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Name : YPK_3918 (YPK_3918) Accession : YP_001722636.1 Strain : Yersinia pseudotuberculosis YPIII Genome accession: NC_010465 Putative virulence/resistance : Virulence Product : multi-sensor hybrid histidine kinase Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG0642 EC number : 2.7.13.3 Position : 4315443 - 4318262 bp Length : 2820 bp Strand : + Note : PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: yps:YPTB0311 two-component sensor/regulator DNA sequence : ATGGGCAAAGCATCATCACTTGTCACTCGATTGACATTATTACTGGGCGTCACACTAACCGTTATTTGGTTAATATTAAT CGCAACAACAGCATTCTTTTCATATGAAAATACACGTCAAATATTAATCAATGAGTTAACACATATGGCATCGATGCGGG CAGACTTAAGTAATCACCAGTTTGAAGGAGCTGAACGTGATGCAGCCTCGTTAATAAGCCGACGAGAAAGCCTCCAGAAC ACCTCACCGTTGCCTGAAATATCGATAAAACATTATGATAGCTGCTATATTCCTTTTAATCTGGACAGCTGTAATATTAA CCAACATAAAAATGATCTGTGGATAATTCAAGCGTATGGCACCGCCGGACAAACTTATTATCTCGACAGTTTTATTATCA AACAAAAAGAGGGGATTGTGTTATTTCCACCCCAAAAATCATCGAGTGATTACCTAAATCAACGGCGCAAAGATTTACTT TTGCTCCCCAAATTCCCTACTCACAATAATATCTATTGGGGAGCCCCCACCTATACGCCTCAAGGTGGCTGGCATGTTTC TGTCGCGGTGTGTGATAAAGTGGGCACCTTGGCTGGCTTCGCCTTAAAACTGAATGATCTCATCGCCTATAATCACCCTG TCGAGCAAAGAGACATTAATTTATTGTTGGATAAGAATGGTGAATTATTACCTATTTCCCAGCAAGCAACATCATCAAAT CAACTACATGAAATTCTTAACCAACTCAAAAACAGTAAATTACACGATGGCTGGCAGCAAACTCCCGACTATTTGGTATT ACGCACCCAATTGAAAGGGCCGGGTTGGCAGCAATTAGTTATTTATCCACGAATAGGCTTTGCCTGGGAGGCACTGAAAC CCGCCTTATATCAACTCCCTTTCGCTCTGGTTATTTTGCTGTTACTCACGTCAGTGCTGTCACTGCTGCTGCGATATTAT CTGGCGATCCCTTTGTGGAATTTCATCAATATCATTGGCGCTACCGGGCCACAGGCAATGGAACCCCGACTTCCCATAAA CCGAATAGATGAATTAGGGCATATTGCCCGCGCTTACAATAACTTACTGGATACGTTGAACGAACAATATGACACCTTAG AAATGAAAGTGAAGGAGCGTACTCTGGCTCTGGCAAAAGCCAAACGAGCTGCTGAGCAGGCTAACCGCCGTAAAAGCGAC CATCTGACCACGATAAGCCATGAAATCCGTACACCGCTCAACGGGGCGTTGGGGGCGGTTGAATTATTACAAAATACACC ACTGGATGCTGGCCAAATGAGGTTAGCGGAAACGGCTCACCAATGTTCGTTGTCACTGCTCGCGATCATTAACAACCTGT TAGATTTTTCACGTATTGAATCAGGGCAAATGACACTGTCGCTGGAGAAAACGGCCCTACTGCCTTTACTGGATCAGGCG ATGTTAACCATTCATAGCCAGGCACTGAGTAAGTCATTAGCGCTGTCCACGTTTATCAGTGCCGATATCCCGCTGGAACT TGAGCTGGATACACTGCGCTTAAGACAGATTCTGGTTAATTTATTAGGTAATGCCGTTAAATTCACACCACAGGGCCGTA TTCAACTCAGGGTCAGGCGTCAAAACCAAACGCTTTGTTTTACCGTTGAGGACACCGGTTGTGGTATTGACGTGCAACAC CAACAAACAATATTCCAACCTTTTATGCAGACCAGTGACCATGAACAAGGAACGGGTTTGGGGCTGGCTATCGCAGATAA TCTGGCCAAAATGATGGGAGGGCACCTGACAGTATTCAGTGAACCGGGTCAAGGTAGTTGTTTTTCATTATGCCTCCCCT TCAATGCAATCACCCCACCCATGCCTTTTCATGGCGAGCTATTCGCACCACAGCGCTTACACGCCCAATTATCAGCCTGG GGCATGACCTGCCAGCCAGAATTAGCTAATCAGCCATCACGGTACTTTGTGGATAACGCATTGTGTTACTTGCCCGGCCG GTTATACGCCAACCTGAAGCAATATCTACAAGGTGCTGAGACTGAGGTGCTAAAGAGCCTTCCGCTGCAACCTTGGCAAA