Gene Information

Name : leuS (Daud_1865)
Accession : YP_001717990.1
Strain : Candidatus Desulforudis audaxviator MP104C
Genome accession: NC_010424
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1964296 - 1966776 bp
Length : 2481 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGAAGAGAAGTACGTTTTCGCCGAGATTGAAGAGAAACTGCGCCGCAGGTGGGAAACCGAGGGCATCTATCATGTGCC
GGACTTTTCGAACCGTCCCAAGTACTACTGCCTGGAGATGTTCCCCTACCCTTCGGGAAACTTGCATATGGGACACGTGC
GCAACTACGCCATCGGCGACGTGGTGGCCCGTTTCAAGACGATGCGCGGCTACGACGTTCTGCACCCCATGGGCTGGGAC
GCCTTCGGGCTGCCGGCGGAGAACGCGGCCATTCAACACGGCGTCCCCCCGGCCAGGTGGACCTGGGACAACATCAACGT
CATGCGCACCCAGCTCAAGCTCCTGGGTGTGAGTTACGACTGGCGCCGGGAGCTCGCAACCTGTCACCCGGGGTATTACC
GGTGGACGCAGTGGCTCTTCCTGCAGTTCTACCACCGGGGCCTGGCTTACAAGGCCAAGGCGCCGGTCAACTGGTGCCCT
TCCTGCGCCACAGTGCTGGCCAACGAGCAAGTGGTGGCCGGGGGCTGCGAGCGGTGCAAGACTGCCGTTGAACGGCGCGA
ACTGGAACAGTGGTTCTTCCGGATCACCGCCTACGCCGACCGCCTCCTGAAAGACCTGGCGAAGCTCCCGGGTTGGCCGG
AGAAGGTGAAAGTCATGCAGGAGAACTGGATCGGCCGCAGCACCGGCGCCGAGATCGCCTTCCCGCTGGCGGGGACGGAC
GAGGCGATCCGGGTCTTCACCACCCGCCCGGACACGCTGGGCGGGGTGACCTATATGACCATCGCTCCCGAGCACCCGCT
GGTGTCTAGGGTGACCACCCCCGAGCACCGGGCCGCGGTGGAAGCCTTCACCGAGCGGGCGCGGAGCTTAAGCGAGCTGG
ATCGCACGGCGGGAGAACATGAAAAGGAGGGCCTTTTCACCGGCGCATACTGTGTGAACCCTCTCACCGGGGAGCAGGTG
CCGGTGTTCGTGGCCAACTACGTGCTGATGGAATACGGGACCGGCTGCGTGATGGGTGTCCCGGCCCACGACCAGCGGGA
CTTTGAATTCGCGCGCAAGTACGGACTCCCGGTCCGGGTGGTCATCCAGCCGGAGGGGGATCTTCTGGACGGGGACACCA
TGTCCCAGGCCTACACCGGGCCGGGGCGTCTGGTGAACACTCCGGGCTTTGACCGGATGGCGAACGCGGAGGCGATTCCG
GCTATCACCCGGTACCTGGAGGCCCGCGGCGCGGCCCGGTTTCAGGTGCAGTACCGCCTGCGCGACTGGCTGATTTCCCG
CCAGCGGTACTGGGGGGCGCCGATCCCGATCGTGTACTGTGAGGGGTGCGGCGTGGTGCCGGTGCCCGAGGAAGGGCTCC
CGGTGCTCCTGCCCGAGGACGTGGCTTTCAAGCCGACCGGGCGGTCCCCCCTGACTGAGTCACCGGACTTCGTGAACACC
ACCTGCCCTACGTGCGGCGGGCCGGCCCGGCGGGAAACCGACACCATGGACACCTTTATGTGTTCGTCCTGGTACTACTT
