Gene Information

Name : msrA (Bsph_4526)
Accession : YP_001700102.1
Strain : Lysinibacillus sphaericus C3-41
Genome accession: NC_010382
Putative virulence/resistance : Resistance
Product : erythromycin resistance ATP-binding protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG0488
EC number : -
Position : 4381837 - 4383285 bp
Length : 1449 bp
Strand : -
Note : -

DNA sequence :
ATGGAAAAAGTTTGCTTTGAATTAGATCGCCTAATTGTAAGTTATTTAGATAAAGAGATTTTAAACATTGAAAAATTGGC
CATTCACCAATTTGATCGTATCGGTATCGTTGGGAAAAATGGCGCTGGGAAAAGTACATTAATGAAGATACTGGCTAGCA
AGATTCAGCCCACAAGTGGGATAGTAAAAAGTCATGTACATTTCGGTTATTTTGAACAAATGGAAGCACCAATGCTCGTA
GAGGCGGAGGGACAGTTATTAGGGAAATTAGCTATTCCATCAAATTCTGAGGGACTAAGTGGTGGAGAGCAAACGAGATT
AAAGTTAGCTCAATTATTCTCCTATTATAAGGAGGCACTGCTCATTGATGAGCCAACGACACATTTAGATCAAGAGGGTA
TTTCATTTCTAGTGGATGAATTGCGTTATTACTATGGTGCGCTCGTACTAATTAGCCATGATCGAGCGGTTCTGGATGAA
TTGGTCACAACAATTTGGGAGATTGATGGGGGCACAGTAAACATTTATTCGGGCAATTATAGTAATTATGCTTGGCAAAA
GCAGCTGGAGCGAGATCAACAACGTCAGGCGCATGACTTGTACTTGAAAGAAAGAAGTCGTCTTGAAAAATCTGCTGAAG
ATAAAATGAAAAAGGCTGAAAAAATTACCCAAGCAGGTAACATGTCAAAAAGAGAAGCTCATGCAAAACCGAACCTTACG
TTTATGACAAAGTCCAAAGGTACAAGTCAAAAAAACGTACAACGGGCAGCCAAGGCAATAGAACAGCGAATAGAGAAGCT
TCAGAAAGTAGATGCGGTGCAGGTAGACAGAAAAATAGTTTTTCGACAATCGAAAGCTTTAGAACTGCACAATAAATTTC
CGATTATGGCAGATCAATTCACGTTACACGTTCCGGGAAAAGCACTATTGGAAGAAGTAAACTTCCAAATACCATTGGGT
AAAAAAATTGTGCTTACAGGTAGTAATGGTTGCGGAAAGAGTACATTATTACGATATATTGCAACTAATGGGGAGGGATT
GACCATTTCTCCTAAGGCTAAAGTCGGCTATTTTAATCAAATGAGCTATCAATTTAAAAGTGAGGAAACAGTTCTCCAAT
TTTTAAAAAATCGCGCTGATTACGATGAAGGCTTTTTAAGAAATATTTTAAGTTCCATGCAATTTGTAGGAACTGATATA
CAAAAGAGTGTGAACTCATTAAGCGGTGGGGAAGCAATACGCCTCCAGCTATGTTATCTGTTTTTGGGAAACTATAATAT
ACTGTTATTGGATGAGCCAACCAACTTCTTAGATATTCAAGCATTAGAAGCGCTAGAGCAATTTATAACGGCTTATGAGG
GGACCGTAATCTTCGTGACCCATGATAAAAATTTTATCGAAAATGTAGCAGACATACACCTCACAATAAAAAATAATAAG
ATATTTTAA

Protein sequence :
MEKVCFELDRLIVSYLDKEILNIEKLAIHQFDRIGIVGKNGAGKSTLMKILASKIQPTSGIVKSHVHFGYFEQMEAPMLV
EAEGQLLGKLAIPSNSEGLSGGEQTRLKLAQLFSYYKEALLIDEPTTHLDQEGISFLVDELRYYYGALVLISHDRAVLDE
LVTTIWEIDGGTVNIYSGNYSNYAWQKQLERDQQRQAHDLYLKERSRLEKSAEDKMKKAEKITQAGNMSKREAHAKPNLT
FMTKSKGTSQKNVQRAAKAIEQRIEKLQKVDAVQVDRKIVFRQSKALELHNKFPIMADQFTLHVPGKALLEEVNFQIPLG
KKIVLTGSNGCGKSTLLRYIATNGEGLTISPKAKVGYFNQMSYQFKSEETVLQFLKNRADYDEGFLRNILSSMQFVGTDI
QKSVNSLSGGEAIRLQLCYLFLGNYNILLLDEPTNFLDIQALEALEQFITAYEGTVIFVTHDKNFIENVADIHLTIKNNK
IF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
msr(E) YP_005176244.1 macrolide efflux protein Not tested ICEPmu1 Protein 9e-100 43
msrSA YP_254220.1 erythromycin resistance protein Not tested ¥ðSh1 Protein 2e-84 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
msrA YP_001700102.1 erythromycin resistance ATP-binding protein NC_012469.1.7685970. Protein 7e-102 46