Gene Information

Name : MAB_0546 (MAB_0546)
Accession : YP_001701299.1
Strain : Mycobacterium abscessus ATCC 19977
Genome accession: NC_010397
Putative virulence/resistance : Virulence
Product : Probable ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 546836 - 549370 bp
Length : 2535 bp
Strand : +
Note : Similar to CLPC_MYCBO 0.0

DNA sequence :
ATGTTCGAGAGATTCACTGACCGCGCCAGGCGGGTGGTTGTGCTGGCCCAAGAAGAGGCCCGCATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGTCTGATCCATGAGGGCGAGGGCGTCGCCGCCAAGTCGCTCGAGTCGTTGGGCA
TCTCGCTGGAAGGGGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGTCAGCAGGCGCCGTCCGGGCACATTCCGTTC
ACTCCGCGTGCCAAGAAGGTGCTGGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATTCGCGAGGGCGAGGGCGTTGCCGCACAGGTGCTCGTCAAGCTGGGCGCCGAGCTGACTCGGG
TGCGTCAGCAGGTCATCCAGCTGCTCAGTGGCTACCAGGGCAAGGAGACCGCAGAATCGGGTACCGGTGGCAGGGGCGGA
GAAGCCGGCACACCTTCTACGTCGCTGGTGCTCGACCAGTTCGGCCGCAATCTGACCGCGGCCGCCATGGAGGGCAAGCT
CGATCCGGTCATCGGCCGTGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGTGTCGGCAAGACCGCCGTCGTCGAGGGTCTGGCCCAGGCGATCGTGCACGGCGAGGTGCCCGAG
ACACTGAAGAACAAGCAGCTGTACACCTTGGACCTGGGGTCCCTGGTGGCCGGCAGCCGCTACCGCGGTGATTTCGAGGA
ACGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGTGGTGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTGG
GTGCGGGCGCGGCCGAGGGCGCGATCGACGCGGCCTCGATCCTGAAGCCGAAGCTGGCTCGTGGCGAGCTGCAGACCATC
GGTGCGACCACACTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAGCGCCGGTTCCAGCCGGTGCAGGT
GGGCGAGCCGACGGTCGAGCACACCATCGAGATCCTCAAGGGTCTACGCGACCGCTACGAGGCACACCACCGGGTGTCCA
TCACCGATGGCGCATTGGTTGCCGCGGCGACCCTGGCCGATCGGTACATCAACGACAGGTTCTTGCCCGACAAGGCGATC
GACCTGATCGACGAGGCCGGTGCCCGCATGCGCATCCGCCGCATGACCGCGCCGCCAGACCTGCGCGAGTTCGACGAGAA
GATCGCCGATGCGCGCCGGGAGAAGGAATCGGCCATCGACGCGCAGGACTTCGAGAAGGCCGCGCGCCTGCGCGACTCCG
AGAAGCAGCTGGTGGCCCAGCGTGCCGATCGCGAAAAGCAATGGCGTTCAGGTGACTTAGATGTGGTCGCGGAAGTCGAT
GATGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGTATCCCCGTGTTCAAGCTGACCGAGGAAGAAACCACTCGGCT
GCTGCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCCGTCTCCAAGGCCATCCGCC
GCACCCGTGCCGGTCTGAAGGACCCGCGGCGCCCCTCGGGCTCGTTCATCTTCGCCGGGCCGTCCGGTGTCGGTAAGACC
GAGCTGTCCAAGGCGCTGGCCAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCCTCAAGGCTTTTCGGCGCTCCCCCGGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGGAAGCCGTTCAGCGTGGTGTTGTTCGACGAGATCGAGAAGGCTCACCAGGAGATCTACAACACCCTGTTGCAG
GTTCTCGAGGACGGTCGCCTCACCGACGGCCAGGGACGCACGGTCGATTTCAAGAACACCGTGCTGATCTTCACCTCGAA
CCTGGGCACGTCGGATATCTCGAAGGCCGTCGGCCTCGGATTCTCCGAAGGTGCGGCCGGCTCGAACTACGAGCGGATGA
AGCAGAAGGTCCACGACGAGCTCAAGAAGCACTTCCGTCCTGAGTTCCTCAACCGCATCGATGACATCATCGTCTTCGAG
CAGCTGACGCAGGAACAGATCATCGAGATGGTCGACCTGATGATCGGGCGGGTGGGCAAGCAGCTCAAGACCAAAGACAT
GGCCATGGAGCTCACCGACAAGGCCAAGTCGCTGCTGGCCAAGCGCGGATTCGATCCGGTGCTAGGCGCCCGCCCGCTGC
GTCGGACCATTCAGCGCGAGATCGAGGACGCACTCTCGGAGAAGATTCTCTTCAACGAGGTCGGTCCCGGCGAGCTGGTC
ACCGTCGACGTCGAGAACTGGGACGGCGAGAGTGCCGGCGAGGACGCGAAGTTCACCTTCGTCGGCCGTCCGAAGCCCGC
ACTGGTCGCCGGTGAGGAGCCTGCCGCCGACCTGGCCGCCTCCGCCTCGGAGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAESGTGGRGG
EAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKNKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARLRDSEKQLVAQRADREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDELKKHFRPEFLNRIDDIIVFE
QLTQEQIIEMVDLMIGRVGKQLKTKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGELV
TVDVENWDGESAGEDAKFTFVGRPKPALVAGEEPAADLAASASE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 83

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_0546 YP_001701299.1 Probable ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 60
MAB_0546 YP_001701299.1 Probable ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 6e-147 50