Gene Information

Name : MAB_3591c (MAB_3591c)
Accession : YP_001704320.1
Strain : Mycobacterium abscessus ATCC 19977
Genome accession: NC_010397
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator MtrA
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3641100 - 3641777 bp
Length : 678 bp
Strand : -
Note : Similar to MTRA_MYCPA e-105

DNA sequence : 
ATGAGGCAAAGGATCCTTGTTGTCGACGATGACGCGTCATTGGCGGAGATGCTCACCATCGTGTTGCGCGGGGAGGGCTT
CGAGACCGCGGTCGTGAGCGATGGCACCCAGGCGCTCACCGCCGTCCGGGAGCTGCGCCCCGACCTGGTCTTGTTGGACC
TCATGCTGCCGGGGATGAACGGCATCGATGTATGCCGCGTGCTGCGCTCCGACTCCGGAGTGCCGATCGTCATGCTTACC
GCCAAGACCGACACCGTGGATGTGGTGTTGGGCCTGGAGTCTGGTGCTGACGACTACATCATGAAGCCGTTCAAGCCCAA
GGAACTCGTGGCCCGCATCCGTGCCCGGCTGCGGCGAAACGACGACGAGCCCGCCGAACTGCTGAACATCGCGGGTATCG
ACATCGACGTGCCCGCGCACAAGGTGACGCGCGAGGGCGAGCAGATCTCGCTGACCCCGCTGGAGTTCGACCTGCTGGTG
GCGCTGGCACGCAAACCGCGCCAGGTGTTTACTCGAGATGTGCTGCTCGAACAGGTGTGGGGTTACCGTCACCCGGCCGA
TACCAGGCTGGTGAACGTCCACGTGCAGCGTCTGCGGGCGAAGGTCGAGAAGGACCCCGAGAATCCGACCGTGGTGTTGA
CCGTTCGAGGAGTGGGATATAAGGCCGGACCCCCGTGA

Protein sequence : 
MRQRILVVDDDASLAEMLTIVLRGEGFETAVVSDGTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRSDSGVPIVMLT
AKTDTVDVVLGLESGADDYIMKPFKPKELVARIRARLRRNDDEPAELLNIAGIDIDVPAHKVTREGEQISLTPLEFDLLV
ALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 1e-34 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 7e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA AE000516.2.gene3505. Protein 3e-83 96
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002952.2859905.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_009641.5332272.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_013450.8614421.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002951.3237708.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_007793.3914279.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002745.1124361.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_009782.5559369.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_007622.3794472.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002758.1121668.p0 Protein 5e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_003923.1003749.p0 Protein 4e-41 46
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002951.3238224.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_007793.3914065.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002758.1121390.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_010079.5776364.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002952.2859858.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_007622.3794948.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_003923.1003417.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_013450.8614146.p0 Protein 1e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA AE015929.1.gene1106. Protein 4e-32 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA HE999704.1.gene2815. Protein 2e-35 44
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA BAC0125 Protein 6e-30 43
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_012469.1.7685629. Protein 7e-36 42
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA CP000034.1.gene3671. Protein 1e-31 42
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_002695.1.916589.p Protein 1e-30 42
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA BAC0111 Protein 2e-27 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA NC_012469.1.7686381. Protein 5e-38 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA HE999704.1.gene1528. Protein 1e-28 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA AF155139.2.orf0.gene Protein 4e-30 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA BAC0197 Protein 1e-28 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA CP004022.1.gene1676. Protein 1e-27 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA CP001138.1.gene2239. Protein 2e-29 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA BAC0596 Protein 2e-29 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA CP001918.1.gene3444. Protein 6e-31 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA CP000034.1.gene2186. Protein 1e-30 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA BAC0039 Protein 1e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA VFG1390 Protein 2e-31 43
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA VFG1389 Protein 1e-28 43
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA VFG1563 Protein 7e-35 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA VFG1702 Protein 2e-34 41
MAB_3591c YP_001704320.1 DNA-binding response regulator MtrA VFG1386 Protein 5e-28 41