD
PGEKKRKEKLTQKISATNTFHALATEWHQHKSLSWSESYARSVLEALDKDIFPYLGKRSVTDILPLEMLEILRRIEKRGS
LEKLRKVRQYCNQIFRYAIATGRATVNPASELTSTLAAPKAAHFPHLRADELPVFLRKLAEYHGSPVTRMATNLLLLTGL
RTIELRSAEWSEIDFDNALWTIPESRMKMRRKHVVPLSRQATDILLQLKTFSGQYRLVFPGRCDINKPMSEASINMVLKR
IGYDGRATGHGFRHTMSTILHEQGFNSAWIEMQLAHVDKNSIRGTYNHALYLDGRREMMQWYADYIDSLSIQES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 9e-173 99
int AAD44730.1 Int Not tested SHI-2 Protein 9e-119 63
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-120 63
int CAC39282.1 integrase Not tested LPA Protein 2e-120 63
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 7e-118 63
ECs4534 NP_312561.1 integrase Not tested LEE Protein 7e-118 63
int AAC31482.1 CP4-like integrase Not tested LEE Protein 5e-118 63
int ACU09430.1 integrase Not tested LEE Protein 5e-118 63
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-115 62
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 3e-118 62
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 4e-118 62
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 4e-118 62
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 3e-68 43
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 7e-71 43
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 1e-70 43
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 4e-70 43
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 4e-70 43
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 1e-70 43
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-70 43
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-69 43
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-70 43
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 9e-71 43
int AAL51028.1 CP4-like integrase Not tested LEE Protein 9e-71 43
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-70 43
int-phe AAL60261.1 Int-phe Not tested LEE Protein 9e-71 43
int AAL51003.1 CP4-like integrase Not tested LEE Protein 3e-70 43
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-70 43
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-70 43
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 2e-70 43
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-70 43
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-69 43
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-69 43
int AAK00456.1 Int Not tested SHI-1 Protein 2e-63 42
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 6e-70 42
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-65 42
int CAC81896.1 integrase Not tested LEE II Protein 5e-64 42
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 2e-65 41
unnamed AAT96071.1 site-specific recombinase Not tested T-PAI Protein 5e-55 41
int AAN62223.1 putative integrase Not tested PAGI-3(SG) Protein 8e-52 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcSMS35_3112 YP_001745129.1 site-specific recombinase, phage integrase family protein VFG0783 Protein 3e-118 63
EcSMS35_3112 YP_001745129.1 site-specific recombinase, phage integrase family protein VFG0598 Protein 2e-118 62
EcSMS35_3112 YP_001745129.1 site-specific recombinase, phage integrase family protein VFG0626 Protein 2e-70 43
EcSMS35_3112 YP_001745129.1 site-specific recombinase, phage integrase family protein VFG1693 Protein 7e-71 43
EcSMS35_3112 YP_001745129.1 site-specific recombinase, phage integrase family protein VFG1536 Protein 7e-66 42