Gene Information

Name : hemC (ABAYE3508)
Accession : YP_001715265.1
Strain : Acinetobacter baumannii AYE
Genome accession: NC_010410
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3564797 - 3565741 bp
Length : 945 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGTTTGACCAGCCCATGCTTGAATTTATGAAAACCTTGAAAATTGCTACACGACAAAGCCCACTTGCTCTTTGGCAGGC
AGAACATATTCGCGCCCGTTTACAGGAGCGTCACCCAGATTTAACGGTGGAGTTGGTTAAGTTTGTCACGCAGGGCGATA
AAATTTTAGATACACCTTTAGCAAAAATTGGTGGTAAAGGGTTGTTCGTTAAAGAATTGGAAGCAGCACTTTTAGATGGT
CGTGCGGACCTTGCTGTACATTCAATGAAAGATGTTCCGATGGCATTACCAGAAGGTTTAACTTTGGCCGTAATTTGCGA
ACGTGAAGATCCGTTAGATGCTTTTGTTTCGAATCAATTTGAAAAATTTGCTGATTTGCCGCAAGGAGCAAAAGTTGGCA
CCTCAAGTTTACGTCGTAAATCACAAATTTTAAAACAACGTCCAGATCTACAAATTATTGATTTACGTGGTAATGTCGGT
ACCCGCTTAGCGAAGCTAGACGATGGTCAATATGATGCCATTATCTTGGCGAGTGCTGGTTTAAAACGTTTAGGATTGGC
AGAACGCATTCGCCACTGTATCGAGCCAAGTGTAAGTTTGCCTGCGGTTGGTCAGGGCGCTCTTGGTTTGGAATGCCGTG
CAGATGATCAAGAAGTGTTGGCTTTAATTCAGCCACTTCTACACCCAGAGACAGATGTATGTGTACGTGCTGAGCGAGCA
TTCAATGCTTATCTTGAAGGTGGTTGTCAGGTGCCGATTGCAGGTTATGCAACACTCCAAGATGGTAAAATTCATATTGA
AGGCCGTGTAGGTAGTGTTGATGGGCAAACATTATTACGGGCTGAGCTTACAGATGAAGCGAATAATGCTCAGCAATTAG
GTGAAAACCTTGCTCGGAACTTACTTGATCAAGGCGCTGGTGATTTATTAAAGGCCCTCTACTAA

Protein sequence :
MFDQPMLEFMKTLKIATRQSPLALWQAEHIRARLQERHPDLTVELVKFVTQGDKILDTPLAKIGGKGLFVKELEAALLDG
RADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFADLPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVG
TRLAKLDDGQYDAIILASAGLKRLGLAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLALIQPLLHPETDVCVRAERA
FNAYLEGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQGAGDLLKALY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-144 99
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-144 99