Gene Information

Name : YPK_3642 (YPK_3642)
Accession : YP_001722362.1
Strain : Yersinia pseudotuberculosis YPIII
Genome accession: NC_010465
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 4018908 - 4021994 bp
Length : 3087 bp
Strand : -
Note : PFAM: acriflavin resistance protein; KEGG: ypi:YpsIP31758_3512 transporter, AcrB/AcrD/AcrF family

DNA sequence :
ATGAAGCTGACTGATAATTTTATCAATAATAATACCCGTATCTGGCTAACGATTCTGTTGCTAGGTATTGGTGGCATTAT
TGCCTATCTCAATATAGGCAGGCTGGAAGACCCGGCTTTTACCATCAAAACCGCGGTCGTTGTCACCCGCTATGATGGCG
CATCGGCACAACAGGTTGAAGAAGAAGTCACGCTACCGTTGGAGAATGCCATTCAGGAACTCTCCTATGTGGATGACGTA
ACCTCCATTTCCAGTGCCGGTTTATCGCAGATAACCATTAATATTCGTGCGCAATACGGCGCGAATGAGTTACCGCAAAT
CTGGGATGAGCTGCGGCGTAAAATTAGCGATAACAGTGTTCGCCTACCACCAGGGGCCAGTGCCCCCATGGTCAACGATG
ATTTTGGCGATGTTTACGGTTTCTTCTTCTCACTGACCGGTGACGGCTACAGTAATCAGGATCTGCGTAATTTTGCCGAG
CAATTGCGGCGTGAATTAGTGTTGGTGCCCGGTGTGGGTAAAGTCGGCATCGTGGGTATTTTACCGGAAGAAGTTCAGGT
AGAAATTTCCCGTGCGCAGATGACGGCCGCGGGTATTACACCGCAGCAGCTATCCGACTTGCTGAGTCGCCAAAACGTCG
TGTCCGATGCAGGCCAGTTGCAGGTGGGCAGTGAGTCGATTCGCTTGCACCCGACTGGCGAATTCCAAAGCGTACAAGAG
CTGGGGAATTTACTGGTCAGCCAACCCGGTAGCCCAAAAAGTGTCTATCTGCGCGATATTGCCACGGTAACCCAAGGCTT
TGGTCATTCACCGACCAATATTTATCGCGCGAACGGTCAACCGGCATTGGCGTTAGGGATCTCGTTTGCTCCCAATGTTA
ACGTGGTAAATGTTGGGAATGCGATTAAATCCCGTCTGGCGCAGCTTGAAGGTGAGCGCCCGTCCGGGATGCATATCAAT
GTGTTCTACGATCAGTCTAAGGAAGTTGAAGGTGCGGTTAACGGCTTCATTCTTAACTTCCTGCTGGCACTGTTGATTGT
TGTCGTTACCCTGCTGATCTTTATGGGGGTACGCAGCGGCGTGGTTATTGCCATCTCGCTGGCACTTAACGTGCTCGGAA
CGTTGCTCATCATGTGGCTGTTTAACATCGAGCTACAGCGGGTATCGTTAGGGGCGCTGATCATTGCGCTGAGTATGCTG
GTGGATAACGCCATCGTGGTGGTGGAAGGGGTGGTCGTTGGGCGTCAGCGCGGCGATAGCATTTCTACTGCTATCGGTAA
TGTGGTGAAACGCTCGAAGATGCCGTTGCTGGGTGCGACCATTATTGCCATTTTGGCCTTTGCGCCTATCGGCCTGTCCA
ATGATGCTACCGGCGAATATTGTAAGTCGCTATTCCAGGTGTTGCTCATCTCGTTAATGTTGAGCTGGATCACTGCGTTA
ACGTTAACACCGGTGTTTGCCAAGTGGGCATTCCAGAACCAAAAACAGCCTGAAGCTGATGCGGATAAGCCGGTTAAACA
ACCGTATGACGGCTGGTTATTCCGCTATTATCGGGTGGTGTTGAATAAATTACTGCAACACCGCAGTATTACATTGGTGC
TCTTGGCCGCGTTATTAGTGGCGTCGGTTATCGGTTTTGGTCATGTTCGACAGAGCTTCTTCCCGCCTTCTAACACACCA
ATCTTCTTTGTGGATATTTGGCTGCCTTATGGTACGGATATCAGCTACACCGAAGATATTGCAGCCAAAATTGAACAGCA
TATCAAGCAGCAAAAAAATGTAGCGGATACCATGACAACCATAGGTCAGGGCGCAATGCGCTTTATGCTGACCTACAATG
GTCAACGTCATTATCCTAACTATGCGCAGGTGATGGTCCGTACTGAGCAACTGGAGCAAATACCGGGCTTGATTGATGAA
ATCGAGTCATATATGCATGACGAATATCCGCAGGTTGATGCGCAGATCAAACGCATCATGTTCGGGCCATCAAACAACAG
TTCTATTGAAGCCCGCTTTATCGGCCCCGATCCAGATGTGCTACGCACCTTGGCAGCCCAGGCGGAACAGGCGATTATCG
CTGACCCAATGGCCGATGGTGCAAGGCATGACTGGCAGGATCGTAGCAAGATGATCCGGCCACAATTCTCCGATTATCTG
GGCCGCGAGTTGGGGGTCGATAAACGCGAGGTGGATGGTACGTTGCGCATGAGTTTTGGTGGCTTGCCGGTTGGGTTATA
CCGCGATGGTACCCGCCTGATACCTATTGTCCTACGCACACCGGACTCTGAGCGGCTCAATGCTGAGCGGTTGAACGATG
TGATGGTCTGGAGCCAGGCGCGCCAAGCCTTTATCCCGATCGACAACGTGGTCACCAGTTTTGAAACCGAGTGGGAAGAT
CCACTGATTATGCGTCTGGATCGTAAGCGGACACTGACGGTACAAACGGATCCAACCCATCAGGGCGGTGAGACCTCTTC
CGAGTTGTTGCAACGGATCAAGCCGGGCGTTGAAGCCATTACCTTGCCACGGGGCTATGAACTGGAGTGGGGCGGCGATT
ACGAAAGTACCAAAGAAGCACAGCGGGGTATTTTCATTAGCTTGCCGATCGCGTTTCTGCTTATGTTTGTTGTGACCGTG
CTGATGTTTAGCTCGGTGCGTAATGCACTGGCTATTTGGCTGACGGTACCACTGGCATTAATTGGTGTGACCTTCGGCTT
CCTACTGACGGGGATTCCGTTCGGCTTTATGGCCTTGCTGGGGTTATTAAGCTTGAGTGGGATGTTGATCCGTAACGGTA
TTGTACTGGTCGAAGAGATTGGTCTACAGCGGCAAGAGAAACCGTTGCGTGAGGCGATTATCGATGCTTCCACCGCGCGT
TTACGGCCTATCATGCTGACCGCATTTACCACCGTGTTGGGGCTGGCTCCGCTGCTGAGCGATGCCTTCTTCCAGAGTAT
GGCGGTGGTGATTATGTTTGGCTTGGGCTTCGCGACAGTACTGACATTGCTGGTACTGCCAGTGATTTACAGCAGTATGA
ATCCAGAGCCTAAAGAAAAGATCCACGATGAGCCAGTGAGTGAATAA

