Gene Information

Name : lolD (EcSMS35_2009)
Accession : YP_001744061.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Resistance
Product : lipoprotein transporter ATP-binding subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 2029190 - 2029891 bp
Length : 702 bp
Strand : -
Note : outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone

DNA sequence :
ATGAATAAGATCCTGTTGCAATGCGACAACCTGTGCAAACGCTATCAGGAAGGCAGTGTGCAAACCGATGTACTGCACAA
TGTCAGTTTCAGCGTCGGCGAAGGTGAAATGATGGCGATCGTCGGTAGCTCTGGTTCCGGTAAAAGTACCTTGCTGCACC
TGCTGGGCGGGCTGGATACACCAACCTCCGGCGATGTGATCTTTAACGGTCAACCGATGAGCAAACTGTCTTCGGCGGCA
AAAGCAGAACTGCGCAACCAGAAGCTGGGCTTTATTTATCAGTTTCACCACCTGCTGCCGGATTTTACTGCCCTGGAAAA
CGTGGCTATGCCACTGCTGATTGGCAAGAAAAAGCCCGCTGAAATCAACAGCCGTGCGCTGGAGATGTTAAAAGCGGTGG
GGCTGGGGCATCGTGCGAATCACCGCCCATCTGAACTTTCTGGCGGCGAACGCCAGCGTGTGGCGATTGCCCGTGCGCTG
GTCAATAACCCGCGTCTGGTACTGGCGGATGAACCTACCGGTAACCTCGATGCGCGTAACGCCGACAGCATCTTCCAGTT
GCTTGGGGAATTGAATCGCTTGCAGGGCACCGCCTTCCTGGTGGTTACTCACGACCTGCAACTGGCGAAACGTATGAGCC
GCCAACTGGAGATGCGTGATGGTCGTCTGACGGCGGAACTGAGCCTGATGGGGGCGGAGTAA

Protein sequence :
MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAA
KAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLKAVGLGHRANHRPSELSGGERQRVAIARAL
VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 7e-28 42
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-28 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-28 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 2e-28 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lolD YP_001744061.1 lipoprotein transporter ATP-binding subunit NC_008702.1.4606598. Protein 6e-37 48
lolD YP_001744061.1 lipoprotein transporter ATP-binding subunit NC_012469.1.7686878. Protein 3e-41 45
lolD YP_001744061.1 lipoprotein transporter ATP-binding subunit CP001581.1.gene798.p Protein 8e-37 41