Gene Information

Name : strB (EcSMS35_A0129)
Accession : YP_001740011.1
Strain :
Genome accession: NC_010488
Putative virulence/resistance : Resistance
Product : aminoglycoside resistance protein B
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG3570
EC number : -
Position : 99438 - 100268 bp
Length : 831 bp
Strand : +
Note : identified by match to protein family HMM PF04655

DNA sequence :
ATGCCGCCTGTTTTTCCTGCTCATTGGCACGTTTCGCAACCTGTTCTCATTGCGGACACCTTTTCCAGCCTCGTTTGGAA
AGTTTCATTGCCAGACGGGACTCCTGCAATCGTCAAGGGATTGAAACCTATAAAAGACATTGCTGATGAACTGCGCGGGG
CCGACTATCTGGTATGGCGCAATGGGAGGGGAGCAGTCCGGTTGCTCGGTCGTGAGAACAATCTGATGTTGCTCGAATAT
GCCGGGGAGCGAATGCTCTCTCACATCGTTGCCGAGCACGGCGACTACCAGGCGACCGAAATTGCAGCGGAACTAATGGC
GAAGCTGTATGCCGCATCTGAGGAACCCCTGCCTTCTGCCCTTCTCCCGATCCGGGATCGCTTTGCAGCTTTGTTTCAGC
GGGCGCGCGATGATCAAAACGCAGGTTGTCAAACTGACTACGTCCACGCGGCGATTATAGCCGATCAAATGATGAGCAAT
GCCTCGGAACTGCGTGGGCTACATGGCGATCTGCATCATGAAAACATCATGTTCTCCAGTCGCGGCTGGCTGGTGATAGA
TCCCGTCGGTCTGGTCGGTGAAGTGGGCTTTGGCGCCGCCAATATGTTCTACGATCCGGCTGACAGAGACGACCTTTGTC
TCGATCCTAGACGCATTGCACAGATGGCGGACGCATTCTCTCGTGCGCTGGACGTCGATCCGCGTCGCCTGCTCGACCAG
GCGTACGCTTATGGGTGCCTTTCCGCAGCTTGGAACGCGGATGGAGAAGAGGAGCAACGCGATCTAGCTATCGCGGCCGC
GATCAAGCAGGTGCGACAGACGTCATACTAG

Protein sequence :
MPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIKDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEY
AGERMLSHIVAEHGDYQATEIAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSN
ASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPRRLLDQ
AYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00281 YP_008207746.1 Streptomycin 6-kinase Not tested AbaR25 Protein 9e-127 99
BJAB0868_00285 YP_008211611.1 Streptomycin 6-kinase Not tested AbaR26 Protein 9e-127 99
strB AEA34676.1 aminoglycoside resistance protein B Not tested Not named Protein 7e-127 99
strB YP_001800933.1 aminoglycoside-6-phosphotransferase Not tested Not named Protein 9e-127 99
strB AFV47971.1 streptomycin (6) phosphotransferase StrB Not tested AbaR25 Protein 9e-127 99
strB AEZ06048.1 StrB, APH(6)-Id, streptomycin(6) phosphotransferase Not tested Tn6167 Protein 1e-126 99
strB AFV47999.1 streptomycin (6) phosphotransferase StrB Not tested delta-AbaR25 Protein 9e-127 99
ABK1_0257 YP_005512829.1 Streptomycin resistance protein B Not tested AbaR4d Protein 1e-126 99
ABZJ_00265 YP_005524221.1 streptomycin 3''-kinase Not tested AbaR22 Protein 1e-126 99
strB ACK44538.1 StrB Not tested SGI1 Protein 9e-127 99
strB AGK07030.1 StrB streptomycin phosphotransferase Not tested SGI1 Protein 9e-127 99
strB YP_005176179.1 aminoglycoside 6-phosphotransferase protein Not tested ICEPmu1 Protein 1e-126 99
strB AGK07088.1 StrB streptomycin phosphotransferase Not tested SGI1 Protein 9e-127 99
strB AEQ20908.1 StrB, APH(6)-Id streptomycin(6) phosphtransferase Not tested Tn6166 Protein 1e-126 99
strB AFH57206.1 streptomycin resistance protein Not tested AbaR4a Protein 8e-127 99
strB CAJ77026.1 Streptomycin phosphotransferase B Not tested AbaR1 Protein 2e-124 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
strB YP_001740011.1 aminoglycoside resistance protein B DQ464881.1.gene5.p01 Protein 5e-127 99
strB YP_001740011.1 aminoglycoside resistance protein B AF024602.1.gene6.p01 Protein 7e-127 99
strB YP_001740011.1 aminoglycoside resistance protein B NC_010410.6003392.p0 Protein 1e-124 98
strB YP_001740011.1 aminoglycoside resistance protein B AJ313522.gene.p01 Protein 6e-111 90