Gene Information

Name : leuS (ABSDF2980)
Accession : YP_001708122.1
Strain : Acinetobacter baumannii SDF
Genome accession: NC_010400
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2738807 - 2741431 bp
Length : 2625 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTATTTCTCACATTGACCCAGAATATCAAGCAAACACGATTGAACCATCAGTCCAACAAGATTGGGAAAATCGTAA
AGTCTTTAAAGTTGCCGACACTGTCGAAGGTAAACATCGCTACATCCTGTCAATGTTCCCTTACCCAAGTGGCAAACTGC
ACATGGGTCATGTGCGTAACTATACCATTGGCGATGTAATTAGCCGTTTTTACCGTTTAAAAGGTGAAACCGTATTACAA
CCTATGGGTTGGGATGCATTTGGTTTACCAGCGGAAAACGCTGCAATTGCCCATAAAGTTGCTCCGGCAAAATGGACATT
TGAAAACATCGCTTACATGCGTGACCAATTAAAAAAATTAGGTCTATCTGTAGATTGGGACCGTGAATTTGCAACGTGTA
CACCAGAGTACTATCACTGGGAACAATGGTTGTTTGTTCAGCTTTATAAAAAAGGTTTAATCTACCGTAAACTTTCAACA
GTAAACTGGGACCCGGTTGACCAAACAGTTTTGGCAAACGAACAAGTTGAAAATGGTCGTGGCTGGCGTTCAGGTGCATT
GGTTGAAAAACGCGATATTCCAATGTACTACTTCCGTATTACGGACTATGCACAAGAATTATTAGACGACCTAGACACTC
TACAAGACGGCTGGCCTCAACAAGTGTTGACCATGCAGCGTAACTGGATTGGTCGTTCTACAGGTATGGAAATTACCTTC
CCATCTGCCAATACTGAAATTTATGCTGACGGCTTAACTGTTTATACAACACGTGCCGACACACTTATGGGTGTGACGTA
CGTTGCCGTTGCAGCAGAACACCCTCTTGCGCTTAAAGCTGCTGAAAATAACCCTGAATTGGCTGCATTTATTGAAGAAT
GCCGCATAGGTTCAGTTGCAGAAGCTGACTTGGCTACAGCCGAGAAGAAAGGTATGGCAACAGGTTTGTTTGTAAAACAC
CCTGTAACTGGCGAAGAGCTTCCTGTCTGGATTGCGAACTACGTATTAATGTCTTACGGTTCTGGCGCAGTGATGGCTGT
ACCAGCACATGACGAACGTGACTTTGAATTTGCTAACAAGTTCAACTTGCCAATTAAGCAAGTGATTGATGCCAAAGGTG
CTGACGATGCGGATTATTCTGCTACCGAGTGGCAAGAATGGTACGGTTCTAAAGAAGGTAAACTTGTTAACTCTGGCGAA
TTTGACGGTCTAGAATTCCAAGCTGCATTCGATGCATTCCTTGCAAAATTAGAACCACAAGGTTTAGCAAATTCTAAAGT
TCAATTCCGTTTACGTGACTGGGGTGTTTCTCGTCAACGTTACTGGGGTTGTCCAATTCCAATGATTAACTGTGATACTT
GTGGTCAAGTCACAGTTCCTGAAGATCAACTTCCGGTTGTATTACCAACTGACGTTGTTCCAGATGGTTCAGGTAATCCA
CTAAATAAAATGCCTGAATTCTATGAAACGAAATGTCCTTGCTGTGGTGGCGATGCACGCCGTGAAACAGATACATTGGA
CACATTCGTAGAATCATCTTGGTACTACGCACGCTATGCATCTCCAGACTTTACTGGTGGTATAGTAAAACCTGAAGCAG
CTAAAAACTGGCTTCCTGTAAACCAATATATTGGTGGTGTTGAACACGCGATTCTTCACTTACTTTATGCACGTTTCTTC
