Gene Information

Name : dhfrI (ABAYE3644)
Accession : YP_001715373.1
Strain : Acinetobacter baumannii AYE
Genome accession: NC_010410
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase type 1 (dihydrofolate reductase type I) (trimethoprim resistance protein)
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 3676916 - 3677389 bp
Length : 474 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme

DNA sequence : 
GTGAAACTATCACTAATGGTAGCTATATCGAAGAATGGAGTTATCGGGAATGGCCCTGATATTCCATGGAGTGCCAAAGG
TGAACAGCTCCTGTTTAAAGCTATTACCTATAACCAATGGCTGTTGGTTGGACGCAAGACTTTTGAATCAATGGGAGCAT
TACCCAACCGAAAGTATGCGGTCGTAACACGTTCAAGTTTTACATCTGACAATGAGAACGTATTGATCTTTCCATCAATT
AAAGATGCTTTAACCAACCTAAAGAAAATAACGGATCATGTCATTGTTTCAGGTGGTGGGGAGATATACAAAAGCCTGAT
CGATCAAGTAGATACACTACATATATCTACAATAGACATCGAGCCGGAAGGTGATGTTTACTTTCCTGAAATCCCCAGCA
ATTTTAGGCCAGTTTTTACCCAAGACTTCGCCTCTAACATAAATTATAGTTACCAAATCTGGCAAAAGGGTTAA

Protein sequence : 
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSI
KDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA1 AGF34987.1 DfrA1 dihydrofolate reductase Not tested SGI1 Protein 2e-69 100
dfrA1 AAX48777.1 DfrA1 trimethoprim-insensitive dihydrofolate reductase Not tested SGI2 Protein 2e-69 100
dfrI CAJ77029.1 dihydrofolate reductase type I Not tested AbaR1 Protein 2e-69 100
dfrA15 AGK07099.1 DfrA15 dihydrofolate reductase Not tested SGI1 Protein 3e-66 92
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 2e-55 76
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 2e-55 76
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 2e-53 75
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 2e-53 75