Gene Information

Name : MAB_1197 (MAB_1197)
Accession : YP_001701939.1
Strain : Mycobacterium abscessus ATCC 19977
Genome accession: NC_010397
Putative virulence/resistance : Resistance
Product : Probable cystathionine gamma-synthase (CGS)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1211929 - 1213101 bp
Length : 1173 bp
Strand : +
Note : Similar to Q8L100_RHOER e-171

DNA sequence :
ATGAGTGAGCAGCGCAGCGCCGCCGACGCGTCTCGGTGGCAAGGGTTTTCCACAAGGGCCATCCACGGCGGTTTCCATGC
CGATCCGCAGACCGGTGCGGTCAACGTGCCGATCTACGCCAGTTCGACCTTCGCCCAGGACGGCGTCGGCCAGCTGCGTG
GAGGATTCGAATACGCACGCACCGGCAATCCCACGCGTGCTGTTCTCGAAGCCTCTTTGGCGGCATTGGAAGACGCCCAC
TTCGGCAGGGCGTTCAGTTCCGGGATGGCGGCCACCGACTGCGTGTTGCGCGCGCTGCTGAGGCCGGGCGATCACCTGAT
CATCCCCAATGATGCCTACGGCGGCACCTTCCGGCTGATCGACAAGGTCTTCTCGCAGTGGGGGATCAGACACACTCCGG
TGCCGGTGGCGGACGTCGATGCCATCCGCGCGGCAATTACCCCCACCACCAAGCTGATCTGGCTGGAGACGCCGACCAAC
CCGCTGCTGAGTATCGCCGATATTGCGGCGGTCGCCCAGGTGGCGGCGGAGCATTCCGTGAAGCTGTTGGTGGACAACAC
TTTCGCCTCACCGGCGCTACAGCAGCCGCTGAATCTCGGCGCCGATATCGCGCTGCACTCCACCACCAAATACATTGGCG
GACATTCCGATGTCGTTGGGGGAGCCTTGCTCACCAACGACGAGGAGCTGGACACCGCCTTCGCGTTCCTGCAGAACGGG
GCGGGTGCGGTGCCGGGCCCGTTCGACGGCTACCTGACCTACCGGGGTATCAAGACCTTGGCGTTGCGCATGCAGCGACA
CAGCGAGAACGCGCAAGCGGTGGCCGAGTACCTGGCCGGCCACTCCGCCGTCGCGCAGACGATCTACCCGGGGCTGGAAA
GCCACCCGGGGCATGCCGTGGCCGCCAGGCAGATGCGTGGCTTCGGCGGCATGGTCAGCGTGCGGTTGGCCGGAGGACGC
CAGGCGGCACTCGACTTGTGCTCGCGAACAGAGCTTTTCATTCTGGCTGAGTCCTTGGGCGGGGTGGAGTCCTTGATCGA
GCACCCGGGAGCCATGACGCACGCGTCGACTGCGGGATCGCTGCTGGAGGTGCCGGACGATCTGGTGCGGTTGTCGGTGG
GCATCGAGGAGGTCGGCGATCTGATCGGCGACCTCGAGCAGGCGTTGCGTTAA

Protein sequence :
MSEQRSAADASRWQGFSTRAIHGGFHADPQTGAVNVPIYASSTFAQDGVGQLRGGFEYARTGNPTRAVLEASLAALEDAH
FGRAFSSGMAATDCVLRALLRPGDHLIIPNDAYGGTFRLIDKVFSQWGIRHTPVPVADVDAIRAAITPTTKLIWLETPTN
PLLSIADIAAVAQVAAEHSVKLLVDNTFASPALQQPLNLGADIALHSTTKYIGGHSDVVGGALLTNDEELDTAFAFLQNG
AGAVPGPFDGYLTYRGIKTLALRMQRHSENAQAVAEYLAGHSAVAQTIYPGLESHPGHAVAARQMRGFGGMVSVRLAGGR
QAALDLCSRTELFILAESLGGVESLIEHPGAMTHASTAGSLLEVPDDLVRLSVGIEEVGDLIGDLEQALR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-73 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-74 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-57 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MAB_1197 YP_001701939.1 Probable cystathionine gamma-synthase (CGS) BAC0207 Protein 2e-62 42