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Name : wzc (EcSMS35_1002) Accession : YP_001743081.1 Strain : Escherichia coli SMS-3-5 Genome accession: NC_010498 Putative virulence/resistance : Unknown Product : tyrosine kinase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG3206 EC number : 2.7.10.1 Position : 1019915 - 1022077 bp Length : 2163 bp Strand : + Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) DNA sequence : ATGACAGAAAAAGTAAAACAACATGCCGCTCCGGTAACGGGCAGTGATGAAATCGATATTGGTCGCCTGGTCGGCACCGT CATTGAAGCGCGCTGGTGGGTAATTGGCATCACCGCCGTATTTGCCCTCTGTGCCGTGGTTTACACCTTCTTCGCCACGC CGATTTATAGTGCCGACGCACTGGTACAAATCGAGCAAAACAGCGGCAATTCGTTAGTGCAGGACATTGGTTCGGCATTA GCCAACAAACCGCCAGCATCGGACGCCGAGATCCAGTTGATTCGTTCGCGTCTGGTGCTTGGTAAAACGGTGGACGATCT CGACCTCGATATTGCAGTGAGCAAAAACACGTTCCCTATTTTCGGTGCGGGCTGGGATCGCCTGATGGGACGCCAGAACG AGACGGTAAAAGTGACCACCTTTAACCGCCCGAAAGAGATGGCGGATCAGGTGTTTACGCTTAATGTGCTGGACGATAAA AACTACACTCTGAGCAGCGATGGCGGCTTTAGCGCCCGTGGGCAAGCGGGCCAGATGCTGAAAAAAGAAGGCGTCACGCT GATGGTTGAAGCCATTCACTCCAGCCCGGGCAGTGAGTTTACCGTCACCAAATACTCCACGCTGGGGATGATCAACCAAC TGCAAAACAGCCTGACGGTAACGGAGAACGGCAAAGACGCAGGCGTACTGAGCCTGACTTATACCGGTGAAGATCGCGAA CAGATCCGCGACATTCTTAACAGCATCGCCCGTAACTATCAGGAACAAAATATTGAGCGCAAATCCGCGGAAGCGTCGAA AAGCCTCGCCTTCCTCGCGCAACAGTTACCGGAAGTACGTAGCCGCCTTGATGTTGCCGAAAATAAATTGAATGCCTTCC GTCAGGATAAAGATTCTGTTGATCTGCCGCTGGAAGCAAAAGCGGTGCTCGATTCGATGGTGAACATCGACGCACAATTG AACGAACTGACCTTTAAAGAAGCGGAAATCTCCAAGCTGTACACCAAAGTTCACCCGGCGTATCGCACGCTGCTGGAGAA ACGGCAGGCGCTGGAAGACGAAAAAGCCAAACTGAACGGTCGCGTAACGGCGATGCCGAAAACCCAGCAGGAGATTGTCC GTCTGACCCGCGATGTCGAGTCTGGGCAGCAGGTCTATATGCAGCTGCTGAATAAAGAGCAGGAGCTGAAAATCACCGAA GCCAGCACCGTCGGCGATGTGCGCATTGTTGACCCGGCAATCACCCAGCCAGGTGTGCTAAAACCGAAGAAAGGGCTGAT TATCCTTGGGGCGATTATCCTTGGCCTGATGCTCTCTATCGTGGCTGTGCTGCTGCGCTCGTTGTTTAATCGCGGCATTG AAAGCCCGCAAGTGCTGGAAGAACATGGCATTAGCGTCTATGCCAGCATCCCGCTGTCGGAGTGGCAGAAAGCGCGCGAT AGCGTCAAAACCATCAAAGGGATTAAACGCTATAAACAGAGCCAGCTACTGGCGGTGGGGAATCCAACCGATCTGGCGAT TGAAGCCATCCGTAGTCTGCGTACCAGTCTGCACTTCGCGATGATGCAGGCGCAGAACAATGTGTTGATGATGACCGGGG TTAGCCCGTCAATCGGTAAAACCTTTGTCTGCGCCAACCTGGCGGCGGTGATTAGCCAGACCAATAAACGGGTGTTGTTG ATCGACTGCGATATGCGCAAAGGCTACACCCACGAGCTGTTGGGCACTAATAACGTTAATGGCCTGTCGGAAATTCTGAT TGGACAGGGCGATATTACTACTGCTGCTAAACCGACCTCTATTGCCAAATTTGACCTGATCCCGCGCGGTCAGGTGCCGC CAAATCCTTCTGAACTGTTAATGAGCGAACGCTTTGCCGAACTGGTGAAGTGGGCGAGTAAAAACTACGACCTGGTGTTG ATTGATACGCCGCCGATTCTGGCAGTGACCGATGCGGCAATTGTTGGTCGTCATGTCGGAACCACGTTAATGGTGGCGCG TTATGCGGTCAACACATTGAAAGAAGTGGAAACCAGTCTGAGCCGCTTTGAGCAAAATGGTATTCCGGTGAAAGGGGTGA TTCTGAACTCCATCTTCCGCCGCGCCAGCGCGTATCAGGATTATGGCTATTACGAATACGAATATAAGTCGGATGCGAAA TAA Protein sequence : MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCAVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSAL ANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQVFTLNVLDDK NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHSSPGSEFTVTKYSTLGMINQLQNSLTVTENGKDAGVLSLTYTGEDRE QIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQL NELTFKEAEISKLYTKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKEQELKITE ASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVAVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKARD SVKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLL IDCDMRKGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSERFAELVKWASKNYDLVL IDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| orf41 | AAO18066.1 | Orf41 | Not tested | TTSS locus | Protein | 1e-155 | 48 |
