Gene Information

Name : MAB_2425 (MAB_2425)
Accession : YP_001703160.1
Strain : Mycobacterium abscessus ATCC 19977
Genome accession: NC_010397
Putative virulence/resistance : Virulence
Product : Urease, alpha subunit (UreC)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 2481754 - 2483487 bp
Length : 1734 bp
Strand : +
Note : Similar to Q276Y1_MYCFV 0.0

DNA sequence :
GTGACCAGGCTGACGCGGGAGCATTACGCGAAGCTTTACGGCCCGACGACAGGCGATCGCATCCGCCTGGCCGATACCGA
TCTGATCATCGAGATCACCGAAGACCGTTGCGGCGGACCTGGTTTGGCCGGTGAGGAGGCGGTCTTCGGTGGAGGCAAGG
TGTTACGGGAGTCGATGGGGCAGAGCCGCCTCACCCGTGCCGGCGGCGCTCCGGATACCGTTATCACCGGTGCGATCATC
ATCGACCACTGGGGAATCATTAAGGCCGACATCGGTATCCGCGACGGTCGTATCGTCGGTATCGGCAAGGCGGGAAACCC
GGACATCATGGACGGGGTGGACCCCGCCCTGATCGTGGGGCCGTCAACCGAGATCATCGCCGGTAACAACAGGATCGTGA
CTGCCGGCGGCATCGACTGTCACGTGCACTTCATCTGTCCACAGATCCTGCCGGAGGCGCTGAGTGGCGGCATCACCACG
ATGATCGGTGGCGGTACCGGGCCCGCCGAGGGTAGTAAGGCCACTACCGTCACACCGGGAGCTTGGCATCTGGGCCGGAT
GCTACAGGCGCTCGACGGCTGGCCCATGAACATTCTGATGCTCGGCAAGGGGAATACCGTCAATCCAGATGCCATGTGGG
AGCAATTGCGTGGCGGCGCAGCGGGTTTCAAACTGCACGAAGATTGGGGAACCACCCCGGCGGTGATCGACGCCTGCCTG
CGGGTAGCGGACGAGGCCGACGTGCAAGTCGCCTTGCACTCGGACACTCTCAACGAGACCGGATTTGTGGAAGGCACACT
GGCGGCGATCGGCGGGCGGGCGATCCACGCGTACCACACCGAGGGGGCCGGTGGCGGTCACGCGCCCGACATCATCACCG
TCGCCAGCCACCCGAATGTCATGCCCAGTTCCACGAACCCGACTCGCCCGCACACGGTGAACACCCTCGACGAGCATCTC
GACATGCTCATGGTTTGCCACCACCTCAACGCCGCAGTCCCGGAGGACCTGGCATTCGCGGAGAGCCGGATCCGGCCGTC
CACCATCGCGGCCGAGGATCTGCTGCACGATATCGGGGCGATCTCGATGATCGGGAGCGACAGCCAGGCCATGGGGCGCA
TCGGCGAGGTGGTGATGCGAACATGGCAGACCGCGCATGTGATGAAGAAGCGCCGCGGCGCGCTGCCGGGAGATCCATCC
GGGCCCAACGGAAACGACAACAACCGGGTACGCCGGTACGTCGCGAAATACACGATCTGCCCGGCGATCACCCACGGCAT
CGATCACGAGATCGGCTCGGTGGAAGTGGGCAAGCTCGCCGATCTGGTGTTGTGGGAACCGGCGTTTTTCGGGGTGCGGC
CGCATGCGGTCATCAAGGGCGGAGGCATCGTCTGGGCGGCAATGGGCGATGCCAACGCGTCCATTCCCACGCCGCAGCCG
GTGTTCCCGCGCCCGATGTTCAGTGCCATGCATGCCGTCGCGGCGGGGCTGGCGGTGCATTTCGTATCGCCCACGGCCAT
CGAAGATGACCTGGCGGCCCGACTGGCGTTGCGGCGCAGACTGGTCCCAACTCGTGATGTTCGCAACCGTGGCAAGGCGG
ATCTGCCACTCAACGATGCCATGCCCGATATCCGGGTAGACCCCGATACCTTCACCGTGCGTATCGACGGCGAGGTATGG
GAAGAGCATCCCGCTGCGGAATTACCTATGGCGCAACGATATTTCCTGTTCTGA

Protein sequence :
MTRLTREHYAKLYGPTTGDRIRLADTDLIIEITEDRCGGPGLAGEEAVFGGGKVLRESMGQSRLTRAGGAPDTVITGAII
IDHWGIIKADIGIRDGRIVGIGKAGNPDIMDGVDPALIVGPSTEIIAGNNRIVTAGGIDCHVHFICPQILPEALSGGITT
MIGGGTGPAEGSKATTVTPGAWHLGRMLQALDGWPMNILMLGKGNTVNPDAMWEQLRGGAAGFKLHEDWGTTPAVIDACL
RVADEADVQVALHSDTLNETGFVEGTLAAIGGRAIHAYHTEGAGGGHAPDIITVASHPNVMPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNAAVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDSQAMGRIGEVVMRTWQTAHVMKKRRGALPGDPS
GPNGNDNNRVRRYVAKYTICPAITHGIDHEIGSVEVGKLADLVLWEPAFFGVRPHAVIKGGGIVWAAMGDANASIPTPQP
VFPRPMFSAMHAVAAGLAVHFVSPTAIEDDLAARLALRRRLVPTRDVRNRGKADLPLNDAMPDIRVDPDTFTVRIDGEVW
EEHPAAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-147 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-147 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-142 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-141 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-141 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-141 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_2425 YP_001703160.1 Urease, alpha subunit (UreC) VFG0270 Protein 2e-130 56