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Name : bla-OXA-69 (ABAYE2122) Accession : YP_001713983.1 Strain : Acinetobacter baumannii AYE Genome accession: NC_010410 Putative virulence/resistance : Resistance Product : carbapenem-hydrolyzing oxacillinase Function : - COG functional category : V : Defense mechanisms COG ID : COG2602 EC number : 3.5.2.6 Position : 2175317 - 2176141 bp Length : 825 bp Strand : + Note : Evidence 1a : Function experimentally demonstrated in the studied strain; Product type e : enzyme DNA sequence : ATGAACATTAAAGCACTCTTACTTATAACAAGCGCTATTTTTATTTCAGCCTGCTCACCTTATATAGTGACTGCTAATCC AAATCACAGTGCTTCAAAATCTGATGACAAAGCAGAGAAAATTAAAAATTTATTTAACGAAGCACACACTACGGGTGTTT TAGTTATCCATCAAGGTCAAACTCAACAAAGCTATGGTAATGATCTTGCTCGTGCTTCGACCGAGTATGTACCTGCTTCG ACCTTCAAAATGCTTAATGCTTTGATCGGCCTTGAGCACCATAAGGCAACCACCACAGAAGTATTTAAATGGGATGGGGA AAAAAGGCTATTCCCAGAATGGGAAAAGAACATGACCCTAGGCGATGCTATGAAAGCTTCCGCTATTCCGGTTTATCAAG ATTTAGCTCGTCGTATTGGACTTGAGCTCATGTCTAAGGAAGTGAAGCGTGTTGGTTATGGCAATGCAGATATCGGTACC CAAGTCGATAATTTTTGGCTGGTGGGTCCTCTAAAAATTACTCCTCAGCAAGAGGCACAGTTTGCTTACAAGCTAGCTAA TAAAACGCTTCCATTTAGCCAAAAAGTCCAAGATGAAGTGCAATCCATGCTATTCATAGAAGAAAAGAATGGAAATAAAA TATACGCAAAAAGTGGTTGGGGATGGGATGTAAACCCACAAGTAGGCTGGTTAACTGGATGGGTTGTTCAGCCTCAAGGG AATATTGTAGCGTTCTCCCTTAACTTAGAAATGAAAAAAGGAATACCTAGCTCTGTTCGAAAAGAGATTACTTATAAAAG TTTAGAACAATTAGGTATTTTATAG Protein sequence : MNIKALLLITSAIFISACSPYIVTANPNHSASKSDDKAEKIKNLFNEAHTTGVLVIHQGQTQQSYGNDLARASTEYVPAS TFKMLNALIGLEHHKATTTEVFKWDGEKRLFPEWEKNMTLGDAMKASAIPVYQDLARRIGLELMSKEVKRVGYGNADIGT QVDNFWLVGPLKITPQQEAQFAYKLANKTLPFSQKVQDEVQSMLFIEEKNGNKIYAKSGWGWDVNPQVGWLTGWVVQPQG NIVAFSLNLEMKKGIPSSVRKEITYKSLEQLGIL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| oxa-Ab | ACV89830.1 | carbapenem-hydrolyzing oxacillinase OXA-69 | Not tested | AbaR6 | Protein | 4e-126 | 100 |
| oxa-Ab | ACV89832.1 | carbapenem-hydrolyzing oxacillinase OXA-69 | Not tested | AbaR7 | Protein | 4e-126 | 100 |
| oxa-Ab | ADK35783.1 | carbapenem-hydrolyzing oxacillinase OXA-69 | Not tested | AbaR8 | Protein | 4e-126 | 100 |
| oxa-23 | AFV47996.1 | class D beta-lactamase OXA-23 | Not tested | delta-AbaR25 | Protein | 2e-80 | 58 |
| oxa23 | AEZ06035.1 | OXA-23 class D beta-lactamase | Not tested | Tn6167 | Protein | 6e-80 | 58 |
| BJAB0715_00989 | YP_008216137.1 | Beta-lactamase class D | Not tested | AbaR27 | Protein | 2e-80 | 58 |
| oxa23 | AEO37447.1 | class D beta-lactamase OXA-23 | Not tested | AbaR4 | Protein | 2e-80 | 58 |
| oxa-23 | AFV47968.1 | class D beta-lactamase OXA-23 | Not tested | AbaR25 | Protein | 2e-80 | 58 |
| bla(Oxa-23) | AFH57213.1 | carbapenemase | Not tested | AbaR4b | Protein | 2e-80 | 58 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | NC_011595.7059224.p0 | Protein | 3e-126 | 100 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750911.1.gene1.p01 | Protein | 3e-126 | 100 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ392963.1.gene1.p01 | Protein | 7e-125 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AM279652.1.gene1.p01 | Protein | 3e-125 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU019534.1.gene1.p01 | Protein | 4e-123 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ734813.1.gene1.p01 | Protein | 2e-124 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650036.1.gene1.p01 | Protein | 6e-126 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650038.1.gene1.p01 | Protein | 4e-126 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AB634250.1.gene1.p01 | Protein | 3e-124 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650035.1.gene1.p01 | Protein | 5e-124 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ309277.1.gene1.p01 | Protein | 3e-124 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU019535.1.gene1.p01 | Protein | 1e-123 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750908.1.gene1.p01 | Protein | 3e-125 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU019536.1.gene1.p01 | Protein | 3e-124 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ335566.1.gene1.p01 | Protein | 2e-125 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750909.1.gene1.p01 | Protein | 1e-124 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF581285.1.gene1.p01 | Protein | 5e-125 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650033.1.gene1.p01 | Protein | 6e-126 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU220744.1.gene1.p01 | Protein | 1e-119 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AM231719.1.gene1.p01 | Protein | 3e-125 | 99 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU547446.1.gene1.p1 | Protein | 5e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113559.1.gene1.p01 | Protein | 1e-122 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AJ309734.2.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | FJ872530.1.gene1.p01 | Protein | 3e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ425492.1.gene1.p01 | Protein | 1e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF653400.1.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113562.1.gene1.p01 | Protein | 4e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750913.1.gene1.p01 | Protein | 6e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650032.1.gene1.p01 | Protein | 9e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | JN248564.1.gene1.p01 | Protein | 9e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM570035.1.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU029998.1.gene2.p01 | Protein | 3e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU547445.1.gene1.p1 | Protein | 4e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750910.1.gene1.p01 | Protein | 9e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113563.1.gene1.p01 | Protein | 7e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU220745.1.gene1.p01 | Protein | 4e-119 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ519089.1.