Gene Information

Name : hemC (YPK_4016)
Accession : YP_001722732.1
Strain : Yersinia pseudotuberculosis YPIII
Genome accession: NC_010465
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4428363 - 4429304 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAATTATTCGAATTGCCACACGACAAAGCCCGCTCGCCTTATGGCAAGCACATTATGTTCAACATTTATT
GCAAGCCAATCACCCTGGTCTGCAAATCGAACTGGTCCCAATGGTCACCCGTGGGGATATCATTTTGGATACACCATTGG
CCAAAGTCGGTGGTAAGGGTTTATTTGTCAAAGAATTAGAGCTGGCGCTGCTGGACGGCAGAGCTGATATTGCCGTGCAT
TCGATGAAAGATGTGCCCATTGCTTTCCCCGAAGGGTTGGGTTTAGTCACGATTTGTGAACGTGAAGACCCGCGCGATGC
TTTCGTCTCGTCACATTATACGCATCTGGATGATCTCCCTGCAGGCAGTGTTGTCGGTACCTCCAGCCTGCGCCGCCAGT
GTCAGCTACGCGAACGGCGACCAGACCTGATTATCCGCGATCTACGGGGCAACGTCGGTACCCGCCTTGCCAAACTGGAT
AATGGTGACTATCAGGCTATTATTCTGGCTGTCGCGGGTCTCAAGCGCCTCGGTCTGGAAAACCGAATTCGCTATGCCAT
GTCAGCGGAGGAGTCCCTCCCGGCTGTCGGCCAAGGTGCCGTAGGTATCGAATGCCGTCTGGATGATGGCCATACCCGCC
AGTTGCTGGCTCCGTTGAACCATCGGCACACCGAATTACGGGTCTGTGCGGAGCGGGCAATGAATATTCGCCTTGAAGGG
GGTTGCCAAGTCCCGATCGGTAGCTACGCTGAACTGGAAGGTGATACTTTATGGCTACGGGCGCTGGTGGGAGCACCTGA
TGGCAGCCAAATGATCCGGGGTGAACGCCGTGGTCCGGCGGCAGAGGCTGAGCAGATGGGCATTGAACTTGCCGATGAGT
TGCTATCACGCGGCGCACGAGAAATCCTGGCGGCGGTTTATCTGGATAATCCTGCGCGATGA

Protein sequence :
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVH
SMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYTHLDDLPAGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLD
NGDYQAIILAVAGLKRLGLENRIRYAMSAEESLPAVGQGAVGIECRLDDGHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAREILAAVYLDNPAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-83 62
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-83 62