Gene Information

Name : guaA (SYNPCC7002_A1362)
Accession : YP_001734614.1
Strain : Synechococcus sp. PCC 7002
Genome accession: NC_010475
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1421964 - 1423586 bp
Length : 1623 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGCTGAACGTGACTACGACTCCACTCCAAAAACCGATTGACGCCACCAATACAGGCAATAGTCTTCAACGCCAAATCAT
CGTTATCTTAGATTTTGGCTCCCAATACTCTGAACTAATTGCCAGAAGAATTCGCGAAACGGAAGTTTACTCTGAGGTCA
TTTCCTATCGCACCAGCGCCGAACAATTGCGGCAACTTAATCCCAGCGGCATCATCCTCTCCGGTGGCCCCAGTTCTGTC
TATGACGACTATGCCCCGGCCTGTGACCCTGAAATTTGGAATCTTGGGATTCCTGTCCTTGGGGTCTGCTACGGGATGCA
GCTAATGGTGAAACAACTCGGCGGTACCGTCGAGCGCGCCAAGCACGCAGAGTATGGCAAAGCATCAATCTTTATCGATG
ATCCCACCGATCTGCTGACCAATGTGGAGGAAGGCTCCACCATGTGGATGAGCCACGGGGACTCCTGTGTGCACCTGCCC
GAAGGGTTTGAAATTTTAGCCCATACGGACAATACTCCTTGTGCGGCGATCGCCCACCATGGCCGCCAACTTTACGGGGT
GCAGTTCCACCCAGAAGTGGTTCATTCCCAGGACGGTATGGCCCTGATCCGCAACTTTGTTTATCACATTTGTAAATGTG
AACCCACCTGGACCACAGAAGCCTTCGTTGAAGAAGCAATTCGTGAGATCCGAGCCCGGGTCGGTGATCAACGGGTACTC
CTCGCCCTTTCTGGAGGCGTCGATTCTTCTACCTTGGCCTTTTTGCTCCACCAAGCGATCGGCGATCAACTGACCTGTAT
GTTCATCGACCAAGGCTTTATGCGGAAAGGGGAACCGGAACGCCTTGTGGAAATCTTTGATGAGCAATTTCACATTCCCG
TCGCCTATATCAACGCCCGCGATCGCTTTATCGACAAGCTCAAAGGGGTTACCGATCCCGAAGAAAAGCGCCGCCTCATT
GGCCACGAATTTATCGCCGTCTTCGAGGAAGAATCAAAACGCCTTGGCCCCTTTGATTACCTCGCCCAGGGGACTCTATA
TCCCGATGTAATCGAATCGGCGGATACCAACGTTGACCCCAAAACGGGAGAACGGGTCGCGGTCAAAATCAAGAGTCACC
ACAACGTCGGCGGTTTACCAGAAGACCTGCGTTTTAAATTGGTTGAACCCCTCCGCAAACTCTTCAAAGATGAAGTGCGT
AAGGTAGCAGCCAGCATTGGTTTGCCCGAAGAGATTATTCGCCGTCACCCCTTCCCTGGCCCTGGCCTCGCGATTCGGAT
CATTGGCGAAGTCACCGCAGAACGGTTAAATATTCTCCGGGATGCAGACTGGGTTGTGCGGGATGAAATCAAAAAGCAAG
GGGTTTACAGTGATTTTTGGCAAGCCTTTGCGGTCTTACTACCGATTCGTAGTGTGGGTGTGATGGGCGATAAGCGCACC
TATGCTCACCCCGTCGTACTGCGGATGATTACCAGTGAAGATGGGATGACAGCGGATTGGGCTCGTCCCCCCTATGAGCT
TTTGGAAACCATTTCTAATCGCATGGTGAATGAGGTGAAAGGGGTTAACCGCGTGGTCTATGACATCACTTCTAAGCCTC
CTGGCACCATCGAGTGGGAGTAA

Protein sequence :
MLNVTTTPLQKPIDATNTGNSLQRQIIVILDFGSQYSELIARRIRETEVYSEVISYRTSAEQLRQLNPSGIILSGGPSSV
YDDYAPACDPEIWNLGIPVLGVCYGMQLMVKQLGGTVERAKHAEYGKASIFIDDPTDLLTNVEEGSTMWMSHGDSCVHLP
EGFEILAHTDNTPCAAIAHHGRQLYGVQFHPEVVHSQDGMALIRNFVYHICKCEPTWTTEAFVEEAIREIRARVGDQRVL
LALSGGVDSSTLAFLLHQAIGDQLTCMFIDQGFMRKGEPERLVEIFDEQFHIPVAYINARDRFIDKLKGVTDPEEKRRLI
GHEFIAVFEEESKRLGPFDYLAQGTLYPDVIESADTNVDPKTGERVAVKIKSHHNVGGLPEDLRFKLVEPLRKLFKDEVR
KVAASIGLPEEIIRRHPFPGPGLAIRIIGEVTAERLNILRDADWVVRDEIKKQGVYSDFWQAFAVLLPIRSVGVMGDKRT
YAHPVVLRMITSEDGMTADWARPPYELLETISNRMVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-139 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-140 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-140 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-123 51