Gene Information

Name : guaA (ABSDF0144)
Accession : YP_001705882.1
Strain : Acinetobacter baumannii SDF
Genome accession: NC_010400
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 140047 - 141615 bp
Length : 1569 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTACCAATACTCAAATTACTGAAGATCGTATCCTGATCCTGGATTTCGGCTCTCAATATAGTCAGCTCATTGCACG
TCGTGTACGTGAAGCTGGTGTTTACTCTGAAATGTATGCCTTTGATATGTCTGAAGAAGACATCCGTGCTTTTAAGCCAA
ACGGTATCATTTTATCAGGTGGACCTGAGAGTGTGCATGAAGAGGGCAGCCCTCGCGCACCGCAAGTGGTGTTTGAATTA
GGCGTTCCAGTATTGGGTATTTGCTATGGTTTACAAACCATGTCTGAACAGTTAGGCGGTAAAGTTGAGCTGGGTACTGT
ACATGAGTTTGGTTATGCTGAAGTTGATATCGTTAAACGTGACCAACTCATTGGCAACTTACAAGACCGCGAAAACCAAC
TACACGTTTGGATGAGCCACGGCGACAAAGTGAGCCAGATTCCAGAAGGTTTTACGATTACTGCAAGCACACCAAGCTGT
CCAGTTGCTGCTGTAAGTGATGAAACACGCCGTTTTTACGGTGTTCAGTTCCACCCAGAAGTAACACACACGGCAAAAGG
TGAAGAGCTACTTTCTAATTTCGTTCACAAAATTTGTGGATGCGGTGGCCTTTGGACACCTGAACACATCATCGATTTGC
GTGTAGAGCAGTTACGGGAGCAAATTGGTAACGAGAAAGTACTTTTAGGCCTGTCTGGTGGTGTTGACTCATCTGTTGTT
GCTGCGCTTTTACACAAAGCGATTGGTGACCAATTAACATGTGTATTTGTTGATAATGGTTTGCTTCGTTTAAACGAAGG
TGACCAAGTGATGCAAATGTTTGCTGAAAACATGGGTATTCGTGTTATTCGTGCGGATGCAGAAGCGCGCTTCTTAAATG
CTCTAGCTGGCGTTACCGATCCTGAAGCGAAGCGTAAAATTATTGGTCGTGAGTTTATTGAAGTATTTGCTGAAGAAGCA
CGTAAACTTGATGGCGTGAAATTCTTGGCGCAAGGTACAATTTACCCAGACGTAATTGAATCTGCTGCAAGCAAACAAGG
TAAAGCACACGTTATTAAATCTCACCACAATGTGGGTGGTTTACCAGACGATTTAGCATTTGAATTGGTTGAGCCTTTAC
GTGACTTGTTTAAAGATGAAGTACGTAAATTAGGTACTACACTTGGCTTGCCACATAGCATGATCTACCGTCATCCCTTC
CCGGGCCCAGGTTTAGGCGTTCGTATTTTGGGTGAAGTGAAAAAAGAATATGCAGATATTCTTCGCCTTGCTGATGATAT
CTTTATGCAAGAGCTTCGTGACAGCGGCTGGTATGGCAAAACAGCTCAAGCATTTGCTGTATTCCAACCTGTTAAATCAG
TAGGTGTAGTCGGTGATGGCCGTCGCTATGCATGGGTGATTGCGCTTCGTGCAGTTGAAACAGTTGACTTTATGACAGCT
CGTTTTGCACATTTACCATACGAATTGGTTGATAAAATCTCAACACGTATTATGAACGAAATTAAAGATGTATCACGTGT
GGTATACGATGTGTCATCTAAACCACCAGCAACGATTGAGTGGGAATAA

Protein sequence :
MTTNTQITEDRILILDFGSQYSQLIARRVREAGVYSEMYAFDMSEEDIRAFKPNGIILSGGPESVHEEGSPRAPQVVFEL
GVPVLGICYGLQTMSEQLGGKVELGTVHEFGYAEVDIVKRDQLIGNLQDRENQLHVWMSHGDKVSQIPEGFTITASTPSC
PVAAVSDETRRFYGVQFHPEVTHTAKGEELLSNFVHKICGCGGLWTPEHIIDLRVEQLREQIGNEKVLLGLSGGVDSSVV
AALLHKAIGDQLTCVFVDNGLLRLNEGDQVMQMFAENMGIRVIRADAEARFLNALAGVTDPEAKRKIIGREFIEVFAEEA
RKLDGVKFLAQGTIYPDVIESAASKQGKAHVIKSHHNVGGLPDDLAFELVEPLRDLFKDEVRKLGTTLGLPHSMIYRHPF
PGPGLGVRILGEVKKEYADILRLADDIFMQELRDSGWYGKTAQAFAVFQPVKSVGVVGDGRRYAWVIALRAVETVDFMTA
RFAHLPYELVDKISTRIMNEIKDVSRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-141 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-141 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-141 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-117 51