TGCACATTCTGCTGGTTGATGACTCCGAAACGAATCGCGATATTACCGGAATGATGTTGCAGCAACTGGGACATCAGGTC ACGCTGGCAGACAGTGGCACAACCGCATTGGCGATTGGCCGCCAACACCGTTTCGATTTAGTGCTAATGGATATTCGAAT GCCTGTCCTGGACGGGCTGGCCACCACAGCACGCTGGCGTCATGATCCGGCGAACATTGATAGCCACTGCATGATCACCG CCCTGAGCGCCAATGCCAGCCCGGATGAGCAAATCAAAACCAGTCAGGCGGGGATGAACCACTACCTTTCCAAGCCTGTC ACCCTCGGCCAATTGGCTGAAATGTTAGATCTGACCGCACAATTCCAACTTGAACGTGGGGTCGATCTATCGCCACAACT CTCCGAGCCTCAGCCATTACTGGATCTCGCGGATAGCGCGTTGTCCCTGAAACTTTATCAATCACTGCAAGTATTAATTC AGCAGGCCAAAGACGCTATTGAGAACTTGCCCGTATTATCCCATACGCTTCACACCATAAAAGGCTGTGCCGGGCAAGCT GGGCTAATTGAATTACAAGATGCGGTCATTCAATTAGAACACGCTCTCGATACTCATGAAACGCTGACACAGCAAGATAT CATTCAACTTGATGAAATAATTCATGTGCTGCTACAGCCCCCCACTACCTGCGAATCCACGTTTATCATCAGCCAGGGCC AGTCCCTTATGGTTAAATAA Protein sequence : MGKASSLVTRLTLLLGVTLTVIWLILIATTAFFSYENTRQILINELTHMASMRADLSNHQFEGAERDAASLISRRESLQN TSPLPEISIKHYDSCYIPFNLDSCNINQHKNDLWIIQAYGTAGQTYYLDSFIIKQKEGIVLFPPQKSSSDYLNQRRKDLL LLPKFPTHNNIYWGAPTYTPQGGWHVSVAVCDKVGTLAGFALKLNDLIAYNHPVEQRDINLLLDKNGELLPISQQATSSN QLHEILNQLKNSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRIGFAWEALKPALYQLPFALVILLLLTSVLSLLLRYY LAIPLWNFINIIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLEMKVKERTLALAKAKRAAEQANRRKSD HLTTISHEIRTPLNGALGAVELLQNTPLDAGQMRLAETAHQCSLSLLAIINNLLDFSRIESGQMTLSLEKTALLPLLDQA MLTIHSQALSKSLALSTFISADIPLELELDTLRLRQILVNLLGNAVKFTPQGRIQLRVRRQNQTLCFTVEDTGCGIDVQH QQTIFQPFMQTSDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCFSLCLPFNAITPPMPFHGELFAPQRLHAQLSAW GMTCQPELANQPSRYFVDNALCYLPGRLYANLKQYLQGAETEVLKSLPLQPWQMHILLVDDSETNRDITGMMLQQLGHQV TLADSGTTALAIGRQHRFDLVLMDIRMPVLDGLATTARWRHDPANIDSHCMITALSANASPDEQIKTSQAGMNHYLSKPV TLGQLAEMLDLTAQFQLERGVDLSPQLSEPQPLLDLADSALSLKLYQSLQVLIQQAKDAIENLPVLSHTLHTIKGCAGQA GLIELQDAVIQLEHALDTHETLTQQDIIQLDEIIHVLLQPPTTCESTFIISQGQSLMVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| YPO0256 | YP_002345336.1 | two-component sensor/regulator | Not tested | Not named | Protein | 0.0 | 99 |
| spiR | AAC44299.1 | SpiR | Virulence | SPI-2 | Protein | 6e-142 | 47 |
| ssrA | NP_456136.1 | putative two-component sensor kinase | Virulence | SPI-2 | Protein | 3e-149 | 45 |
| ssrA | NP_805063.1 | two-component sensor kinase | Virulence | SPI-2 | Protein | 1e-149 | 45 |
| ssrA | NP_460357.1 | sensor kinase | Virulence | SPI-2 | Protein | 7e-149 | 45 |
| ssrA | YP_216400.1 | secretion system regulator:sensor component | Virulence | SPI-2 | Protein | 9e-150 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| YPK_3918 | YP_001722636.1 | multi-sensor hybrid histidine kinase | VFG0493 | Protein | 3e-149 | 45 |
