Gene Information

Name : fliI (YPK_2394)
Accession : YP_001721124.1
Strain : Yersinia pseudotuberculosis YPIII
Genome accession: NC_010465
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2628900 - 2630318 bp
Length : 1419 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGCCCCCCCGCCTCAGCCGCTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCAGCCAAACGACAACAATCCGCCG
TTATGGCCGCTTGACCCGCGCCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTGCCGTTAGGGGCGACCTGTCTGA
TTGAGCGCCATAATGGCGGTGAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAACGGTCAGCATCTGTTTCTTATG
CCTTTGGAAGATGTGGAAGGTATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCACCAGCGGCACGTCTGCCAGTAA
ACAGTCAATTTCTAGTAAACAATCAATTCCCAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAGTTAT
TGGGCCGGGTATTGGATGGCAGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACTGATT
ACACCACCGATAAACCCTTTGCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCTTGTT
GACGGTCGGGCGCGGCCAGCGGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATGGCCC
GTTACACACAGGCTGACGTGATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAATATT
CTCGGGGCTGAAGGCCGTGCCCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAGGTGC
CGCCTATGCCACCCGTATTGCCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACCCGCT
ATGCCATGGCGCAACGTGAAATCGCGCTGGCTATCGGCGAGCCTCCCGCGACCAAAGGTTATCCGCCCTCCGTCTTCGCC
AAATTACCGGCACTGGTTGAACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACCGCATTTTATACCGTCCTCAC
CGAAGGTGATGATCAGCAAGATCCTATTGCTGACTCTGCGCGCGCCATCCTCGATGGCCATGTGGTGCTATCTCGCCGCT
TGGCTGAATCCGGTCACTATCCGGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACCTCGTTAATCGATGACGAC
CATTACAGCCGGGTGCGCCAGTTTAAACAACTGTTTGCCAGTTATCAGCGTAACCGCGATTTGGTCAGTGTCGGGGCTTA
TGCTGCGGGCAGTGATCCCTTATTGGACAAAGCGATTGCCCTGTACCCGCAGATGGAGGCTTTCTTGCAGCAAGGCATGT
TTGAGCGCAGCAGTTTTGACGATGCCTGCCAGCATTTGAAGGGTTTATTTCCCGGCTAA

Protein sequence :
MPPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLM
PLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLI
TPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENI
LGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFA
KLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDD
HYSRVRQFKQLFASYQRNRDLVSVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDDACQHLKGLFPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-70 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-67 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-68 48
escN AAK26715.1 EscN Virulence LEE Protein 1e-68 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-69 48
escN AAL57542.1 EscN Virulence LEE Protein 1e-68 48
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-69 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 8e-69 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-65 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-65 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-71 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-71 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-68 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-68 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-68 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-66 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-66 47
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-67 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-68 47
escN AAC38383.1 EscN Virulence LEE Protein 4e-68 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-68 47
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 8e-61 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 8e-61 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-76 45
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-76 45
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-76 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-75 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-73 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-73 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-76 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-76 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-76 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-57 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-57 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-57 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-57 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-57 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-70 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-56 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_001721124.1 flagellum-specific ATP synthase VFG2331 Protein 0.0 92
fliI YP_001721124.1 flagellum-specific ATP synthase VFG2499 Protein 1e-142 67
fliI YP_001721124.1 flagellum-specific ATP synthase VFG1254 Protein 9e-119 58
fliI YP_001721124.1 flagellum-specific ATP synthase VFG0048 Protein 4e-75 52
fliI YP_001721124.1 flagellum-specific ATP synthase VFG0192 Protein 2e-77 49
fliI YP_001721124.1 flagellum-specific ATP synthase VFG0730 Protein 2e-68 47
fliI YP_001721124.1 flagellum-specific ATP synthase VFG0812 Protein 1e-68 47
fliI YP_001721124.1 flagellum-specific ATP synthase VFG2459 Protein 2e-57 45
fliI YP_001721124.1 flagellum-specific ATP synthase VFG0555 Protein 8e-58 43
fliI YP_001721124.1 flagellum-specific ATP synthase VFG0390 Protein 1e-72 42
fliI YP_001721124.1 flagellum-specific ATP synthase VFG2144 Protein 3e-79 42
fliI YP_001721124.1 flagellum-specific ATP synthase VFG1778 Protein 3e-55 41