Gene Information

Name : TRQ2_0740 (TRQ2_0740)
Accession : YP_001738775.1
Strain : Thermotoga sp. RQ2
Genome accession: NC_010483
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 754585 - 755985 bp
Length : 1401 bp
Strand : +
Note : KEGG: tma:TM0208 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
GTGCGAAGTACAAAGATCGTATGTACAGTCGGACCAAGAACAGACAGCTACGAAATGATAGAAAAGATGATAGACCTTGG
AGTGAACGTCTTCAGAATAAACACCTCACACGGCGACTGGAACGAGCAGGAACAGAAAATACTCAAAATAAAAGATCTGA
GAGAGAAAAAGAAAAAACCCGTAGCCATTCTGATCGATCTTGCGGGGCCGAAGATCAGAACCGGATACCTCGAAAAAGAG
TTTGTGGAATTGAAAGAGGGCCAGATCTTCACTCTCACCACAAAGGAAATACTTGGAAACGAACACATAGTCTCGGTGAA
TCTCAGCTCTCTTCCAAAGGACGTGAAGAAAGGAGACACCATTCTGCTGAGCGATGGAGAGATAGTGCTTGAGGTAATTG
AAACAACCGATACAGAAGTGAAAACAGTGGTGAAAGTCGGTGGAAAGATCACACACAGGAGAGGTGTGAACGTACCGACG
GCCGATCTTTCGGTGGAATCCATAACGGACAGAGACAGAGAATTCATAAAACTCGGAACGTTGCACGACGTTGAGTTTTT
CGCTCTCTCTTTCGTGAGAAAACCAGAGGACGTGCTCAAGGCAAAAGAAGAGATCAGAAAACACGGAAAGGAAATACCTG
TAATCTCCAAAATAGAAACGAAAAAGGCTCTGGAACGTCTCGAAGAGATAATAAAGGTAAGCGATGGAATCATGGTCGCA
CGCGGTGACCTGGGAGTGGAGATACCCATAGAAGAAGTTCCTATCGTTCAAAAAGAAATCATCAAACTCTCCAAGTACTA
CTCCAAACCAGTTATAGTCGCAACTCAAATACTCGAATCGATGATAGAAAATCCGTTCCCCACGAGGGCAGAGGTCACCG
ACATAGCCAACGCCATCTTCGATGGAGCGGACGCCCTGCTCCTCACAGCGGAAACAGCGGTTGGAAAACATCCCCTTGAA
GCCATAAAGGTGCTGAGTAAAGTAGCAAAAGAAGCCGAGAAGAAACTGGAATTCTTCAGAACGATAGAATACGATACCAG
CGACATATCTGAGGCTATATCACACGCCTGCTGGCAGCTCTCTGAATCTCTAAACGCGAAGCTGATCATCACACCTACCA
TATCCGGGAGTACCGCTGTTCGTGTTTCAAAGTACAACGTTTCTCAACCTATCGTGGCTCTGACACCAGAAGAGAGAACT
TACTACAGACTTTCTCTCGTGAGGAAGGTGATACCCGTTCTCGCCGAAAAGTGCTCTCAGGAGCTGGAGTTCATCGAAAA
AGGATTGAAGAAAGTGGAAGAAATGGGTTTAGCAGAAAAAGGGGATCTGGTGGTTCTCACTTCCGGCGTTCCAGGGAAGG
TGGGAACGACGAACACCATAAGGGTGTTGAAGGTGGATTGA

Protein sequence :
MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLREKKKKPVAILIDLAGPKIRTGYLEKE
FVELKEGQIFTLTTKEILGNEHIVSVNLSSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPT
ADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEIPVISKIETKKALERLEEIIKVSDGIMVA
RGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLE
AIKVLSKVAKEAEKKLEFFRTIEYDTSDISEAISHACWQLSESLNAKLIITPTISGSTAVRVSKYNVSQPIVALTPEERT
YYRLSLVRKVIPVLAEKCSQELEFIEKGLKKVEEMGLAEKGDLVVLTSGVPGKVGTTNTIRVLKVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TRQ2_0740 YP_001738775.1 pyruvate kinase VFG0479 Protein 1e-68 42