CCGGTTCACCAGTCCCCGGGAGGAAAACGGGCCGTGGGGGTTGGAGCGGGTCGACCGCTGGCTGCCGGTGGACCAGTACA
TCGGCGGGGTGGAGCACGCCATCCTGCACCTGATGTACTCGCGCTTTTTCACCAAGGTACTGTACGATATGGGCCTGGTG
AAGGTCCAGGAACCATTTACCAACTTGCTTACTCAGGGCATGGTCTTGAAGGACGGGGCCAAGATGTCCAAGTCCAAGGG
GAACGTGGTCAGCCCGGAAGACATCCTCAACCGGTACGGGGCCGACACCACCAGGCTGTTCGTTCTTTTCGCCGCCCCGC
CCGAGCGCGACCTGGAGTGGTCCGACCAGGGCGTGGAGGGTTGCTACCGCTTCCTGCAGCGGGTCTGGCGGCTGGTGAAC
TCTGTGGCGGACGAAATCCGGGGGGCGGCGCCCGTGCCGTCGGCCAACCTGGTCGGGGTGAACCGGAGCATGCGCCGGCT
GACCCACCAGACCATCAAGAAAGTGACCGAGGACATCGAAACCCGCTTCAACTTCAACACGGCTATCAGCGCGGCGATGG
AGTTGGTCAACGGGATGTACCACTTCCGCGACCGGGTGGCGCCGGTAAACCGGGACCCGGCCGTCATGCGGGAGGCGGTG
GAGCGACTGTTGCTCCTGCTGGCGCCGTTTGCCCCGTTCCTGGCCGACGAGCTGTGGGCGCGCACGGGGCATCCGGAGAG
CATCCACCGGGAGCCCTGGCCGGAATACGACCCTGAGCTTCTGGTCGAGGACCAGGTGGAGATCGTGGTTCAGATCAACG
GGCGGGTGCGCGACCGCCTGATGGTCGCGGCCGACATCGCCCCGGAAGCGATGCGGGACACTGTGCTGGAACAGCCCCGG
GTTCAGGCGCTGGTAGCGGGGAAAGAGATCGTCAAGGTCGTGCCGGTGCCCGGCAAACTCGTCAACATTGTCGTCCGTTA
A

Protein sequence :
MEEKYVFAEIEEKLRRRWETEGIYHVPDFSNRPKYYCLEMFPYPSGNLHMGHVRNYAIGDVVARFKTMRGYDVLHPMGWD
AFGLPAENAAIQHGVPPARWTWDNINVMRTQLKLLGVSYDWRRELATCHPGYYRWTQWLFLQFYHRGLAYKAKAPVNWCP
SCATVLANEQVVAGGCERCKTAVERRELEQWFFRITAYADRLLKDLAKLPGWPEKVKVMQENWIGRSTGAEIAFPLAGTD
EAIRVFTTRPDTLGGVTYMTIAPEHPLVSRVTTPEHRAAVEAFTERARSLSELDRTAGEHEKEGLFTGAYCVNPLTGEQV
PVFVANYVLMEYGTGCVMGVPAHDQRDFEFARKYGLPVRVVIQPEGDLLDGDTMSQAYTGPGRLVNTPGFDRMANAEAIP
AITRYLEARGAARFQVQYRLRDWLISRQRYWGAPIPIVYCEGCGVVPVPEEGLPVLLPEDVAFKPTGRSPLTESPDFVNT
TCPTCGGPARRETDTMDTFMCSSWYYFRFTSPREENGPWGLERVDRWLPVDQYIGGVEHAILHLMYSRFFTKVLYDMGLV
KVQEPFTNLLTQGMVLKDGAKMSKSKGNVVSPEDILNRYGADTTRLFVLFAAPPERDLEWSDQGVEGCYRFLQRVWRLVN
SVADEIRGAAPVPSANLVGVNRSMRRLTHQTIKKVTEDIETRFNFNTAISAAMELVNGMYHFRDRVAPVNRDPAVMREAV
ERLLLLLAPFAPFLADELWARTGHPESIHREPWPEYDPELLVEDQVEIVVQINGRVRDRLMVAADIAPEAMRDTVLEQPR
VQALVAGKEIVKVVPVPGKLVNIVVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 9e-159 44