Gene Information

Name : MAB_0972 (MAB_0972)
Accession : YP_001701718.1
Strain : Mycobacterium abscessus ATCC 19977
Genome accession: NC_010397
Putative virulence/resistance : Virulence
Product : Putative aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 979033 - 980553 bp
Length : 1521 bp
Strand : +
Note : Similar to Q5YVE9_NOCFA 0.0

DNA sequence :
ATGGCGAAGTACGCGGCACCCGGAACCGAGGGCAGTGCAGTCACTTTCGCGCCCAGGTACGACAACTTCATCGGCGGGGA
ATGGGTTGCCCCGGCGGATGGCCAGTACTTCGAGAACGCCTCTCCGATCGACGGCAAGGTGTTCACCCGGGTTGCCCGCG
GTACCGCGCCGGATATCGAGAAGGCGCTGGACGCGGCGCACGCCGCGGCCGAGGCGTGGGGTAACACCTCGGCCGCTGAA
CGGTCGAACGCCTTGCTGCGGATCGCCGACCGGATGGAACAGCACATCGAGAGGCTCGCGGTCGCCGAAACCTGGGATAA
CGGCAAGCCGATTCGGGAAAGCCTGAACGCTGATATCCCGCTGGCAATCGATCACTTCCGCTACTTCGCCGGCGTGCTCC
GAGCCCAAGAGGGTTCGATCTCCGAGATTGACCACGACACCGTGGCCTATCACTTCCATGAGCCGCTGGGCGTTGTCGGG
CAGATCATCCCGTGGAACTTCCCCCTGTTGATGGCCGTGTGGAAGCTGGCTCCGGCGCTGGCGGCGGGCAACTGTGTGGT
GCTCAAGCCCGCCGAACAGACGCCCGCCTCGATCCTGGTGCTGATGGAGCTGATTGCCGACTTGCTGCCATCCGGAACCG
TCAACGTGGTCAACGGTTTTGGTGTGGAGGCGGGTAAGCCGCTGGCCTCCAGTCCGCGCATCGCCAAGATCGCGTTTACC
GGCGAGACCACCACGGGGCGCCTCATCATGCAGTACGCGACGGAGAACATCATCCCGGTCACGCTGGAACTCGGCGGTAA
GAGCCCCAACATCTTCATGCCCGACGTGATGGCCGCCGACGACGCCTTCCTGGACAAGGCGCTTGAGGGCTTCACCATGT
TCGCGCTCAACCAGGGTGAGGTGTGCACCTGCCCCTCGCGTGCGTTGGTGCACGCATCCATCTACGACGAGTTCATCGCG
CGTGCCATCACGCGCGTGGAGGCGATCGTAGGCGGTGATCCGCTCGACGAAGACACCATGATCGGTGCGCAGGCAAGCAA
TGACCAATATGAAAAGATCTTGTCGTACATCGATATTGGGCGGCAAGAGGGTGCGCAGGTACTGACCGGCGGAGATGCGC
GCAAGGTTTCCGAATATCCCGACGGCGCCTACATCCAGCCCACGGTGTTCGCCGGTACCAACAACATGCGCATCTTCCAG
GAGGAGATTTTCGGCCCGGTGCTGTCGGTGGCGAAGTTCGACTCATTGGATGAGGCATTGAAGATCGCCAACGACACCCT
GTATGGCCTCGGCGCCGGGGTGTGGTCGCGCGATATGACCAACGCCTACCGGCTGGGTCGCGGTATCAAGGCCGGGCGGG
TGTGGACCAACTGCTACCACCAGTACCCGGCGCATGCCGCTTTCGGCGGCTACAAGAAGTCGGGCATCGGGCGTGAGAAC
CACAAGATGATGCTCGACCACTATCAGCAGACCAAGAACATCTTGGTGAGCTATTCGCCCGATGCCGCGGGCTTCTTCTG
A

Protein sequence :
MAKYAAPGTEGSAVTFAPRYDNFIGGEWVAPADGQYFENASPIDGKVFTRVARGTAPDIEKALDAAHAAAEAWGNTSAAE
RSNALLRIADRMEQHIERLAVAETWDNGKPIRESLNADIPLAIDHFRYFAGVLRAQEGSISEIDHDTVAYHFHEPLGVVG
QIIPWNFPLLMAVWKLAPALAAGNCVVLKPAEQTPASILVLMELIADLLPSGTVNVVNGFGVEAGKPLASSPRIAKIAFT
GETTTGRLIMQYATENIIPVTLELGGKSPNIFMPDVMAADDAFLDKALEGFTMFALNQGEVCTCPSRALVHASIYDEFIA
RAITRVEAIVGGDPLDEDTMIGAQASNDQYEKILSYIDIGRQEGAQVLTGGDARKVSEYPDGAYIQPTVFAGTNNMRIFQ
EEIFGPVLSVAKFDSLDEALKIANDTLYGLGAGVWSRDMTNAYRLGRGIKAGRVWTNCYHQYPAHAAFGGYKKSGIGREN
HKMMLDHYQQTKNILVSYSPDAAGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-150 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-158 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-158 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-158 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-158 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-75 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_0972 YP_001701718.1 Putative aldehyde dehydrogenase VFG0082 Protein 1e-150 63