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Name : MAB_2247c (MAB_2247c) Accession : YP_001702982.1 Strain : Mycobacterium abscessus ATCC 19977 Genome accession: NC_010397 Putative virulence/resistance : Virulence Product : Bifunctional enzyme MbtA : salicyl-AMP ligase + salicyl-S-ArCP synthetase Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : - Position : 2274357 - 2276009 bp Length : 1653 bp Strand : - Note : Similar to P71716_MYCTU 0.0 DNA sequence : ATGACTCAGCCCAGATCGACCACCACCGCGTCGTCAGCCGCAACCCCCGCACTGGATGGTTTCGTCCCGTTTCCCTCGGT ACGCGCCGACGAATATCGCCGGGCCGGGTACTGGACGGGCAACACCGTCGAATCGCTGCTTCGCGTGTCCGCGGCCAGGC GGCCATGCCATCCGGCTGTGATCGACGAACACCGCGCGCTGAGCTATCGAGAACTGGACGAGGCAGCCGACAATGCCGCA CACGCCTTCCTCCGGCTGGGGATAGCGCCCGGCGATCGGGTGCTGCTCCAACTCCCCAATCGGGCATCGTTTGCCGTCGC GCTATTCGGCTTGATGCGTGCCGGCGCAATACCCGTGATGTGCCTTCCCGGGCACCGGGCCGCCGAACTGTCCCACTTCA TCGAGGTGGCCGACGCTGTCGGATTGGTTATCCCCGATTCGGCCGGTGGATTCGATTACCGCGCGCTGGCGGTCGCGCTG TCCCAGCGGCATCCGCGCCTGCGCACGGTGGTCGTGGAGGGTGATGCGGGCCCCTTCGCATCCTGGACGTCGCTGCTGAA AAGTGTTGAGCCGCAGGGTCCGCTACCTACCGTGCAGACGGACACTCCTGCCCTACTGCTGGTGTCCGGCGGCACCACCG CAGCACCCAAGCTGATCCCTCGCACCCACGAGGACTACGTCTACAACGCCACACAGGCAGCACGGGTCTGCGGTCTGACC CAGGACGACGTTTACCTCGTGGCACTGCCCGCCGGCCATAATTTCCCCCTGGCTTGCCCGGGCTTGCTTGGTGCGATAAG CACCGGTGCGACCACGGTTTTCCTCTCGGATCCGAGTCCGGAGTCGGCTTTCGCGACCATCGCTCGCCATCGAGTGTCGG TGACGGCAGTGGTGCCATCGCTTGCACAGCTATGGGCTCAAGCCACCGCGTGGGAGCCGGTGCTGCCGGAAACACTGAGG CTGCTCCAGGTTGGTGGCGCCAAACTCGGCGCCGACGACGCACGAGCGGTACGAGAGTCGCTCACCCAGGGACTGCAACA GGTTTTCGGCATGGCAGAGGGCCTGTTATGCCTCACACAGCCAGGCGATCCCACCGATATCCTGGATAACAGCCAGGGCC GTCCCATGTGCGACGCGGACGAGGTGCGCATAGTCGACGAGGACGGCGCCGACGTCCCCGCCGGAGAAACCGGGGAACTG CTCGTGCGTGGGCCATACACCCTCAACGGGTACTACCGCGCCGACGCCGACAACATGCGCTCGTTCACTGTCGACGGTTT CTATCGCAGCGGTGACCGGGTACGCGCACTACCGGGCGGTTATCTGGAAGTCACCGGACGCATCAAGGATGTCATTCTCC GTGGCGGGGAATCCATCGCCGCGTTGGATCTCGAATCGCACTTGCAGACCCATCCGGCGGTCTACGCCGCAGCGGCGGTG GGCCTTCCCGATCAGTATCTTGGCGAGATTGTCTGTGCTGCAATTGTTTTCAAGGGAAAACCGGTCGCCGCCGCCGAACT CAATCAGCATCTGCAAGCCCGTGGCGCCGCGACCCATTCACGCGTCGACAAACTGGTCGCCGTTTCCGCACTGCCACTGA CCGCTGTGGGCAAGATCGACAAGCGAGCGCTGCTGGCCTCCCTGACGGGCTAG Protein sequence : MTQPRSTTTASSAATPALDGFVPFPSVRADEYRRAGYWTGNTVESLLRVSAARRPCHPAVIDEHRALSYRELDEAADNAA HAFLRLGIAPGDRVLLQLPNRASFAVALFGLMRAGAIPVMCLPGHRAAELSHFIEVADAVGLVIPDSAGGFDYRALAVAL SQRHPRLRTVVVEGDAGPFASWTSLLKSVEPQGPLPTVQTDTPALLLVSGGTTAAPKLIPRTHEDYVYNATQAARVCGLT QDDVYLVALPAGHNFPLACPGLLGAISTGATTVFLSDPSPESAFATIARHRVSVTAVVPSLAQLWAQATAWEPVLPETLR LLQVGGAKLGADDARAVRESLTQGLQQVFGMAEGLLCLTQPGDPTDILDNSQGRPMCDADEVRIVDEDGADVPAGETGEL LVRGPYTLNGYYRADADNMRSFTVDGFYRSGDRVRALPGGYLEVTGRIKDVILRGGESIAALDLESHLQTHPAVYAAAAV GLPDQYLGEIVCAAIVFKGKPVAAAELNQHLQARGAATHSRVDKLVAVSALPLTAVGKIDKRALLASLTG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 7e-98 | 45 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 7e-98 | 45 |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 6e-98 | 45 |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 5e-98 | 45 |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 7e-98 | 45 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 7e-98 | 45 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 7e-98 | 45 |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 9e-97 | 44 |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 1e-96 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| MAB_2247c | YP_001702982.1 | Bifunctional enzyme MbtA : salicyl-AMP ligase + salicyl-S-ArCP synthetase | VFG1817 | Protein | 3e-163 | 63 |
| MAB_2247c | YP_001702982.1 | Bifunctional enzyme MbtA : salicyl-AMP ligase + salicyl-S-ArCP synthetase | VFG0168 | Protein | 3e-90 | 42 |
| MAB_2247c | YP_001702982.1 | Bifunctional enzyme MbtA : salicyl-AMP ligase + salicyl-S-ArCP synthetase | VFG0932 | Protein | 1e-83 | 41 |
