Gene Information

Name : guaA (Kcr_1130)
Accession : YP_001737559.1
Strain : Candidatus Korarchaeum cryptofilum OPF8
Genome accession: NC_010482
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1139370 - 1140884 bp
Length : 1515 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAATATGCTCATCATTAACTTCGGTGGTCAGTACGCTCATTTAATAGCTAGAAGGATAAGGGATCTTGGCGTCTATTC
GGAAGTGATCCCTTATACGAGAGCGAGTTTGGAGGAAATAATGGCTAAGAGACCATCGGGATTGATACTTTCGGGAGGGC
CTAGCAGCGTTTACGTGCCGGGCTCACCTTCCATAGATCCCAGGATACTGGACCTAGGTATACCGATCCTGGGGATATGT
TACGGCTTCCAGTTGATAGCTAAGATTATGGGTGGAGAGGTCAGGAGGGGCGAGGGGGAGTTCGGCCCAACTAGGGTCAG
GGTGATTCAGGAAGATGAGCTACTCAGTGGTTGGAACGCTGATATAGTCTGGATGAGTCATTCGGATTTCGTTTCGAATC
TACCGGAGGACTTCATCGTAACATCCATTTCTGAGAAAGGTTATCTTAGTTCATTTAAGCATAAGAGTAAGCCGATATAT
GGCGTTCAATTTCATCCCGAGGTGAAGCATACTAGAGGAGGTTCCCTGATCCTGGAGAACTTCATAAGGATTTCCGGAGC
ACAAAAGAACTGGAACGCGGAGAGGATGCTCTCTCTAATTGAGAGTTATCTCGCTAAGGAAATCTCAGGATGCAAGAAAG
TGCTGGCTGCTGTTAGCGGAGGTGTGGATTCCACGGTCTCCACCCTTCTGGCCAGTAGAGTAGCGGGGGACAAAGTCGTT
CCCGTCTTCGTTAACCATGGCCTGCTCAGGAAGGGTGAGGCTGAGAGCGTCCTCTCTTCCCTTAAGAGTATAGGGATCGA
TGTTATTTACGTGGATGCCTCTGAGGAGTTCCTCAGTTCGCTAAAAGGAATCAAAGATTGTGAGAAGAAGAGGGAAATAA
TAGGAGAAATTTTTGCTAGAATATTCTCGGAGATCTCGGAGAGGGAGGGGTGCGATTGCCTCCTCCAGGGAACGCTATAT
CCGGATGTTGTGGAGAGCGGGGCAGAGATAGGAGCTGATAGGATAAAGAGCCATCATAACGTTGCAGGTCTCCCGCCTTG
GTTCAAGGGGAGAGTCTTAGAGCCTTTGAGATACCTCTATAAGGATGAGGTCAGAAAGCTCGCTAAGTACTTGGGAATAC
CGGAGGAGATCGTGAATAAGCACCCATTCCCCGGTCCCGGACTTGCGGTTAGGGTGATAGGTGAGGTTACTGAGGAGAAG
CTTGAGATAGTTAGGGAGGCATCCAGCATAGTTGAGGAGGTGCTTAGGAAAAGAGGTCTATATGATAAGGTTTGGCAAGC
CTTTTCCGTAGTTGGAGATGACAGATGGGTGGGGATCAAGGGAGATTCTAGAGTCGATGGGTATATAGTGACCGTGAGGA
TCGTGGAGAGCGAGGATGCGATGACAGCGGATTGGTTCGCTTTGGATAGGGAGATCATGGAGGAAATATCCAAGAGGATT
TCCTCTATTCCACGAGTCTCCATGGTAACGTATGCAATAACGACGAAACCCCCCAGCACTATCGAGCCCTGTTGA

Protein sequence :
MNMLIINFGGQYAHLIARRIRDLGVYSEVIPYTRASLEEIMAKRPSGLILSGGPSSVYVPGSPSIDPRILDLGIPILGIC
YGFQLIAKIMGGEVRRGEGEFGPTRVRVIQEDELLSGWNADIVWMSHSDFVSNLPEDFIVTSISEKGYLSSFKHKSKPIY
GVQFHPEVKHTRGGSLILENFIRISGAQKNWNAERMLSLIESYLAKEISGCKKVLAAVSGGVDSTVSTLLASRVAGDKVV
PVFVNHGLLRKGEAESVLSSLKSIGIDVIYVDASEEFLSSLKGIKDCEKKREIIGEIFARIFSEISEREGCDCLLQGTLY
PDVVESGAEIGADRIKSHHNVAGLPPWFKGRVLEPLRYLYKDEVRKLAKYLGIPEEIVNKHPFPGPGLAVRVIGEVTEEK
LEIVREASSIVEEVLRKRGLYDKVWQAFSVVGDDRWVGIKGDSRVDGYIVTVRIVESEDAMTADWFALDREIMEEISKRI
SSIPRVSMVTYAITTKPPSTIEPC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-90 47
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-90 47
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-90 47
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-90 46