Gene Information

Name : Bsph_4649 (Bsph_4649)
Accession : YP_001700223.1
Strain : Lysinibacillus sphaericus C3-41
Genome accession: NC_010382
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4493029 - 4495470 bp
Length : 2442 bp
Strand : -
Note : -

DNA sequence :
ATGTTTAATCGTTTTACACAACGCGCGCAAAAAGTATTACAGCTTGCTCAGGAAGAGGCTATTCGTTGGAAGCACGAATC
CATTGGCACAGAGCACATTTTATTAGGGCTTATACGTGAAGGCGGCGGTATTGCTGCAAAAGCGTTAGAAGCTATTGATA
TTAGTCCTCAAATGATTGAAGCTGGTATTGAAGAATTAGTTGGTAAAGGTAAAGAAGATGTTGGTCCAATCGTTCACTAT
ACGCCACGAGCGAAAAAAGTAATTGAACTATCGGTTGATGAATCTCGTAAATTAGGCCATTCGTATATCGGTACAGAGCA
TTTGCTGTTAGCCCTTATACGTGAAGGTGAAGGTGTAGCAGCTCGCGTCTTAAACAATGCAGGTGTGGGCTTAAATAAAG
CACGTCAGCAAGTATTATTGTTATTAGGGAATAATGATAATGCGCAATCAGGTCAACAAGCGGCACAAGCTGCGAATACC
CCTACATTAGATAGTTTAGCCCGTGATTTAACTCAAATTGCCCGTGAAGGCACGTTAGATCCTGTGATTGGTCGAAGCAA
GGAAATTACACGTGTTATCGAAGTGTTATCGCGTCGTACAAAAAATAACCCTGTTTTAATTGGTGAGCCAGGTGTTGGTA
AAACAGCAATTGCTGAAGGGTTAGCACAGCAAATTATTAATAATGAAGTACCAGAAATTCTTCGAGACAAACGTGTGATG
ACACTAGATATGGGAACTGTCGTTGCAGGCACAAAATATCGTGGGGAATTTGAGGACCGTTTGAAAAAAGTAATGGATGA
AATCCGCCAAGCCGGAAATATCATTTTATTTATTGATGAATTACACACTTTAATCGGTGCAGGTGGTGCAGAAGGTGCAA
TTGACGCATCAAATATTTTAAAACCATCCTTAGCGCGTGGTGAGCTGCAATGTATCGGTGCGACAACGCTTGATGAATAT
CGTAAATATATTGAAAAAGATGCAGCATTAGAGCGTCGTTTCCAACCGATCCAAGTGGATGAACCAACGGTGGAAGAAGC
AATTCTCATTATTCAAGGCTTACGAGATCGCTATGAAGCACATCACCGAGTGAAAATTACAGATGAAGCAATTGAAGCAG
CGGCAAAAATGGGTGATCGATATATTTCTGACCGCTTCTTACCAGATAAAGCAATTGACCTGATTGATGAAGCAGGATCA
AAGGTTCGCTTACGTTCATTCGCAGTGCCACCAAACTTAAAGGCACTTGAAGATAAGCTTGAAAATGTTCGCTCTGAAAA
GAATGCTGCTGTATCAGGTCAAGAGTTTGAAAAGGCTGCTGCGTTAAGAGATACGGAGCAAAAGCTTAAAGATGAGATTG
AAGCTACAAGAAAAAATTGGAAAGAAGAGCAAGGTAAAGCCGAGTCCAAAGTAACAGTAGATGATGTTGCAGCAGTTGTA
TCAATGTGGACAGGAATTCCTGTAGCTAAAATTGCTTCTGAAGAATCTTCAAAATTATTACAACTTGAAGAAGAGCTACA
CAAACGTGTGGTTGGGCAAGGGGAAGCAGTAGAAGCCATTTCCCGTGCGATCCGTCGTGCAAGAGCGGGCCTCAAAGATC
CAAAACGACCAATCGGTTCATTTATTTTCTTAGGTCCTACTGGTGTTGGTAAAACGGAGCTTGCAAGAGCACTTGCTGAA
GTGATGTTTGGTGACGAAGATGCTATGATTCGTGTCGATATGTCTGAGTACATGGAGAAACATTCAACTTCTCGTTTAGT
AGGTTCACCTCCAGGCTACGTAGGCTTTGATGATGGTGGTCAATTGACTGAAAAGGTTCGTCGTAAACCATATTCTGTTG
TATTACTAGATGAAATTGAAAAAGCACACCCTGATGTTTTCAATATTCTCCTGCAAGTTCTTGAAGATGGTCGATTAACG
GACTCTAAGGGGCGTGTAGTAGACTTCCGCAACACAGTAGTGATAATGACTTCTAACGTCGGCGCGGATGCTCTTAAATA
TCAAAAAAGCCTTGGTTTTAACGTAGGTGGTGCAGATTCTAAACATAAAGATATGAAGAGTACGATGCTCGAAGAATTGA
AAAAAGCATTCCGTCCAGAATTCTTAAACCGTATTGATGAAATGATTGTGTTCCATTCATTAGAAAAAGAGCATTTAAAA
GAAATCATTGCGATGATGGGGAACGCTCTAACAAAGCGGTTGAAAGAACAGGATATTTCATTAGAATTAACAGATGCAGC
GCTTGAAAAAATTGCTCAGGAGGGCTACGACCCTCAATACGGTGCACGTCCACTACGTCGAGCATTACAAAAACAAGTGG
AAGACCGATTATCAGAAGAATTATTAAAGGGTAATGTGGAGAAGGGTAATCATGTTATCATTGATTATGTAAATGACGAG
TTTATTGTGAAGAAAAAAGAGGGAGTTTCTATCTCTAAATAA

Protein sequence :
MFNRFTQRAQKVLQLAQEEAIRWKHESIGTEHILLGLIREGGGIAAKALEAIDISPQMIEAGIEELVGKGKEDVGPIVHY
TPRAKKVIELSVDESRKLGHSYIGTEHLLLALIREGEGVAARVLNNAGVGLNKARQQVLLLLGNNDNAQSGQQAAQAANT
PTLDSLARDLTQIAREGTLDPVIGRSKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDEPTVEEAILIIQGLRDRYEAHHRVKITDEAIEAAAKMGDRYISDRFLPDKAIDLIDEAGS
KVRLRSFAVPPNLKALEDKLENVRSEKNAAVSGQEFEKAAALRDTEQKLKDEIEATRKNWKEEQGKAESKVTVDDVAAVV
SMWTGIPVAKIASEESSKLLQLEEELHKRVVGQGEAVEAISRAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
VMFGDEDAMIRVDMSEYMEKHSTSRLVGSPPGYVGFDDGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRVVDFRNTVVIMTSNVGADALKYQKSLGFNVGGADSKHKDMKSTMLEELKKAFRPEFLNRIDEMIVFHSLEKEHLK
EIIAMMGNALTKRLKEQDISLELTDAALEKIAQEGYDPQYGARPLRRALQKQVEDRLSEELLKGNVEKGNHVIIDYVNDE
FIVKKKEGVSISK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bsph_4649 YP_001700223.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 74
Bsph_4649 YP_001700223.1 negative regulator of genetic competence clpC/mecB VFG0080 Protein 2e-143 52