Gene Information

Name : lysS (TRQ2_1129)
Accession : YP_001739157.1
Strain : Thermotoga sp. RQ2
Genome accession: NC_010483
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1169124 - 1170632 bp
Length : 1509 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGCTGAAAGAGTTCAAAGAACAACGTCTCAATGAGATACAGGAACTTCGTTCTATGGGTATAGAGCCATATCCCTACAA
ATTCGAAAAAGAACTCACAGCCAGGGAAATAAGAGAAAAGTACGACTATCTCCAAGCTGGAGAAGTTCTTGAATCTGAAA
AACTCTCTTTCGCAGGGAGAGTCATGTCGATACGCCACCATGGAAAGACGGCCTTCTTTCACATGAAAGATGACACAGGT
CGAATCCAGGCTTACGTAAGGGCAGATTCTGTTGGAAAGGAAAAAATGGATCTCTTCAAAAGACACGTCAAAATAGGTGA
CTTTATAGGAGTAAGAGGCTTTCCGTTCAAAAGCAAAACCGGAGAGTTGACCATTTACGTTCAAGAATACACGCTTCTGA
GTAAGGCTCTACGTCCCTTGCCCGAGAAGTGGCACGGCATAAAAGATAAGGAAATCATATACAGGCAGAGGTACCTCGAA
CTCATCGTAAGCGACGAGGCTATTGAGAGGTTCAGAAAGCGCTTCAAGGCTGTTCAAGTGATACGGGAATTTCTCAACAG
CAGGGGATTCATCGAGGTGGAAACGCCTATCCTCCATTACGTCACAGGTGGTGCGGAAGCGAGACCTTTTGTGACCCACC
TAAACGTTTTTGATATAGATATGTATCTGAGAATCGCACCGGAGCTTTACCTGAAGAGGTTGATCATCGGCGGTTTTGAG
AAGATATACGAGATAGGAAAGAACTTCAGAAACGAAGGAATATCTTACAAACACAGTCCCGAGTTCACCAGCATAGAAAT
CTACCAGGCTTACGCGGATTACAACGATATGATGGATCTCACTGAAGAACTGATAGTGGAAGTTGTGAAAAGAACATGCG
GCACCTTGAAAATCTCCTACCAGGGCAAGGAGATAGACTTCACACCACCCTGGAAAAGAGTGAGAATGAGAGACTTTCTC
AAAGAAAAACTCGGGGTGGACATCCTCGAAGATCCCGATGAAGTGTTGTTGAAGAAGCTCGAAGAATATGGAGTGGAACT
GGAAATAAAGAACAGAGCACACCTCATAGATAAACTCAGAGATCTGGTGGAAGAAGAACTGGTGAATCCCACCTTCATAA
TCGATCATCCTGTGGTGATTTCCCCTCTTGCCAAAAGACACCGAGAGGATCCTAGACTCACGGAAAGGTTCGAACTCATC
ATATTTGGAAGGGAGATCGCGAACGCGTTCAGTGAGCTGAACGATCCCGTTGATCAATACCAGAGATTTCTCGAACAGGC
GAAAATGAGAGAAGAGGGGGACGAAGAAGCACACATGATGGATCTCGATTTTGTGAGGGCCCTCGAGTATGGAATGCCTC
CCACGGGAGGACTGGGAATTGGTCTTGACAGGCTCTTCATGTTCATCACGGATTCTCCCACAATAAGGGATGTGATTCCC
TTCCCCATTGTGAAACCCAAAAAGTTCGAGGAAGAAGAGGCGGAATTCGAAGGAGGGTTTGAAGAATGA

Protein sequence :
MLKEFKEQRLNEIQELRSMGIEPYPYKFEKELTAREIREKYDYLQAGEVLESEKLSFAGRVMSIRHHGKTAFFHMKDDTG
RIQAYVRADSVGKEKMDLFKRHVKIGDFIGVRGFPFKSKTGELTIYVQEYTLLSKALRPLPEKWHGIKDKEIIYRQRYLE
LIVSDEAIERFRKRFKAVQVIREFLNSRGFIEVETPILHYVTGGAEARPFVTHLNVFDIDMYLRIAPELYLKRLIIGGFE
KIYEIGKNFRNEGISYKHSPEFTSIEIYQAYADYNDMMDLTEELIVEVVKRTCGTLKISYQGKEIDFTPPWKRVRMRDFL
KEKLGVDILEDPDEVLLKKLEEYGVELEIKNRAHLIDKLRDLVEEELVNPTFIIDHPVVISPLAKRHREDPRLTERFELI
IFGREIANAFSELNDPVDQYQRFLEQAKMREEGDEEAHMMDLDFVRALEYGMPPTGGLGIGLDRLFMFITDSPTIRDVIP
FPIVKPKKFEEEEAEFEGGFEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-95 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001739157.1 lysyl-tRNA synthetase VFG1668 Protein 4e-95 45