Gene Information

Name : guaA (Daud_1635)
Accession : YP_001717769.1
Strain : Candidatus Desulforudis audaxviator MP104C
Genome accession: NC_010424
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1724814 - 1726355 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGCAGGCACCCGTTGATGAGTTTGTGCTGGTGCTCGATTTCGGCGGGCAGTACACCCAGCTGATCGCCCGGCGGATCAG
AGAGTGCCGGGTTTATTGCGAAATCCTGCCCTACCACACTCCCGCGGAGGACATCGTCTCCCGGCGGCCGAAGGGGATTG
TCTTTTCCGGCGGCCCGTCGAGCGTCTACCAGGAGGGCGCGCCCCAGTGCGCGGTTTCGCTTTACGACGCCGGGATTCCG
ATCCTGGGGATCTGCTACGGCATGCAGCTGATGGCCCGCCAGCTTGGCGGCACGGTCTCACCGGCGGAGCGGCGGGAATA
CGGCAAGACCGAGCTAGAGGTGTTGGACGGGAGCGGTTTGTTCCGGGGACTGGAGGACCGTGAAAGGTGCTGGATGAGCC
ACGGCGACCGGGTGGACGCGCCGCCCCCGGGTTTCGCGGTTACGGCGCGCACCGCCCACTCGCCCGTCGCGGCGATGGCC
GACCCGGTGCGGAAGTTGTTCGGGTTGCAGTTTCACCCCGAGGTGCGGCATACCCCCAGGGGTGTTCAGATTCTGCAGCG
TTTTCTTTACGAGGTGTGCGGCTGCCGCGGAGACTGGACCATGTCTTCGTTCCTGGAGGACGCGGTCGCCCAGATTCGGC
GGGAGGTCGGTGACGGCCGGGTGTTGTGCGCCCTGAGCGGGGGTGTGGACTCTTCGGTGGCGGCGGCGCTGGTGCACCGG
GCCGTGGGAGACCGGCTGACCTGCGTGTTTGTCGATCACGGCCTGCTGCGGCAGGGTGAGTCCGAACAGGTACGGGAGAC
CTTCGCGCGCCGCTTCGGGATGCGGCTGGTGCACGTGGAAGCCCAGGACCGCTTTTTGGACCGCCTGGCCGGGGTGGAAG
ACCCGGAGGCTAAACGGCGGATCATCGGGACGGAGTTCATCCGGGTCTTTGAGGAGGAAGCGGCCAAGCTCGGCCCGATC
GACTTCCTGGTCCAGGGGACCATCTACCCGGACGTGGTGGAGAGCGGAACGGCCACCGGGGCGGTGATCAAGACCCACCA
CAACGTCGGGGGGCTTCCCGAAGACATCCGTTTTAAGCTGATTGAACCGCTGCGTTGGCTTTTCAAGGATGAGGTGCGCG
TGCTCGGTGAGGAGTTGGGCCTGCCGGAAGAGATCGTGTGGCGGCAGCCTTTCCCGGGGCCGGGGCTGGCGGTGCGCGTG
CTGGGCGAGGTCACCCGGGAGAAACTGGAGTGCTTGCGCGCGGCCGACGCGGTCGTGGACGAGGAGATCCGGCGGGCCGG
GCTGTACCGGCAGGTCTGGCAGTCCTTCGCCGTGCTGCCTCCTATTCGGAGCGTGGGTGTGATGGGGGATGAGCGGACTT
ACGGCTATACTATTGTGATCCGGGCGGTGGAAAGCGTGGACGCCATGACCGCCGACTGGGTGCGGCTGCCGTACGAGGTG
CTGGAGACGATGTCACGGCGGCTGGTCAACGAGGTGAAAGGCATCAACCGGGTGGTGTACGACATTACGTCCAAGCCACC
GGGAACCATAGAGTGGGAGTAA

Protein sequence :
MQAPVDEFVLVLDFGGQYTQLIARRIRECRVYCEILPYHTPAEDIVSRRPKGIVFSGGPSSVYQEGAPQCAVSLYDAGIP
ILGICYGMQLMARQLGGTVSPAERREYGKTELEVLDGSGLFRGLEDRERCWMSHGDRVDAPPPGFAVTARTAHSPVAAMA
DPVRKLFGLQFHPEVRHTPRGVQILQRFLYEVCGCRGDWTMSSFLEDAVAQIRREVGDGRVLCALSGGVDSSVAAALVHR
AVGDRLTCVFVDHGLLRQGESEQVRETFARRFGMRLVHVEAQDRFLDRLAGVEDPEAKRRIIGTEFIRVFEEEAAKLGPI
DFLVQGTIYPDVVESGTATGAVIKTHHNVGGLPEDIRFKLIEPLRWLFKDEVRVLGEELGLPEEIVWRQPFPGPGLAVRV
LGEVTREKLECLRAADAVVDEEIRRAGLYRQVWQSFAVLPPIRSVGVMGDERTYGYTIVIRAVESVDAMTADWVRLPYEV
LETMSRRLVNEVKGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-151 58
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-152 58
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-151 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-144 57