Gene Information

Name : nrdF (EcSMS35_2798)
Accession : YP_001744827.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 2878987 - 2879946 bp
Length : 960 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTCTCTCGTATCAGCGCCATCAACTGGAACAAGATATCTGACGATAAAGATCTGGAGGTGTGGAATCGCCTGAC
CAGCAATTTCTGGCTACCAGAAAAGGTGCCACTGTCGAACGATATACCTGCATGGCAGACATTAAGTGTCGTAGAACAAC
AACTAACAATGCGCGTTTTTACTGGCCTGACGCTACTCGACACGCTACAAAATGTTATCGGCGCGCCCTCGCTGATGCCC
GATGCACTCACCCCCCATGAAGAGGCGGTATTATCAAATATCAGCTTTATGGAAGCGGTTCATGCCCGCTCTTACAGTTC
AATTTTCTCGACGCTGTGCCAGACCAAAGATGTCGATGCCGCCTACGCCTGGAGTGAAGAAAACGCGCCGTTGCAGCGAA
AAGCACAGATTATTCAGCAACATTATCGCGGTGATGATCCGCTGAAAAAGAAAATCGCCAGTGTGTTTCTTGAATCTTTT
TTGTTCTATTCCGGTTTCTGGCTGCCGATGTATTTTTCCAGCCGCGGAAAGCTAACCAATACCGCAGACCTGATCCGTCT
GATTATCCGGGATGAAGCAGTCCACGGTTACTACATCGGCTATAAATATCAGAAAAAACTGGAAAAAATCTCCCTGGCAC
AACGTGAAGAGTTGAAGAGTTTCGCCTTCGATTTGTTGCTGGAACTCTATGACAACGAGTTGCAATATACCGATGAGCTG
TACGCCGAAACCCCGTGGTCTGACGATGTAAAAGCGTTTCTCTGTTACAACGCCAATAAAGCGTTGATGAATCTGGGCTA
CGAACCGCTATTTCCCGCAGAAATGGCGGAAGTGAATCCGGCAATCCTCGCCGCGCTTTCGCCGAATGCCGATGAAAATC
ACGATTTCTTTTCCGGTTCAGGCTCTTCATATGTGATGGGAAAAGCGGTCGAAACAGAAGATGAAGACTGGAATTTCTGA

Protein sequence :
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP
DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKKLEKISLAQREELKSFAFDLLLELYDNELQYTDEL
YAETPWSDDVKAFLCYNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 1e-104 67