Gene Information

Name : SPH_0941 (SPH_0941)
Accession : YP_001694297.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Unknown
Product : pyrimidine-nucleoside phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.2
Position : 866750 - 868027 bp
Length : 1278 bp
Strand : +
Note : Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway

DNA sequence :
ATGAGAGCAGTTGATTTAATCCAAAAAAAACGAGACGGTCAAGAACTGACTTCAAGTGAAATTGAATGGCTGATAGAAGG
CTATGTATCAGGAACTGTTCCTGATTATCAGATGTCTGCCTTTGCTATGGCTGTTTATTTTAAAGGAATGACGACTCGAG
AAATCTCTGATTTAACGATGAATATGGTTAAGACTGGGCAAGAGTTTGACCTGTCAGCCATTGATGGTGTGAAAGTTGAC
AAGCATTCTACTGGTGGTGTCGGCGATAAGGTAACCTTGATTTTAGCTCCTCTTGTTGCTAGCTTCGGTGTGCCTGTAGC
AAAAATGAGTGGTCGTGGTCTTGGCCATACAGGCGGAACAATTGATAAATTGGAGTCCATTAAGGGCTATCAAGTAGAAC
GTAGTCAAGAGGATTTTATTCGTCAGGTTCAGGATATTGGAGTATCTGTCATTGGGCAATCAGACCAGCTGGTCAAAGCA
GATAAGCTTCTCTATGCCCTTCGTGATGTGACCGCAACTGTCGACACGATTCCTTTGATTGCGAGTTCGGTGATGAGCAA
GAAAATTGCGGCAGGGGCGGATGCTATTTTGCTAGACGTGACTGTCGGTGAGGGTGCCTTCATGAAGACGGTTGATGAGG
CGCGTGAGTTGGCTCAAACTATGGTAGATCTTGGTAAGGTTGTTGGACGGAAGACAGTAGCAGTGATTACGGATATGAGC
CAGCCTTTGGGACGAGCGATTGGAAATCGTCTGGAAATCCTTGAAGCATTGGAGATTTTGCAAGGTCAAGGACGTCAGGA
TATTACCCACTTTATTTGTGAATTGGCTCAAATTATGCTTGGTTTGGCAAATGTTAACAAAACTGTTGAAGAAGTTCGCC
AACATCTTGAAAATGGTCAAGCACTGGCTAAGTTTGAGGAAATGGTGCAAGCCCAAGGTGGAGACTTGGAAGACCTCTAT
CGTCCTGTAAATGTAGCTCATGTGGTGGAAATCCCTGCTCAGGAAACGGGTGTCATTTCAGCTCTTCCAGCTATGGACTT
TGGTCTTTATGCCATGAGGCTGGGTGCTGGTCGTGCAGTTAAGTCTGATGTCTTGGACTATGAAACAGGAATTGTTTTTG
AAAAGAAGATTGGAGACTCCGTTCAAAAGGGTGAAATTGTTGCAAAAGTATACACAAATGGAAAAATTTCTCCTCAGCTA
GTTACAGATTTTCAAAAATATGTTAAAATAAATGATAGGGTGCAAAGTTTACGAGAAATTATAGAAACCATCTCATAA

Protein sequence :
MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMAVYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVD
KHSTGGVGDKVTLILAPLVASFGVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELAQTMVDLGKVVGRKTVAVITDMS
QPLGRAIGNRLEILEALEILQGQGRQDITHFICELAQIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLY
RPVNVAHVVEIPAQETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYTNGKISPQL
VTDFQKYVKINDRVQSLREIIETIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 2e-87 49