Gene Information

Name : veb-1 (ABAYE3623)
Accession : YP_001715362.1
Strain : Acinetobacter baumannii AYE
Genome accession: NC_010410
Putative virulence/resistance : Resistance
Product : beta-lactamase VEB-1
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : 3.5.2.6
Position : 3660737 - 3661636 bp
Length : 900 bp
Strand : -
Note : Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10049269; Product type e : enzyme

DNA sequence :
ATGAAAATCGTAAAAAGGATATTATTAGTATTGTTAAGTTTATTTTTTACAATTGTGTATTCAAATGCTCAAACTGACAA
CTTAACTTTGAAAATTGAGAATGTTTTAAAGGCAAAAAATGCCAGAATAGGAGTAGCAATATTCAACAGCAATGAGAAGG
ATACTTTGAAGATTAATAACGACTTCCATTTCCCGATGCAAAGCGTTATGAAATTTCCGATTGCTTTAGCCGTTTTGTCT
GAGATAGATAAAGGGAATCTTTCTTTTGAACAAAAAATAGAGATTACCCCTCAAGACCTTTTGCCTAAAACGTGGAGTCC
GATTAAAGAGGAATTCCCTAATGGAACAACTTTGACGATTGAACAAATACTAAATTATACAGTATCAGAGAGCGACAATA
TTGGTTGTGATATTTTGCTAAAATTAATCGGAGGAACTGATTCTGTTCAAAAATTCTTGAATGCTAATCATTTCACTGAT
ATTTCAATCAAAGCAAACGAAGAACAAATGCACAAGGATTGGAATACCCAATATCAAAATTGGGCAACCCCAACAGCGAT
GAACAAACTGTTAATAGATACTTATAATAATAAGAACCAATTACTTTCTAAAAAAAGTTATGATTTTATTTGGAAAATTA
TGAGAGAAACAACAACAGGAAGTAACCGATTAAAAGGACAATTACCAAAGAATACAATTGTTGCTCATAAAACAGGGACT
TCCGGAATAAATAATGGAATTGCAGCAGCCACTAATGATGTTGGGGTAATTACTTTACCGAATGGACAATTAATTTTTAT
AAGCGTATTTGTTGCAGAGTCCAAAGAAACTTCGGAAATTAATGAAAAGATTATTTCAGACATTGCAAAAATAACGTGGA
ATTACTATTTGAATAAATAA

Protein sequence :
MKIVKRILLVLLSLFFTIVYSNAQTDNLTLKIENVLKAKNARIGVAIFNSNEKDTLKINNDFHFPMQSVMKFPIALAVLS
EIDKGNLSFEQKIEITPQDLLPKTWSPIKEEFPNGTTLTIEQILNYTVSESDNIGCDILLKLIGGTDSVQKFLNANHFTD
ISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNKNQLLSKKSYDFIWKIMRETTTGSNRLKGQLPKNTIVAHKTGT
SGINNGIAAATNDVGVITLPNGQLIFISVFVAESKETSEINEKIISDIAKITWNYYLNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
bla VEB-1 CAJ77043.1 Betalactamase Not tested AbaR1 Protein 4e-135 100
ABK1_0262 YP_005512834.1 Extended-spectrum beta-lactamase PER-1 precursor Not tested AbaR4d Protein 2e-50 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
veb-1 YP_001715362.1 beta-lactamase VEB-1 NC_010410.6002875.p0 Protein 2e-135 100
veb-1 YP_001715362.1 beta-lactamase VEB-1 AF010416.1.gene1.p01 Protein 2e-135 100
veb-1 YP_001715362.1 beta-lactamase VEB-1 AY536519.1.gene1.p01 Protein 1e-134 99
veb-1 YP_001715362.1 beta-lactamase VEB-1 AY027870.1.gene1.p01 Protein 3e-135 99
veb-1 YP_001715362.1 beta-lactamase VEB-1 EF420108.1.gene1.p01 Protein 4e-134 99
veb-1 YP_001715362.1 beta-lactamase VEB-1 EF136375.1.gene1.p01 Protein 8e-135 99
veb-1 YP_001715362.1 beta-lactamase VEB-1 GQ396303.1.gene1.p01 Protein 4e-48 42
veb-1 YP_001715362.1 beta-lactamase VEB-1 X93314.gene.p01 Protein 5e-48 42
veb-1 YP_001715362.1 beta-lactamase VEB-1 FJ627180.1.gene1.p01 Protein 1e-51 41
veb-1 YP_001715362.1 beta-lactamase VEB-1 AY740681.1.gene9.p01 Protein 5e-51 41