Gene Information

Name : ABSDF0066 (ABSDF0066)
Accession : YP_001705819.1
Strain : Acinetobacter baumannii SDF
Genome accession: NC_010400
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.132
Position : 66730 - 68004 bp
Length : 1275 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme

DNA sequence :
ATGCAAATTGCCAAATTAAAAATAGCAATTATTGGGTTAGGCTATGTTGGCTTGCCGTTGGCAGTTGAGTTTGGGAAAAA
GGTACCGGTTGTCGGCTTTGATATTTATCAAAAACGTATAGATGAGCTTAAGAATGGTCAAGATCATACCTTAGAAGTTT
CACCTGAAGAATTAAAGCAAGCTGTTCACCTCAAATATACTGCTCATTTAGATGATTTACAGGATTCTAATTTTTTCATA
GTCACAGTACCTACACCAATTGATGACTTTAAGCAGCCTGATTTAACCCCTTTAATTAAAGCCTCGACGAGTATTGGGCA
GGTTTTAAAAAAAGGTGATGTAGTGGTATATGAGTCCACCGTATATCCAGGTGCAACAGAAGAAGTATGTATTCCTGTTT
TGGAAAAAATATCTGGACTCAAGTTTAATCAAGATTTCTTTGCAGGTTATAGCCCTGAGCGGATTAACCCCGGTGATAAG
CAGCACCGCGTAACTAATATTTTAAAAATTACATCGGGTTCCACACCTGAGGTAGCTGATTATATTGATGAAGTTTATAA
TTTAATTATTGAGGCGGGCACTCATAAGGCGCCGAATATAAAAGTAGCAGAAGCAGCTAAAGTAATTGAAAACACTCAGC
GCGATGTCAATATCGCTCTGATTAATGAATTGGCACTTATTTTTAATAAATTAGATATTGATACCGAAGATGTACTTAAG
GCTGCTGGTACGAAATGGAACTTTTTACCATTCCGACCTGGATTGGTGGGGGGGCATTGTATAGGTGTAGATCCCTATTA
CCTTACACATAAAGCCCAGTCTATCGGGCTGCATCCCGAAATTATTTTAGCAGCTCGGCGCTTAAATGATCGTATGGGTG
AGCATGTAGCAACTCAGCTCATTAAAGAGATGGTTAAACAGCGTATTCAGGTGGTTGGTGCTCGTATTTTAGTAATGGGC
CTTAGTTTTAAAGAAAATTGCCCTGATATTCGTAATACAAAAATTGTCGATTTTATTAAAGCGTTGAAAGAATACGATTT
AGATTTAGATATCTATGACCCATGGGTAGATGATACAGAAGTACAACACGAATATGGTTTAGCGCCAATTAAAGAATTGC
AACAAGGCTTGTATGATGCGATCGTCATTGCGGTAGCACATAATCAGTTTAAGTCCATGAGTGTGGAAGAATTTCATGCT
TTAGGTAAAGAGAAGCATGTTCTTTATGATTTGAAATATGTTTTGGATAAAGAAAGTTCAAATATTAGACTTTGA

Protein sequence :
MQIAKLKIAIIGLGYVGLPLAVEFGKKVPVVGFDIYQKRIDELKNGQDHTLEVSPEELKQAVHLKYTAHLDDLQDSNFFI
VTVPTPIDDFKQPDLTPLIKASTSIGQVLKKGDVVVYESTVYPGATEEVCIPVLEKISGLKFNQDFFAGYSPERINPGDK
QHRVTNILKITSGSTPEVADYIDEVYNLIIEAGTHKAPNIKVAEAAKVIENTQRDVNIALINELALIFNKLDIDTEDVLK
AAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSIGLHPEIILAARRLNDRMGEHVATQLIKEMVKQRIQVVGARILVMG
LSFKENCPDIRNTKIVDFIKALKEYDLDLDIYDPWVDDTEVQHEYGLAPIKELQQGLYDAIVIAVAHNQFKSMSVEEFHA
LGKEKHVLYDLKYVLDKESSNIRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-142 67
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-142 67
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-112 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ABSDF0066 YP_001705819.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 6e-143 67