Gene Information

Name : EcSMS35_1888 (EcSMS35_1888)
Accession : YP_001743942.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : IS2 transposase orfB
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 1908150 - 1909055 bp
Length : 906 bp
Strand : +
Note : identified by match to protein family HMM PF00665

DNA sequence :
GTGGATAGCGCACGCGCCCTTATTGCCCGGGGATGGGGAGTAAGCTTAGTCAGCCGTTGTCTCCGGGTGTCGCGTGCGCA
GTTGCACGTAATTCTCAGACGAACCGATGACTGGAAAGATGGTCGCCGCAGCCGTCACTCAGATGATACGGATGTGCTTC
TCCGTATACACCATGTTATCGGAGAGCTGCCCACGTATGGTTATCGTCGGGTATGGGCGCTGCTTCGCAGACAGGCCGAA
CTTGATGGTATGCCTGCGATCAATGCCAAACGTGTTTACCGGATCATGCGCCAGAATGCGCTGTTGCTTGAGCGAAAAAC
CGCTGTACCGCCATCGAAACGGGCACATACTGGCAAAGTGGCCGTGAAAGAAAGCAATCAACGATGGTGCTCTGACGGGT
TCGAGTTCCGCTGTGATAACGGAGAAAAACTGCGAGTCACGTTCGCGCTGGACTGCTGTGACCGTGAGGCACTGCACTGG
GCAGTCACTACGGGCGGCTTCGACAGTGAAACAGTACAGGACGTCATGCTGGGAGCGGTGGAACGCCGCTTCGGCAACGA
GCTTCCGGCGTCTCCAGTAGAGTGGCTGACGGATAATGGTTCATGCTACCGGGCTAATGAAACACGGCAGTTTGCCCGGA
TGTTGGGGCTTGAACCGAAGAACACGGCGGTGCGGAGTCCGGAGAGTAACGGCATAGCAGAGAGCTTCGTGAAAACGATA
AAGCGTGACTACATCAGTATCATGCCTAAACCAGACGGGTTAACGGCAGCAAAGAACCTTGCAGAGGCGTTCGAGCATTA
TAACGAATGGCATCCGCATAGTGCACTGGGTTATCGCTCGCCACGGGAATATCTGCGGCAGCAGGCCAGTAATGGGTTAA
GTGATAACAGGTGTCTGGAAATATAG

Protein sequence :
MDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWKDGRRSRHSDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAE
LDGMPAINAKRVYRIMRQNALLLERKTAVPPSKRAHTGKVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHW
AVTTGGFDSETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTI
KRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQQASNGLSDNRCLEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
insD YP_002414033.1 insertion element IS2 transposase InsD Not tested Not named Protein 7e-137 99
unnamed AAL67379.1 transposase-like protein Not tested PAI II CFT073 Protein 5e-119 98
unnamed CAC39284.1 hypothetical protein Not tested LPA Protein 4e-120 97
SF3708 NP_709447.1 IS2 transposase TnpB Not tested SHI-2 Protein 1e-135 97
SF3721 NP_709460.1 IS2 transposase TnpB Not tested SHI-2 Protein 1e-135 97
S4061 NP_839230.2 insertion element IS2 transposase InsD Not tested SHI-2 Protein 6e-136 97
S4050 NP_839218.2 insertion element IS2 transposase InsD Not tested SHI-2 Protein 1e-135 97
tnpF AAD44739.1 TnpF Not tested SHI-2 Protein 8e-118 96
S3189 NP_838472.2 insertion element IS2 transposase InsD Not tested SHI-1 Protein 1e-134 96
SF2985 NP_708759.1 insertion element IS2 transposase InsD Not tested SHI-1 Protein 2e-116 96
ECO111_3773 YP_003236109.1 putative IS2 transposase InsAB Not tested LEE Protein 4e-122 94
aec49 AAW51732.1 Aec49 Not tested AGI-3 Protein 2e-122 85
unnamed CAC39283.1 hypothetical protein Not tested LPA Protein 1e-84 62
c5197 NP_757045.1 transposase insD Not tested PAI II CFT073 Protein 2e-62 60
insD YP_854263.1 IS2 transposase Not tested PAI I APEC-O1 Protein 3e-66 60
insD AAZ04432.1 IS2 transposase Not tested PAI I APEC-O1 Protein 2e-66 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcSMS35_1888 YP_001743942.1 IS2 transposase orfB VFG1732 Protein 3e-137 99
EcSMS35_1888 YP_001743942.1 IS2 transposase orfB VFG0621 Protein 5e-136 97
EcSMS35_1888 YP_001743942.1 IS2 transposase orfB VFG0608 Protein 5e-136 97
EcSMS35_1888 YP_001743942.1 IS2 transposase orfB VFG0649 Protein 7e-117 96