Gene Information

Name : thyA (ABSDF3052)
Accession : YP_001708181.1
Strain : Acinetobacter baumannii SDF
Genome accession: NC_010400
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2810982 - 2811824 bp
Length : 843 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGTGCATATTTAGACCTTCTACAACATATCCTTGATAATGGCGGTGACAAAGGCGACCGTACAGGCACAGGAACCCG
TTCTGTATTTGGTCATCAAATGCGTTTTGATCTCTCTAAGGGTTTTCCTTTACTCACCACAAAAAAAGTTCACTTTCGTT
CTATCGTGATTGAGTTACTTTGGTTCTTAAAAGGCGATACTAACGTTAAGTACTTACAAGACAATAAAGTCACCATTTGG
GATGAATGGGCAACAGCAGAACAAACTGCCCGTTTCGGCCGCCCAGAACATGAGCTTGGCCCAGTTTATGGCCATCAATG
GCGTAATTTCGGCGCAACTAAAAATGCCGATGGTACTTATAACCAAGATGGTTTTGACCAAATTAAATGGTTAATTAATG
AAATTAAAACCAACCCAAATTCACGCCGTTTAATTGTCTCTGGCTGGAACCCAAATGAGGCTGGACAAGTTGCTTTACCG
CCTTGCCATACGCTCTTCCAATTCTTCGTACAAGACAACAAGTTGTCATGCCAGCTTTATCAACGTAGTGCTGACGTATT
CTTAGGCGTGCCATTTAATATTGCCAGCTATGCCCTACTCACCCATATGATTGCTCAAGTGTGTGGCTTAGGCGTTGGTG
ATTTTGTTTGGACAGGTGGCGATATACATCTTTATGCCAACCATTTTGAGCAGGCAAAACTACAATTGATGCGTGAGCCA
TTACCACTTTGCCAATTAAAACTTAATCCAGATGTTAAAGATATTTTCGACTTCAAATTTGAAGATATCGAGATTGTAGG
TTACGAGTCACATCCGGCAATTAAAGCACCAGTTGCAGTATAA

Protein sequence :
MRAYLDLLQHILDNGGDKGDRTGTGTRSVFGHQMRFDLSKGFPLLTTKKVHFRSIVIELLWFLKGDTNVKYLQDNKVTIW
DEWATAEQTARFGRPEHELGPVYGHQWRNFGATKNADGTYNQDGFDQIKWLINEIKTNPNSRRLIVSGWNPNEAGQVALP
PCHTLFQFFVQDNKLSCQLYQRSADVFLGVPFNIASYALLTHMIAQVCGLGVGDFVWTGGDIHLYANHFEQAKLQLMREP
LPLCQLKLNPDVKDIFDFKFEDIEIVGYESHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-67 58
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-65 51