Gene Information

Name : lysS (ABSDF2397)
Accession : YP_001707649.1
Strain : Acinetobacter baumannii SDF
Genome accession: NC_010400
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2218504 - 2220033 bp
Length : 1530 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACGCAACAAAACGCTCAATCGACTTCTGAACCAACTATTTCCGAAAACGATTTAATTGCACAGCGTCATGCCAAATT
AAAGCAAATCCAAGATGTTGCAAAGGAAACTGGAAAGAGTCCTTGGCCAAATACATTCAAACGTGAACATTACGCTGCTG
ATTTACAAGAACAATTTAAAGATCAGTCTAAAGAACAAATCGAAAGTGCTGAACATGTTTATGTAAAAGTTGCTGGCCGT
GTCATGTTAAACCGTGGTTCTTTCATGGTGATTCAAGACATGACTGGTCGTATCCAATTATATGTTGACCGTAAGGGTTT
ACCAAAAGATACGCTCGAAACTATTAAAGGTTTAGACCTTGGCGATATTATTGCTGCTGAAGGTTATATCGGTCGTTCTG
GCAAAGGTGACTTATATGTACACCTTGAAGGTTTTGAACTTCTTACAAAATCGCTTCGTCCATTGCCGGATAAATTTCAT
GGTTTGAACGACACAGAAGTTAAATATCGTAAGCGTTATCTTGACTTAATTGTGAATGAAGAAACGCGTAAGACTTTTGA
AATTCGTGCCAAAGTCGTTGCAGGTATTCGCGCATTTTTAACCAATGAACGTTTCATGGAAGTTGAAACGCCAATGATGC
ATGTGATTCCGGGTGGCGCGTCTGCACGTCCGTTTGAAACGCATCATAATGCTTTAGATATGCCATTATTCTTGCGTATC
GCACCTGAGCTTTATTTAAAGCGTTTAGTAGTGGGTGGTTTTGAGCGTGTGTTCGAAATTAACCGTAACTTCCGTAATGA
AGGGGTGTCAACACGTCATAACCCTGAATTTACCATGATCGAGTTTTATCAGGCATATGCTGATTATAAAGACTTGATGG
CTTTAACTGAAAACATGCTTGAAAAGTTAGCTCTTGATATTTTAGGTACAACTGATGTGCCTTACCAAGGTGAAGTGTTT
AGCTTTAAAGGACCATTCAAGAAAATCTCTATGTTTGATGCGATTTTGGAGAATAATCCGCAGTTCACGCCTGAAAATGT
AGGCGATCGTGAATTCCTTGCAAAATTTGTTCGTGAGGAATTAAAAGAAGAAGTTAAACCTGGTTTTGGTTTAGGTAAGC
TTCAAACAATCGTATTTGAAGAAACGGTTGAGACTAAACTTCGTCAGCCTACTTTTATTACTGAGTACCCAGCAGAGACT
TCTCCACTTGCTCGCCGTAATGATGATAATCCGCACATTACTGATCGTTTTGAGTTCTTTATTGGTGGCCGTGAATTGGC
AAACGGCTTTAGTGAGTTAAATGATCCGATTGATCAGGCTGAACGTTTCCAAGCGCAAGTTGCTGAAAAAGATGCTGGTG
ATGATGAAGCAATGCATTACGATGCAGAGTTTGTTGAAGCACTTGAATATGGTTTACCTCCAACAGCGGGTGAAGGTATT
GGTATTGACCGTTTGGTTATGCTTTTTGCAGATGCACCAAGTATTCGTGATGTGATTTTGTTCCCGCATATGCGTCGTAA
AGAAGGTTAA

Protein sequence :
MTQQNAQSTSEPTISENDLIAQRHAKLKQIQDVAKETGKSPWPNTFKREHYAADLQEQFKDQSKEQIESAEHVYVKVAGR
VMLNRGSFMVIQDMTGRIQLYVDRKGLPKDTLETIKGLDLGDIIAAEGYIGRSGKGDLYVHLEGFELLTKSLRPLPDKFH
GLNDTEVKYRKRYLDLIVNEETRKTFEIRAKVVAGIRAFLTNERFMEVETPMMHVIPGGASARPFETHHNALDMPLFLRI
APELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEFYQAYADYKDLMALTENMLEKLALDILGTTDVPYQGEVF
SFKGPFKKISMFDAILENNPQFTPENVGDREFLAKFVREELKEEVKPGFGLGKLQTIVFEETVETKLRQPTFITEYPAET
SPLARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVAEKDAGDDEAMHYDAEFVEALEYGLPPTAGEGI
GIDRLVMLFADAPSIRDVILFPHMRRKEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-128 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001707649.1 lysyl-tRNA synthetase VFG1668 Protein 1e-128 55