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113558.1.gene1.p01 | Protein | 2e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ519086.1.gene2.p01 | Protein | 3e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750907.1.gene1.p01 | Protein | 7e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY862132.1.gene1.p01 | Protein | 2e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ425493.1.gene1.p01 | Protein | 2e-122 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ385606.gene.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU375515.1.gene1.p1 | Protein | 4e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ425494.1.gene1.p01 | Protein | 4e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ519087.1.gene1.p01 | Protein | 6e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650034.1.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ734812.1.gene1.p01 | Protein | 1e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ734811.1.gene1.p01 | Protein | 3e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | GQ853681.1.gene1.p1 | Protein | 9e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ309276.1.gene1.p01 | Protein | 7e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ519088.1.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | GQ853680.1.gene1.p1 | Protein | 3e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113564.1.gene1.p01 | Protein | 2e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM570036.1.gene1.p01 | Protein | 4e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | JN603240.1.gene1.p1 | Protein | 7e-125 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY750912.1.gene1.p01 | Protein | 2e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113560.1.gene1.p01 | Protein | 6e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ998857.1.gene1.p01 | Protein | 1e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM113561.1.gene1.p01 | Protein | 3e-124 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ425495.1.gene1.p01 | Protein | 2e-123 | 98 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EU547447.1.gene1.p1 | Protein | 2e-124 | 97 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | GQ853679.1.gene1.p1 | Protein | 3e-124 | 97 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | JN215211.1.gene1.p01 | Protein | 2e-124 | 97 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ491200.1.gene1.p01 | Protein | 2e-124 | 97 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ888718.1.gene1.p01 | Protein | 4e-124 | 97 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF650037.1.gene1.p01 | Protein | 2e-124 | 97 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | NC_012813.7996741.p0 | Protein | 2e-82 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | NC_013506.8571544.p0 | Protein | 2e-82 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AF201827.1.gene1.p01 | Protein | 2e-82 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AJ239129.2.gene1.p01 | Protein | 2e-82 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | NC_013277.8458023.p0 | Protein | 2e-82 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF534256.2.gene1.p01 | Protein | 7e-83 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AF509241.1.gene1.p01 | Protein | 2e-82 | 65 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AM991978.1.gene1.p01 | Protein | 5e-82 | 64 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AF201826.1.gene1.p01 | Protein | 4e-82 | 64 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HQ122933.1.gene1.p01 | Protein | 8e-79 | 59 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488990.1.gene1.p1 | Protein | 9e-81 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488987.1.gene1.p1 | Protein | 3e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488986.1.gene1.p1 | Protein | 8e-81 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488992.1.gene1.p1 | Protein | 2e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY762325.1.gene1.p01 | Protein | 1e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY795964.gene.p01 | Protein | 9e-81 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | JN638887.1.gene1.p01 | Protein | 3e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | NC_011586.7044972.p0 | Protein | 9e-81 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488991.1.gene1.p1 | Protein | 3e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488988.1.gene1.p1 | Protein | 6e-81 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | HM488989.1.gene1.p1 | Protein | 1e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AF201828.gene.p01 | Protein | 1e-80 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | FJ194494.1.gene1.p01 | Protein | 2e-79 | 58 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY288523.1.gene1.p01 | Protein | 5e-79 | 57 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | GU831575.1.gene1.p01 | Protein | 1e-70 | 49 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | EF102240.1.gene13.p0 | Protein | 3e-71 | 49 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | NC_010481.6155789.p0 | Protein | 2e-71 | 49 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | DQ519090.1.gene1.p01 | Protein | 3e-71 | 49 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY665723.gene.p01 | Protein | 2e-71 | 49 |
| bla-OXA-69 | YP_001713983.1 | carbapenem-hydrolyzing oxacillinase | AY306130.1.gene1.p01 | Protein | 1e-44 | 43 |
