Gene Information

Name : aadB (ABAYE3622)
Accession : YP_001715361.1
Strain : Acinetobacter baumannii AYE
Genome accession: NC_010410
Putative virulence/resistance : Resistance
Product : 2''-aminoglycoside nucleotidyltransferase AadB
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.46
Position : 3660059 - 3660592 bp
Length : 534 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12904353; Product type e : enzyme

DNA sequence :
ATGGACACAACGCAGGTCACATTGATACACAAAATTCTAGCTGCGGCAGATGAGCGAAATCTGCCGCTCTGGATCGGTGG
GGGCTGGGCGATCGATGCACGGCTAGGGCGTGTAACACGCAAGCACGATGATATTGATCTGACGTTTCCCGGCGAGAGGC
GCGGCGAGCTCGAGGCAATAGTTGAAATGCTCGGCGGGCGCGTCATGGAGGAGTTGGACTATGGATTCTTAGCGGAGATC
GGGGATGAGTTACTTGACTGCGAACCTGCTTGGTGGGCAGACGAAGCGTATGAAATCGCGGAGGCTCCGCAGGGCTCGTG
CCCAGAGGCGGCTGAGGGCGTCATCGCCGGGCGGCCAGTCCGTTGTAACAGCTGGGAGGCGATCATCTGGGATTACTTTT
ACTATGCCGATGAAGTACCACCAGTGGACTGGCCTACAAAGCACATAGAGTCCTACAGGCTCGCATGCACCTCACTCGGG
GCGGAAAAGGTTGAGGTCTTGCGTGCCGCTTTCAGGTCGCGATATGCGGCCTAA

Protein sequence :
MDTTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEI
GDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLG
AEKVEVLRAAFRSRYAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadB CAJ77044.1 Aminoglycoside adenylyltransferase Not tested AbaR1 Protein 3e-78 100
aadB YP_005176240.1 aminoglycoside 2''-O-adenyltransferase protein Not tested ICEPmu1 Protein 2e-79 100
aadB AET25384.1 aminoglycoside-2-O-adenyltransferase Not tested PAGI-2(C) Protein 1e-75 98
aadB AFG30107.1 aminoglycoside-2-0-adenyltransferase Not tested PAGI-2 Protein 1e-75 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadB YP_001715361.1 2''-aminoglycoside nucleotidyltransferase AadB AY204504.gene.p01 Protein 1e-78 100
aadB YP_001715361.1 2''-aminoglycoside nucleotidyltransferase AadB JF800667.1.gene1.p01 Protein 1e-78 100
aadB YP_001715361.1 2''-aminoglycoside nucleotidyltransferase AadB NC_010410.6002958.p0 Protein 1e-78 100
aadB YP_001715361.1 2''-aminoglycoside nucleotidyltransferase AadB U37105.2.gene3.p01 Protein 1e-78 100
aadB YP_001715361.1 2''-aminoglycoside nucleotidyltransferase AadB DQ522237.1.gene2.p01 Protein 1e-78 100
aadB YP_001715361.1 2''-aminoglycoside nucleotidyltransferase AadB AJ704863.gene26.p01 Protein 1e-78 100