Gene Information

Name : guaA (LCK_00589)
Accession : YP_001727866.1
Strain : Leuconostoc citreum KM20
Genome accession: NC_010471
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 613265 - 614812 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCTGAAGTAAATGCCGATAAGGTCCTAGTTTTAGACTACGGTAGCCAATATAACCAATTAATTACCCGCCGCATTCG
TGAGATGGGTGTTTTTTCAGAATTGAAGTCGCGTCATATGACTGCTGAGGAAGTTAAAGCATATAATCCTAAAGCAATTG
TCTTATCTGGTGGGCCAAAGTCAGTGTATGAAACCGATGCTTTCGCGATTGATAATGGTATCTTTGAATTAGGTATTCCT
GTACTGGGTGTTTGCTACGGCATGCAATTGATGGCTCAAAACCTTGGTGGTCAGGTCGAAGCTAATCCTGGTAATGGTGA
ATTTGGCCAAACCGCTCTAAAGAAAACAGAGTCAGCTGGTCGTTTATTTGCGCATACGCCCGAATCGCAAACTGTGTTGA
TGAGTCATTCAGACAATGTTGTTTCCTTACCAGAAGGGTTTGTTGTTGCTGGTGGATCAGACAAAACACCAATTGCGGCA
ATTGCTAATGATGAGCGACGCTTATATGGTGTCCAGTTTCACGCTGAAACGACACTATCTGAACACGGTAAGCAAATTCT
CCAAAACTTTGTATTAGATATTGCACAAGCAGAAGCAAATTGGGACATGAGTGGATTCATTGATGAACAAATTGCCCGAA
TTCGCGAAACTGTGGGTGATAAAAAAGTTTTGTTGGGCTTATCAGGTGGTGTTGATTCATCAGTTGTTGGTGTACTATTA
CATAAAGCTATTGGTAATCAATTAACTTCCATCTTTGTAGATCATGGTCTGCTGCGCAAAAACGAGGCAGAACAAGTCAT
GACAATGATGGGCGACCAATTTGGTTTGAATATCATTAAAGTCGATGCACAAGATCGTTTCCTTTCAAAATTAGCTGGTG
TCACAGATCCTGAACAAAAACGTAAAATCATTGGTAATGAATTTATTGAAGTCTTCAACGATGAAGCAACTAAGTTAAAA
GATATCGATTTCTTAGCACAAGGAACACTTTATACCGATGTTATCGAGTCTGGTACGGATACGGCACAAACAATTAAGTC
TCATCATAATGTTGGTGGGTTGCCAGAAGATATGCAGTTTAAGTTGATTGAACCATTGAACACACTCTTTAAAGATGAAG
TTCGTGAGTTGGGTGAAGCATTGAATATGCCACACGAAATGGTTTGGCGTCAGCCATTCCCAGGTCCTGGCTTAGGTATT
CGAATTTTAGGTGATATTACCGAAGATAAGCTAGAAATCGTCCGTGATTCTGATTGGATTTTGCGTGATGAAATTGCAAA
AGCAGGTCTTGAAGGCGATGTTTGGCAGTATTTTACTGTCTTGACAGGTGTTCGCTCTGTTGGTGTAATGGGCGATTATC
GTACGTATGATTATACAATTGCCATTCGTGCCATCACTTCTGTTGACGGTATGACAGCTGATTTTGCCCAATTACCTTGG
CCATTGCTGCAAAAGATTTCAGCACGTATTGTCAATGAAGTTGGACACATTAATCGTGTCGTCTACGACATTACGGCTAA
GCCACCAGCAACTGTTGAGTGGGAATAA

Protein sequence :
MAEVNADKVLVLDYGSQYNQLITRRIREMGVFSELKSRHMTAEEVKAYNPKAIVLSGGPKSVYETDAFAIDNGIFELGIP
VLGVCYGMQLMAQNLGGQVEANPGNGEFGQTALKKTESAGRLFAHTPESQTVLMSHSDNVVSLPEGFVVAGGSDKTPIAA
IANDERRLYGVQFHAETTLSEHGKQILQNFVLDIAQAEANWDMSGFIDEQIARIRETVGDKKVLLGLSGGVDSSVVGVLL
HKAIGNQLTSIFVDHGLLRKNEAEQVMTMMGDQFGLNIIKVDAQDRFLSKLAGVTDPEQKRKIIGNEFIEVFNDEATKLK
DIDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGEALNMPHEMVWRQPFPGPGLGI
RILGDITEDKLEIVRDSDWILRDEIAKAGLEGDVWQYFTVLTGVRSVGVMGDYRTYDYTIAIRAITSVDGMTADFAQLPW
PLLQKISARIVNEVGHINRVVYDITAKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-161 66
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-160 66
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-161 66
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-120 51