Gene Information

Name : hemC (Daud_1347)
Accession : YP_001717488.1
Strain : Candidatus Desulforudis audaxviator MP104C
Genome accession: NC_010424
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1422500 - 1423429 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGGCGGGAGGTTGTGGTCGGCACGCGCGGGTCCCGGCTGGCCCTGGCGCAGGCCGACTGGGTCATCGACCACCTGCG
GGCGCGCTACCCTCGGGTGAGCTTCGTGCGCAAGGAAATCCGGACCACCGGAGATAATATCCTGGAAGTGGCCCTGGCCA
AGATCGGCGACAAGGGCCTTTTTACCAAGGAACTCGAGCAGGCGCTGCTCCACCGGGAAATCGACCTGGCGGTGCACAGC
ATGAAGGATCTGCCCACCGGGCTGCCCGAGGGTCTGGTCATCGGGGCGGTTTCCGTCCGGGAGTACCCGGGCGACGTGTT
CATTTCCCGCGGGGGGGAGCGGCTGGAGGAGCTGCCGGCAGGCGCGGTGCTCGGGACCAGCAGCCTGCGGCGCACGGCCC
AGCTCCTGGCCTACCGGCCCGACCTGCAAGTGATCCCGGTACGGGGCAACGTCCAGACCCGGCTCCGGAAACTGGACGAG
GGCGTGGTGGACGCCCTGGTGCTGGCCTGGGCCGGGCTGTTCCGGTTGGGCCTTACCGAGAGGGTCACCCACCGCATACC
GGTGGCCATGTGCCTGCCGGCGGTCGGTCAGGGGGCGCTGGGGATCGAGGCGCGTGCGGACGACGCTGAGATCCTCGAAA
TGCTGCGAACGATTGACCACGCGCCGACCCGCGCGGCCGTGCAGGCCGAGAGGACGCTGTTGCGGCGCCTGGAAGGCGGC
TGCCAGGTACCGGTCGGGGCCCTGGGACGGTTCCGGGACGGGCGCCTGGTATTGGAGGCGGTGGTGGCCTCCCTGGACGG
GACGGAATTGGTGCGGGCCCAAGAGTCCGGTCCGGCGGACCGGCCGGAGGCTCTCGGCAACAGTCTGGCCGTCCGGCTGC
TGGAGATGGGCGCCGGCGAGATTCTGGCCCGGGTGCGTGCGGGTGCGTAA

Protein sequence :
MRREVVVGTRGSRLALAQADWVIDHLRARYPRVSFVRKEIRTTGDNILEVALAKIGDKGLFTKELEQALLHREIDLAVHS
MKDLPTGLPEGLVIGAVSVREYPGDVFISRGGERLEELPAGAVLGTSSLRRTAQLLAYRPDLQVIPVRGNVQTRLRKLDE
GVVDALVLAWAGLFRLGLTERVTHRIPVAMCLPAVGQGALGIEARADDAEILEMLRTIDHAPTRAAVQAERTLLRRLEGG
CQVPVGALGRFRDGRLVLEAVVASLDGTELVRAQESGPADRPEALGNSLAVRLLEMGAGEILARVRAGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-61 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-61 50