CACAAATTAATGCATGATGAAGGTGTTGTACAAGGTAATGAACCATTTACCAACTTGTTAACTCAAGGCATGGTGCTTGC
AGATACTTTCTATCGTGAAGCAGAAAATGGTAAGAAAACTTGGTTCAACCCTGCTAACATCGAATTAGAACGTGATGAGA
AAGGTCGCATCATTTCTGCAAAATATTCAGGTGATGGTCAAGAAGTGATTATCGGCGGACAAGAAAAAATGTCCAAGTCG
AAAAATAACGGTATTGACCCACAAGCCATTATTGATCAATACGGCGCAGATACAGCTCGTGTATTTATGATGTTTGCTGC
ACCACCAGATCAATCTTTAGAATGGTCTGATGCAGGTGTTGAAGGTGCAAACCGTTTCTTGAAACGTGTATGGCGTTTGG
TAGCAAGCTTCCTTGAAAAAGGAAACTCTGCAACAGCAATCGATAAAGCAAACTTGTCTAAAGATGCTCAAGATTTACGT
CGTAAGACACACGAAACCATTCAAAAAGTAAGTGATGATATTGAGCGTCGTCATGCGTTCAATACTGCAATTGCTGCATT
GATGGAATTGTTAAACGCAAGCAATAAGTTTGAAGCAAAAGATGACAATGACGTTGCTGTAGAACGTGAAGCAATCACCA
CATTGTTAACGTTACTTGCTCCATTTGCTCCGCATTTAAGCCAGACTTTATTGGCTCAGTTTGGTACGGACTTAACAGAA
GCAACTTTCCCTGAAGTTGATGCTTCTGCATTAACCCGCAATACTCAAACGATTGTTGTACAAGTAAATGGTAAACTTCG
CGGTAAACTTGAAGTTTCTGTTGATATTTCTAAAGATGAGTTATTAGCTCAAGCGAAAGCATTACCAGAAGTTCAGCAGT
TCTTAACAGGACCAACCAAAAAAGAGATTGTGGTTCCAAACAAATTGGTTAACCTCGTGGTTTAA

Protein sequence :
MTISHIDPEYQANTIEPSVQQDWENRKVFKVADTVEGKHRYILSMFPYPSGKLHMGHVRNYTIGDVISRFYRLKGETVLQ
PMGWDAFGLPAENAAIAHKVAPAKWTFENIAYMRDQLKKLGLSVDWDREFATCTPEYYHWEQWLFVQLYKKGLIYRKLST
VNWDPVDQTVLANEQVENGRGWRSGALVEKRDIPMYYFRITDYAQELLDDLDTLQDGWPQQVLTMQRNWIGRSTGMEITF
PSANTEIYADGLTVYTTRADTLMGVTYVAVAAEHPLALKAAENNPELAAFIEECRIGSVAEADLATAEKKGMATGLFVKH
PVTGEELPVWIANYVLMSYGSGAVMAVPAHDERDFEFANKFNLPIKQVIDAKGADDADYSATEWQEWYGSKEGKLVNSGE
FDGLEFQAAFDAFLAKLEPQGLANSKVQFRLRDWGVSRQRYWGCPIPMINCDTCGQVTVPEDQLPVVLPTDVVPDGSGNP
LNKMPEFYETKCPCCGGDARRETDTLDTFVESSWYYARYASPDFTGGIVKPEAAKNWLPVNQYIGGVEHAILHLLYARFF
HKLMHDEGVVQGNEPFTNLLTQGMVLADTFYREAENGKKTWFNPANIELERDEKGRIISAKYSGDGQEVIIGGQEKMSKS
KNNGIDPQAIIDQYGADTARVFMMFAAPPDQSLEWSDAGVEGANRFLKRVWRLVASFLEKGNSATAIDKANLSKDAQDLR
RKTHETIQKVSDDIERRHAFNTAIAALMELLNASNKFEAKDDNDVAVEREAITTLLTLLAPFAPHLSQTLLAQFGTDLTE
ATFPEVDASALTRNTQTIVVQVNGKLRGKLEVSVDISKDELLAQAKALPEVQQFLTGPTKKEIVVPNKLVNLVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-137 41