Gene Information

Name : kdsB (EcSMS35_2202)
Accession : YP_001744252.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2215659 - 2216405 bp
Length : 747 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTGTGGTCATTATTCCCGCGCGCTACGCGTCCACGCGTCTGCCCGGTAAACCATTGGTTGATATTAACGGTAA
ACCCATGATTGTTCATGTTCTTGAACGCGCGCGCGAATCAGGTGCCGAGCGCATCATCGTGGCAACCGATCATGAGGATG
TTGCCCGCGCTGTTGAAGCCGCTGGCGGTGAAGTATGTATGACGCGCGCCGATCATCAGTCAGGAACAGAACGTCTGGCG
GAAGTTGTCGAAAAATGCGCATTCAGCGACGACACGGTGATCGTTAATGTGCAGGGGGATGAACCGATGATCCCTGCGAC
AATCATTCGTCAGGTTGCTGATAATCTCGCCCAGCGTCAGGTGGGTATGGCGACTCTGGCGGTGCCAATCCACAATGCGG
AGGAAGCGTTTAACCCGAATGCGGTGAAAGTGGTCCTCGACGCTGAAGGGTATGCACTGTACTTCTCTCGCGCCACCATT
CCTTGGGATCGTGATCGTTTTGCAAAAGGCCTTGAAACCGTTGGCGATAACTTCCTGCGTCATCTTGGTATTTATGGCTA
CCGTGCAGGATTTATCCGTCGTTACGTCAACTGGCAGCCAAGTCCGTTAGAACACATCGAAATGTTAGAGCAGCTTCGTG
TTCTGTGGTACGGCGAAAAAATCCATGTTGCTGTCGCCCAGGAAGTTCCTGGCACAGGTGTGGATACCCCTGAAGATCTC
GAGCGCGTTCGCGCTGAAATGCGCTAA

Protein sequence :
MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDL
ERVRAEMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-34 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-34 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-34 45