Gene Information

Name : ldcC1 (EcSMS35_0197)
Accession : YP_001742314.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Virulence
Product : lysine decarboxylase, constitutive
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 218861 - 221002 bp
Length : 2142 bp
Strand : +
Note : identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711

DNA sequence :
ATGAACATCATTGCCATTATGGGACCGCATGGCGTCTTTTATAAAGATGAGCCCATCAAAGAACTGGAGTCGGCGCTGGT
GGCGCAAGGCTTTCAGATTATCTGGCCACAAAACAGCGTTGATTTGCTGAAATTTATCGAACATAACCCTCGAATTTGCG
GCGTGATTTTTGACTGGGATGAGTACAGTCTCGATTTATGTAGCGATATCAATCAGCTTAATGAATATCTCCCGCTTTAT
GCCTTCATCAACACCCACTCGACGATGGATGTCAGCGTGCAGGATATGCGGATGGCGCTCTGGTTTTTTGAATATGCGCT
GGGGCAGGCGGAAGATATCGCCATTCGTATGCGTCAGTACACCAACGAATATCTTGATAACATTACGCCGCCGTTCACGA
AAGCCTTGTTTACCTACGTCAAAGAGCGGAAGTACACCTTTTGTACGCCGGGGCATATGGGCGGCACCGCATATCAAAAA
AGCCCGGTTGGCTGTCTGTTTTATGATTTTTTCGGCGGGAATACCCTCAAGGCGGACGTCTCTATTTCGGTCACCGAGCT
TGGTTCGTTGCTCGACCACACCGGGCCACACCTGGAAGCGGAAGAGTACATCGCGCGGACGTTTGGCGCGGAACAGAGTT
ATATCGTCACCAACGGAACATCGACGTCGAACAAAATTGTGGGTATGTACGCCGCGCCATCCGGCAGTACGCTGTTAATT
GACCGCAATTGTCATAAATCGCTGGCGCATCTGTTGATGATGAACGATGTAGTGCCGGTCTGGCTAAAACCAACACGTAA
TGCGTTGGGGATTCTTGGTGGGATCCCGCGCCGTGAATTTTCTCGCGACAGTATCGAAGAGAAAGTCGCTGCTACCACGC
AAGCACAATGGCCGGTTCATGCGGTGATTACCAACTCCACCTATGATGGCTTGCTCTACAACACCGACTGGATCAAACAG
ACGCTGGATGTCCCGTCGATTCACTTCGATTCTGCCTGGGTGCCGTACACCCATTTTCATCCGATCTACCAGGGTAAAAG
TGGTATGAGCGGCGAGCGTGTTGCGGGAAAAGTGATCTTCGAAACGCAATCGACCCACAAAATGCTGGCGGCGTTATCGC
AGGCTTCGCTGATCCACATTAAAGGCGAGTATGACGAAGAGGCGTTTAACGAAGCCTTTATGATGCATACCACCACCTCG
CCCAGTTATCCCATTGTTGCTTCGGTTGAGACGGCGGCGGCGATGCTGCGTGGTAATCCGGGCAAACGGCTGATTAACCG
TTCGGTGGAGCGGGCGCTGCATTTTCGCAAAGAGGTCCAGCGGCTGCGGGAAGAGTCTGACGGTTGGTTTTTCGATATCT
GGCAACCGCCGCAGGTGGATGAAGCCGAATGCTGGCCCGTTGCGCCTGGCGAACAGTGGCACGGCTTTAACGATGCGGAT
GCCGATCATATGTTTCTCGATCCGGTTAAAGTCACTATTTTGACACCGGGGATGGACGAGCAGGGCAATATGAGCGAGGA
GGGGATCCCGGCGGCGCTGGTGGCAAAATTCCTCGACGAACGTGGGATCGTAGTAGAGAAAACCGGCCCTTATAACCTGC
TGTTTCTCTTTAGTATTGGCATCGATAAAACCAAAGCAATGGGATTATTGCGTGGGTTGACGGAATTTAAGCGCTCTTAC
GATCTCAACCTGCGGATCAAAAATATGCTGCCCGATCTCTATGCAGAAGATCCCGATTTCTACCGCAGTATGCGTATTCA
GGATCTGGCGCAAGGGATCCATAAGCTGATTCGTAAACACGATCTTCCCGGTTTGATGTTGCGGGCATTTGATACCTTGC
CGGAGATGATCATGACGCCACATCAGGCATGGCAGAGACAGATTAAAGGTGAAGTAGAAACCATTGCGCTGGAACAACTG
GTCGGTAGAGTATCGGCAAATATGATCCTGCCTTATCCACCCGGCGTACCGCTGTTGATGCCTGGAGAAATGCTGACCGA
AGAGAGCCGCACGGTACTCGATTTTCTACTGATGCTTTGTTCCGTAGGGCAACATTACCCCGGTTTTGAAACGGATATTC
ACGGCGCGAAACAGGACGAAGACGGCATTTACCGCGTACGAGTCCTAAAAATGGCGGGATAA

Protein sequence :
MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY
AFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQYTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI
DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRREFSRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS
PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFNDAD
ADHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSY
DLNLRIKNMLPDLYAEDPDFYRSMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL
VGRVSANMILPYPPGVPLLMPGEMLTEESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGIYRVRVLKMAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 70
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldcC1 YP_001742314.1 lysine decarboxylase, constitutive VFG1670 Protein 0.0 62