Gene Information

Name : YPK_1474 (YPK_1474)
Accession : YP_001720220.1
Strain : Yersinia pseudotuberculosis YPIII
Genome accession: NC_010465
Putative virulence/resistance : Virulence
Product : type VI secretion ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1629626 - 1632283 bp
Length : 2658 bp
Strand : +
Note : KEGG: ypi:YpsIP31758_1362 Clp protease-associated protein ClpB; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain pro

DNA sequence :
GTGGCTATTACAAGGAAACATCTCTTCGGCAAGCTGGACGCCACTCTTTTCAAAGGTATTGAAAGCGCAACAACGATTTG
TAAATTACGCGGCAATCCTTACGTAGAGTTAGTTCACTGGTTGAATCAGCTTTGGCATCAGGAAGATAACGACCTTAAGC
AGATTATTCGGTATTTTGCGGTGGATGTGGATGCCTTTGAGCGTGAGCTGGCTCAGGCACTTGCGAAGTTACCTGTCGGG
GCAACTAGCATTTCAGATTTTTCGTATCATATTGAGTTGGCCACGGAACGGGCTTGGATCTATGCCAGCCTGGAGTGTTT
AGATACCCGTATCCGGAGTGGACACCTGCTGCTTGCGCTATTAACAACAATGGAACTGCGGAGAGCTTTCTTTGCGATTG
CGCCAAGCATGGAAAAAATTCCATTAGAGCATTTAAGCAAAGATTTGAACTTCATTACGCAGGCATCACCAGAAGCGAAT
GAAGCAGCCAGTGATGGCAGCCCGTTGTACGATGGAGCTTTACCTGGCGAAGCCAGTAATGCCATCGGTGCGGCAAAAAG
TGGTGGCACACTGGCTCAATACACCACAGACCTCACGGCATTAGCACGTGAAGGCAAGATAGATCCGGTATTGGGACGTA
ATCACGAAATCAACACAATGGTTGATATTCTCTTGCGCCGTCGGCAGAACAACCCATTACTGACCGGTGACGCAGGGGTG
GGTAAAACCGCCATTGTTGAAGGGCTAGCATTGGCCATTGCTGCAGGCTCAATGCCGCCAGCATTAAGCCAGGTAAGCCT
GTTGTCATTAGATATTGTGGCGCTCTCAGCGGGTGCCAGCATGAAAGGTGAATTTGAAGCGCGCCTGAAGAGTGTCTTGG
ATGAAGCAATCGCGGCAGAAAAGCCCGTTATTTTGTTTATCGATGAAGTCCACACACTTATTGGCGCGGGTGGCAATGCC
GGGACCGGCGATGCGGCGAACTTATTGAAACCTGCATTGGCGCGTGGCCAATTACGTACCATTGGTGCGACAACGTGGAG
CGAGTTCAAGCGTCACATTGAGAAGGATCCGGCACTCACCCGTCGTTTCCAAGTACTTCAAGTTGATGAGCCCGATGAGA
ACACGGCGATCTCCATGTTACGGGGCCTGATACCTGCGCTAGAAAAGCACCATGGCGTGTGGATTATGGACGAAGCCTTA
CAGGCGGCAGTACGGTTGTCTCATCGTTATATCCCTGCGCGTCAGTTGCCGGATAAAGCGATAAGTCTGCTTGATACGGC
TTGTGCCCGGATCGCTGTTGCACAGCATTCACAACCAATAGAGTTGCAGCACTTAACCTTCCAGAGTGAGACCGCGCAAA
CTGAGCTGGTTTCCTTAGAGAAAGCGCGGCACTTTGGTAAAGCGCAGGATGCGCGTACTGAGCAGTTGAAAACATCCATT
GCTGAACATGGCGAGGCTGCAGATAAACTTGATCAGCGTTGGCAGGCAGAACGCGAATTGGTATCAGCGATTACGACCAT
AAGAACCGCACTTTATGACTTGGTTTCTCAGCCAGAGCCTGATGAGGAAAAACGTCGGGCTTATCAAGCGCAATTAGTCC
AGTTGGAAGCGCAGCTTTCTCAGGTTCGCACTTCACTGCCGTTAGTGCAGACAGAAGTCAACGCTGAAGTGATCGCCAGT
ATCGTTGCAGATTGGACCGGCATCCCGGTTGGGCAAATGCTCAAAGACGATATTCGGGCGGTAATGGAGTTGCCACAGCG
CCTTGAAGCACGTGTTATTGGTCAGCCCCATGCATTGATGCAACTGGGTGAGAATATTATGACCGCACGCGCCGGTCTGT
CAGACCCAAGGAAACCATTGGGGGTCTTTATGTTAGTGGGGCCTTCAGGTGTGGGTAAAACAGAGACGGCCTTAGCGATT
GCCGAGAGCATGTATGGTGGTGAACAGAATATGATCACTATCAATATGAGCGAATATCAGGAATCGCATACCGTTTCCTC
TTTAAAAGGTTCTCCACCGGGATATGTTGGATACGGTGAAGGCGGTGTATTAACGGAAGCCGTGCGCCGTAAGCCATATA
GTGTTGTGTTATTAGATGAAATCGAAAAAGCGCACTCTGATGTACATGAATTATTCTTCCAAGTGTTTGATAAAGGCCAA
ATGGAAGATGGTGAAGGGCGCTTTATCGATTTCAAAAACACTATTTTGCTGTTAACCAGTAATGTGGGCAGCGAGTTACT
GAGTAACTTATTAGCTGATCCAGATACTGCACCGGATCAGGATGGAATATTAACTGCGTTACAACCTGAATTGCTGAAAG
TTTTCCCAGCAGCATTTTTAGGGCGAGTCACGGTTATTCCTTATCTTCCGTTACAGCAAGATGCATTGCAGCACATTGTA
CGGTTACATCTTGACCGGATTGGCGCTCGTTTATACTCGCAGCATCAATTGACACTGAAATACAGTGATGAAGTGGTTGA
CGATGTTGTTAGCCGCTGTGCGGTTTCAGAAACCGGTGCACGTATGCTGATCCGTTACATTGAACAAAATATTACGCCAA
AAATAGGTAAATATATTTTAGGTGATAGTGATGTGAAGCCTGAGCAAATTATTTTCGTTCATAAAAATGAAAATGGATTC
GTGATCGCTTTACAATGA

Protein sequence :
MAITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFAVDVDAFERELAQALAKLPVG
ATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLALLTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEAN
EAASDGSPLYDGALPGEASNAIGAAKSGGTLAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGV
GKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAEKPVILFIDEVHTLIGAGGNA
GTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALTRRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEAL
QAAVRLSHRYIPARQLPDKAISLLDTACARIAVAQHSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSI
AEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLSQVRTSLPLVQTEVNAEVIAS
IVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALMQLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAI
AESMYGGEQNMITINMSEYQESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQ
MEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILTALQPELLKVFPAAFLGRVTVIPYLPLQQDALQHIV
RLHLDRIGARLYSQHQLTLKYSDEVVDDVVSRCAVSETGARMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGF
VIALQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 0.0 59
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-130 46
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-130 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPK_1474 YP_001720220.1 type VI secretion ATPase VFG2076 Protein 0.0 55
YPK_1474 YP_001720220.1 type VI secretion ATPase VFG2084 Protein 1e-138 44