Protein sequence :
MKLTDNFINNNTRIWLTILLLGIGGIIAYLNIGRLEDPAFTIKTAVVVTRYDGASAQQVEEEVTLPLENAIQELSYVDDV
TSISSAGLSQITINIRAQYGANELPQIWDELRRKISDNSVRLPPGASAPMVNDDFGDVYGFFFSLTGDGYSNQDLRNFAE
QLRRELVLVPGVGKVGIVGILPEEVQVEISRAQMTAAGITPQQLSDLLSRQNVVSDAGQLQVGSESIRLHPTGEFQSVQE
LGNLLVSQPGSPKSVYLRDIATVTQGFGHSPTNIYRANGQPALALGISFAPNVNVVNVGNAIKSRLAQLEGERPSGMHIN
VFYDQSKEVEGAVNGFILNFLLALLIVVVTLLIFMGVRSGVVIAISLALNVLGTLLIMWLFNIELQRVSLGALIIALSML
VDNAIVVVEGVVVGRQRGDSISTAIGNVVKRSKMPLLGATIIAILAFAPIGLSNDATGEYCKSLFQVLLISLMLSWITAL
TLTPVFAKWAFQNQKQPEADADKPVKQPYDGWLFRYYRVVLNKLLQHRSITLVLLAALLVASVIGFGHVRQSFFPPSNTP
IFFVDIWLPYGTDISYTEDIAAKIEQHIKQQKNVADTMTTIGQGAMRFMLTYNGQRHYPNYAQVMVRTEQLEQIPGLIDE
IESYMHDEYPQVDAQIKRIMFGPSNNSSIEARFIGPDPDVLRTLAAQAEQAIIADPMADGARHDWQDRSKMIRPQFSDYL
GRELGVDKREVDGTLRMSFGGLPVGLYRDGTRLIPIVLRTPDSERLNAERLNDVMVWSQARQAFIPIDNVVTSFETEWED
PLIMRLDRKRTLTVQTDPTHQGGETSSELLQRIKPGVEAITLPRGYELEWGGDYESTKEAQRGIFISLPIAFLLMFVVTV
LMFSSVRNALAIWLTVPLALIGVTFGFLLTGIPFGFMALLGLLSLSGMLIRNGIVLVEEIGLQRQEKPLREAIIDASTAR
LRPIMLTAFTTVLGLAPLLSDAFFQSMAVVIMFGLGFATVLTLLVLPVIYSSMNPEPKEKIHDEPVSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 7e-167 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPK_3642 YP_001722362.1 acriflavin resistance protein BAC0428 Protein 0.0 52
YPK_3642 YP_001722362.1 acriflavin resistance protein BAC0519 Protein 0.0 51
YPK_3642 YP_001722362.1 acriflavin resistance protein BAC0526 Protein 0.0 48
YPK_3642 YP_001722362.1 acriflavin resistance protein BAC0425 Protein 3e-167 41