Gene Information

Name : cmlA (EcSMS35_A0117)
Accession : YP_001740000.1
Strain :
Genome accession: NC_010488
Putative virulence/resistance : Resistance
Product : chloramphenicol acetyltransferase 2
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4845
EC number : 2.3.1.28
Position : 87706 - 88347 bp
Length : 642 bp
Strand : -
Note : identified by match to protein family HMM PF00302

DNA sequence : 
ATGAATTTTACCCGGATTGACCTGAATACCTGGAATCGCAGGGAACATTTTGCCCTTTATCGTCAGCAGATTAAATGCGG
ATTCAGCCTGACCACCAAACTCGATATTACCGCTTTGCGTACTGCACTGGCGAAAACCGGTTATAAGTTTTATCCGCTGA
TGATTTACCTGATCTCCCGGGCTGTTAATCAGTTTCCGGAGTTCCGGATGGCAATGAAAGATAATGAACTGATTTACTGG
GAACAGTCAGACCCGGTCTTTACTGTCTTTCATAAAGAAACCGAAACATTCTCCGCACTGTCCTGCCGTTATTTTCCGGA
TCTCAGTGAGTTTATGGCGGGTTATAACGCGGTAACAGCAGAATATCAGCATGATACCAGGTTGTTTCCGCAGGGAAATT
TACCGGAGAATCACCTGAATATATCATCGTTACCCTGGGTGAGTTTTGACGGATTTAATCTGAATATCACCGGAAATGAT
GATTATTTTTCCCCGGTTTTTACAATGGCAAAGTTTCAGCAGGAAGGTGACCGCGTACTATTACCTGTTTCTGTACAGGT
TCATCATGCAGTCTGTGATGGTTTTCATGCAGCAAGGTTTATCAATACACTTCAGCTGATGTGTGATAACATACTGAAAT
AA

Protein sequence : 
MNFTRIDLNTWNRREHFALYRQQIKCGFSLTTKLDITALRTALAKTGYKFYPLMIYLISRAVNQFPEFRMAMKDNELIYW
EQSDPVFTVFHKETETFSALSCRYFPDLSEFMAGYNAVTAEYQHDTRLFPQGNLPENHLNISSLPWVSFDGFNLNITGND
DYFSPVFTMAKFQQEGDRVLLPVSVQVHHAVCDGFHAARFINTLQLMCDNILK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catA2 ACF06176.1 chloramphenicol acetyltransferase II Not tested Tn5036-like Protein 5e-92 92
cat CAJ77070.1 Chloramphenicol acetyltransferase Not tested AbaR1 Protein 4e-47 46
cat YP_006098370.1 chloramphenicol acetyltransferase Not tested Tn2411 Protein 6e-47 46
cat AAL08441.1 chloramphenicol acetyltransferase Not tested SRL Protein 2e-46 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 CP004022.1.gene799.p Protein 1e-50 47
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 NC_010558.1.6276004. Protein 2e-47 46
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 NC_010410.6002590.p0 Protein 2e-47 46
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 NC_011586.7045194.p0 Protein 2e-47 46
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 NC_010427.6155852.p0 Protein 4e-38 42
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 NC_010426.6155849.p0 Protein 4e-38 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cmlA YP_001740000.1 chloramphenicol acetyltransferase 2 VFG1032 Protein 1e-46 45