Gene Information

Name : MAB_2639c (MAB_2639c)
Accession : YP_001703373.1
Strain : Mycobacterium abscessus ATCC 19977
Genome accession: NC_010397
Putative virulence/resistance : Virulence
Product : Probable pyruvate kinase PykA
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2680601 - 2682019 bp
Length : 1419 bp
Strand : -
Note : Similar to Q740P0_MYCPA 0.0

DNA sequence :
GTGACGAGACGCGGAAAGATCGTTTGTACCCTCGGTCCTGCGACCGGTTCGGCCGAGCTTGTGCGCGCGCTCGTCGAGGC
CGGTATGGATGTCGCACGGTTGAACTTCAGCCACGGCGAGCACGCTGACCACGAGCAGAACTACCGCTGGGTGCGCAAGG
CATCCGATGAGTCCGGGCGGGCGGTCGGCGTGCTCGCCGATCTTCAGGGCCCCAAGATCAGGCTGGGCAGATTCGCTACC
GGGTCCGCCCACTGGGCCACCGGCGAACAGGTCCGGATCACCGTTGAGGACGTGGTAGGCACCCCGGACCGGGTTTCCAC
CACCTACAAGCAGTTGGCGGCGGATGCTGCCGTCGGCGACAGGCTCCTGGTCGACGATGGCAAGGTCGGCCTGACGGTCG
AAGCAATCGAGGGCGATGACGTCGTTTGCCGGGTGACCGAGGGGGGACCGGTCAGCAACAACAAGGGGTTGTCGCTGCCG
GGCATGAACGTCTCGGTGCCGGCCCTTTCCGAGAAGGACATCGCCGACTTGGAGTTCGCGCTGCGGCTCGGCGTCGATCT
CATCGCCCTGTCCTTCGTGCGCTCGCCCAGCGATGTGGAGCTGGTGCACGCCGTCATGGACCGTGTGGGACGCCGCGTGC
CGGTGATCGCCAAGCTGGAGAAGCCGGAGGCCGTCGCCAACCTCGAGGCGATCGTGTTGGCCTTCGACGCGATCATGGTC
GCCCGCGGGGATCTCGGTGTGGAGCTGCCGCTGGAAGATGTGCCCATTGTGCAGAAGCGGGCTATCCAGATCGCTCGGGA
AAACGCGCGCCCGGTCATCGTGGCCACCCAGATGCTCGAGTCGATGATCGAGAATTCGCGGCCCACCCGCGCCGAGGCCT
CCGATGTGGCCAACGCGGTCCTGGATGGTGCCGACGCCGTGATGCTGTCGGGGGAGACCTCGGTGGGCAAGTATCCGCTG
GAGGCGGTGCGGACCATGGCCCGCATCGTGTCCGCGGTGGAGAGCCATTCGGTGAGTGCGCCGCCGCTGACCCATGTTCC
GCGCACCAAACGTGGGGTCATCTCGTACGCGGCACGCGACATCGGGGAGCGCCTCAACGCCAAGGCCCTGGTCGCCTTCA
CGCAGTCCGGCGATACCGTCCGCCGGCTGGCCCGGCTGCATACTCCACTGCCGGTGCTGGCCTTCACCCCGCTGCCGGAG
GTGCGTAGCCAGCTGGCACTCACGTGGGGGACGGAAACCTTCATCGTCCCGGTCATGGAGACCACCGACGGCATGATTCA
ACAGGTGGATACGGCATTGCTGGAGATGGAGCGCTATCAGCGGGGAGATCTCGTGGTGATCGTCGCGGGCGCCCCACCCG
GGACAGTAGGCTCGACCAATCTGATCCACGTGCACCGGATCGGCGAGGACGACCACTAG

Protein sequence :
MTRRGKIVCTLGPATGSAELVRALVEAGMDVARLNFSHGEHADHEQNYRWVRKASDESGRAVGVLADLQGPKIRLGRFAT
GSAHWATGEQVRITVEDVVGTPDRVSTTYKQLAADAAVGDRLLVDDGKVGLTVEAIEGDDVVCRVTEGGPVSNNKGLSLP
GMNVSVPALSEKDIADLEFALRLGVDLIALSFVRSPSDVELVHAVMDRVGRRVPVIAKLEKPEAVANLEAIVLAFDAIMV
ARGDLGVELPLEDVPIVQKRAIQIARENARPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPL
EAVRTMARIVSAVESHSVSAPPLTHVPRTKRGVISYAARDIGERLNAKALVAFTQSGDTVRRLARLHTPLPVLAFTPLPE
VRSQLALTWGTETFIVPVMETTDGMIQQVDTALLEMERYQRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_2639c YP_001703373.1 Probable pyruvate kinase PykA VFG0479 Protein 7e-78 41